Abstract: Provided is a liquid crystal display device comprising a first substrate, a second substrate, and a liquid crystal composition disposed between said first substrate and said second substrate, wherein a surface of said first substrate in contact with said liquid crystal composition is provided with an alignment layer, while said second substrate has no alignment layer; and said liquid crystal composition comprises a liquid crystal compound, a self-aligning agent, and a polymerizable compound represented by Formula I,

Abstract: A dielectric negative liquid crystal composition, a liquid crystal display element and a liquid crystal display containing the liquid crystal composition belong to the field of liquid crystal display. The liquid crystal composition of the present disclosure includes a compound represented by formula I, a compound represented by formula II, two or more compounds represented by formula III and one or more compounds represented by formula IV. The liquid crystal composition of the present invention has high dielectric anisotropy, high elastic constant K, low rotational viscosity, can be used to develop large dielectric, fast response liquid crystal display elements or liquid crystal displays.

Abstract: A liquid crystal composition, a liquid crystal display element and a liquid crystal display comprising the liquid crystal composition belong to the field of liquid crystal display. The liquid crystal composition comprises a compound represented by formula I with a mass content of 1-10% as the first component, a compound represented by formula II with a mass content of 1-20% as the second component, more than two compounds represented by formula III as the third component, more than three compounds represented by formula IV as the fourth component, and one or more polymerizable compounds as the fifth component, the crystal composition has low rotational viscosity and low ?1/K33 on the basis of maintaining appropriate optical anisotropy. When applied to liquid crystal display elements or liquid crystal displays, the liquid crystal display has a fast response speed.

Abstract: The present invention relates to a liquid crystal display device. The liquid crystal display device of the present invention comprises a first substrate, a second substrate, and a liquid crystal composition disposed between said first substrate and said second substrate, wherein said first substrate and said second substrate are disposed in parallel and opposite to each other, with the distance between said first substrate and said second substrate being 2.5 ?m to 3.2 ?m; alignment layers are disposed on the sides of said first and second substrates that are close to said liquid crystal composition; and said alignment layers are provided with vertical alignment films that allow liquid crystal molecules in said liquid crystal composition to be arranged roughly perpendicular to said first or second substrate.

Abstract: Disclosed is a liquid crystal composition comprising one or more compounds represented by formula I, one or more compounds represented by formula II, and one or more compounds represented by formula III: The liquid crystal composition has simultaneously a lower rotary viscosity, a better photoelectric performance, a higher clearing point, a good low temperature performance, and less display defects. Further disclosed is a liquid crystal display element or device comprising the liquid crystal composition.

Abstract: Provided is a selective transfer method including depositing a thin film on a substrate; patterning the thin film using a laser or a tool to acquire a thin film of a target pattern; masking the thin film of the target pattern; selectively controlling a surface wettability through surface treatment of the masked thin film; delaminating the thin film of the target pattern by dipping a surface of the thin film with a wettability changed in response to a completion of the selective surface treatment into a liquid material and by applying a crack opening force capable of delaminating an interface between the thin film and the substrate; and immersing a target substrate into the liquid material when the thin film of the target pattern is floating in the liquid material and then scoop-up transferring the floating thin film of the target pattern.

Abstract: Provided is a liquid crystal compound containing 2,3,4-trisubstituted benzene, a liquid crystal composition thereof, and a liquid crystal display element or a liquid crystal display comprising the liquid crystal compound or the liquid crystal composition, wherein the liquid crystal composition has a lower viscosity, can achieve a quick response, and further has a moderate dielectric anisotropy ??, a moderate optical anisotropy ?n, and high stability to heat and light. The liquid crystal display element or liquid crystal display comprising the liquid crystal composition has the properties of a wider nematic phase temperature range, an appropriate birefringence anisotropy, a very high electrical resistivity, a good ultraviolet resistant property, a high charge retention rate, a low vapor pressure etc., and particularly, the liquid crystal compound or the liquid crystal composition has the advantage of a high light transmittance.

Abstract: The present disclosure relates to a liquid crystal composition, and a liquid crystal display element or liquid crystal display comprising the liquid crystal composition, and belongs to the field of liquid crystal display, wherein the liquid crystal composition of the present disclosure comprises a compound represented by formula I, one or more compounds represented by formula II, one or more compounds represented by formula III, one or more compounds represented by formula IV, and at least one polymerizable compound, and has a large dielectric anisotropy (??) and a large optical anisotropy (?n), and has an obvious advantage in the development of a liquid crystal display having a high transmittance and a low cell thickness.

Abstract: The present disclosure relates to a liquid crystal composition, and a liquid crystal display element or liquid crystal display comprising the liquid crystal composition, and belongs to the field of liquid crystal display, the liquid crystal composition of the present disclosure comprising a compound represented by formula I, one or more compounds represented by formula II, one or more compounds represented by formula III, and at least one polymerizable compound, wherein the liquid crystal composition simultaneously has a low rotary viscosity (?1), a larger dielectric anisotropy (??), and a fast response speed.

Abstract: The present disclosure relates to a liquid crystal composition, and a liquid crystal display element or liquid crystal display comprising the liquid crystal composition, and belongs to the field of liquid crystal display, said liquid crystal composition comprises a compound represented by formula I, a compound represented by formula II, one or more compounds represented by formula III, and at least one polymerizable compound, wherein the liquid crystal composition simultaneously has a low rotary viscosity, a large refractive index, and a fast response speed.

Abstract: The present disclosure relates to a liquid crystal composition, and a liquid crystal display element or liquid crystal display comprising the liquid crystal composition, and belongs to the field of liquid crystal display. The liquid crystal composition of the present disclosure comprises a compound represented by formula I, a compound represented by formula II, one or more compounds represented by formula III, and at least one polymerizable compound, the liquid crystal composition having a higher clearing point (CP), a large K value, a suitable optical anisotropy (?n), and a fast response speed.

Abstract: The present invention provides a liquid crystal composition comprising one or more compounds of general formula I and one or more compounds of general formula II; the liquid crystal composition of the present invention can work at very high and very low temperatures, has a very short response time and a better reliability to light and heat, and particularly exhibits no image retention or a significantly reduced image retention after a long time operation.

Abstract: The present invention relates to a liquid crystal display device. The liquid crystal display device of the present invention comprises a first substrate, a second substrate, and a liquid crystal composition disposed between said first substrate and said second substrate, wherein said first substrate and said second substrate are disposed in parallel and opposite to each other; alignment layers are disposed on the sides of said first and second substrates that are close to said liquid crystal composition; and said alignment layers are provided with vertical alignment films that allow liquid crystal molecules in said liquid crystal composition to be arranged roughly perpendicular to said first and second substrates, with said liquid crystal molecules having a pretilt angle of 88.5° to 89.5°.

Abstract: The present invention relates to a liquid crystal display device. The liquid crystal display device of the present invention comprises a first substrate, a second substrate, and a liquid crystal composition disposed between said first substrate and said second substrate, wherein said first substrate and said second substrate are disposed in parallel and opposite to each other, with the distance between said first substrate and said second substrate being 2.5 ?m to 3.2 ?m; alignment layers are disposed on the sides of said first and second substrates that are close to said liquid crystal composition; and said alignment layers are provided with vertical alignment films that allow liquid crystal molecules in said liquid crystal composition to be arranged roughly perpendicular to said first or second substrate.

Abstract: A method for coating a thin film in a rolling manner and a thin film coating apparatus are provided. The method includes: floating a thin film material on a liquefied material; rolling a cylindrical substrate after contacting the cylindrical substrate with the thin film material; and coating the thin film material on a surface of the cylindrical substrate by using an attraction force between the surface of the cylindrical substrate and the thin film material.

Abstract: Provided is a liquid crystal display device comprising a first substrate, a second substrate, and a liquid crystal composition disposed between said first substrate and said second substrate, wherein a surface of said first substrate in contact with said liquid crystal composition is provided with an alignment layer, while said second substrate has no alignment layer; and said liquid crystal composition comprises a liquid crystal compound, a self-aligning agent, and a polymerizable compound represented by Formula I,

Abstract: In certain embodiments, the disclosure relates to methods of treating or preventing a PGAM1 mediated condition such as cancer or tumor growth comprising administering an effective amount of PGAM1 inhibitor, for example, an anthracene-9,10-dione derivative to a subject in need thereof. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer, head and neck cancer, and leukemia, comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a compound disclosed herein or pharmaceutically acceptable salt to a subject in need thereof.

Abstract: Provided is a liquid crystal compound containing 2,3,4-trisubstituted benzene, a liquid crystal composition thereof, and a liquid crystal display element or a liquid crystal display comprising the liquid crystal compound or the liquid crystal composition, wherein the liquid crystal composition has a lower viscosity, can achieve a quick response, and further has a moderate dielectric anisotropy ??, a moderate optical anisotropy ?n, and high stability to heat and light. The liquid crystal display element or liquid crystal display comprising the liquid crystal composition has the properties of a wider nematic phase temperature range, an appropriate birefringence anisotropy, a very high electrical resistivity, a good ultraviolet resistant property, a high charge retention rate, a low vapor pressure etc., and particularly, the liquid crystal compound or the liquid crystal composition has the advantage of a high light transmittance.

Abstract: In certain embodiments, the disclosure relates to methods of treating or preventing a PGAM1 mediated condition such as cancer or tumor growth comprising administering an effective amount of PGAM1 inhibitor, for example, an anthracene-9,10-dione derivative to a subject in need thereof. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer, head and neck cancer, and leukemia, comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a compound disclosed herein or pharmaceutically acceptable salt to a subject in need thereof.

Abstract: Disclosed is a liquid crystal composition comprising one or more compounds represented by formula I, one or more compounds represented by formula II, and one or more compounds represented by formula III: The liquid crystal composition has simultaneously a lower rotary viscosity, a better photoelectric performance, a higher clearing point, a good low temperature performance, and less display defects. Further disclosed is a liquid crystal display element or device comprising the liquid crystal composition.