Patents by Inventor Sumio Maeda

Sumio Maeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human and animal cell culture medium containing antithrombin III for suppressing cell death
    Patent number: 6858428
    Abstract: The present invention provides low serum or serum free liquid culture media for human or animal cells, and the present invention relates to culture media containing antithrombin III and optionally heparin for the low-serum or serum-free culture of human or animal cells to suppress cell death. The antithrombin III is purified from human, bovine, or other animal serum, or antithrombin III derived from recombinant bacteria or cells containing the full length of the antithrombin III gene.
    Type: Grant
    Filed: August 8, 2002
    Date of Patent: February 22, 2005
    Assignee: Agency of Industrial Science and Technology
    Inventors: Takao Saito, Sumio Maeda, Hidetoshi Inagaki
  • Monolayer sheet structure of primary hepatocytes obtained using a protein-phosphorylation inhibitor
    Patent number: 6632668
    Abstract: A monolayer sheet structure is prepared containing a confluent monolayer of primary hepatocytes cultured on a substrate in sheet form. The monolayer sheet structure is formed by treating the hepatocytes in the monolayer formation stage with a protein-phosphorylation inhibitor having an indolo [2,3-a] carbazole structure, such as staurosporine, or other similar structure.
    Type: Grant
    Filed: December 27, 2000
    Date of Patent: October 14, 2003
    Assignee: Japan as represented by the Secretary of Agency of Industrial Science and Technology
    Inventors: Sumio Maeda, Hidetoshi Inagaki, Takao Saito
  • Human and animal cell culture medium
    Publication number: 20020197719
    Abstract: The present invention provides liquid culture media for human or animal cells, and the present invention relates to culture media for the low-serum or serum-free culture of human or animal cells, which contains antithrombin III purified from human, bovine, or other animal serum, or antithrombin III derived from recombinant bacteria or cells containing the full length of the antithrombin III gene.
    Type: Application
    Filed: August 8, 2002
    Publication date: December 26, 2002
    Applicant: Japan as represented by Secretary of Agency of Industrial Science and Technology
    Inventors: Takao Saito, Sumio Maeda, Hidetoshi Inagaki
  • Continuous cell-sheet structure consisting of monolayer of primary hepatocytes and the method of forming the sheet
    Publication number: 20010055806
    Abstract: The present invention provides a monolayer sheet structure of primary hepatocytes that could not be formed by conventional cell layer formation technology, along with a simple method of forming such a monolayer sheet structure, and this invention is a monolayer sheet structure formed as a confluent monolayer of primary hepatocytes cultured on a culture substrate, said monolayer sheet structure is formed by treating the hepatocytes with a protein-phosphorylation inhibitor having an indolo [2,3-a] carbazole or other similar structure in the monolayer formation stage.
    Type: Application
    Filed: December 27, 2000
    Publication date: December 27, 2001
    Applicant: Japan as represented by Secretary of Agency of Industrial Science and Technology
    Inventors: Sumio Maeda, Hidetoshi Inagaki, Takao Saito