Patents by Inventor Summer L Gibbs

Summer L Gibbs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications
    Publication number: 20230287217
    Abstract: The present invention provides novel Zwitterionic cell-permeant and water-soluble rhodamine dye compounds, pharmaceutical composition comprising them, and methods for their use in quantitative imaging applications, particularly substituted 5,5-dimethyl-10-phenyl-3,5-dihydrodibenzo[b,e]siline and 9- phenyl-3H-xanthene compounds of Formula (I).
    Type: Application
    Filed: October 6, 2021
    Publication date: September 14, 2023
    Inventors: Summer L. Gibbs, Lei G. Wang, Antonio R. Mantaño
  • OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING
    Publication number: 20230148317
    Abstract: This invention concerns novel oxazine-based fluorophore compounds useful in in vivo nerve imaging, as well as compositions comprising them and methods for their use.
    Type: Application
    Filed: January 22, 2021
    Publication date: May 11, 2023
    Applicant: Oregon Health & Science University
    Inventors: Summer L. Gibbs, Lei G. Wang, Connor W. Barth
  • NERVE SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION
    Publication number: 20230098686
    Abstract: Nerve-specific fluorophore formulations of Formula (I) for direct or systemic administration are described. The formulations can be used in fluorescence-guided surgery (FGS) to aid in nerve preservation during surgical interventions.
    Type: Application
    Filed: April 9, 2021
    Publication date: March 30, 2023
    Inventors: Summer L Gibbs, Lei Wang, Connor W. Barth
  • OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING
    Publication number: 20230098438
    Abstract: This invention provides novel oxazine-based, water soluble fluorophore compounds useful in in vivo nerve imaging, as well as compositions comprising them and methods for their use.
    Type: Application
    Filed: December 21, 2020
    Publication date: March 30, 2023
    Applicant: Oregon Health & Science University
    Inventors: Summer L. Gibbs, Lei G. Wang, Connor W. Barth
  • Near-infrared nerve-sparing fluorophores
    Patent number: 11492359
    Abstract: The compounds provided herein are phenoxazines that can be used as far red to near-infrared nerve-sparing fluorescent compounds in medical procedures.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: November 8, 2022
    Assignee: Oregon Health & Science University
    Inventors: Summer L. Gibbs, Lei G. Wang, Connor W. Barth
  • NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES
    Publication number: 20220041619
    Abstract: Provided are near-infrared nerve-sparing fluorescent compounds, compositions comprising them, and methods of their use in medical procedures.
    Type: Application
    Filed: September 11, 2019
    Publication date: February 10, 2022
    Applicant: OREGON HEALTH & SCIENCE UNIVERSITY
    Inventors: Summer L. Gibbs, Lei G. Wang, Connor W. Barth
  • NEAR-INFRARED NERVE-SPARING FLUOROPHORES
    Publication number: 20210317137
    Abstract: Provided are far red to near-infrared nerve-sparing fluorescent compounds, compositions comprising them, and methods of their use in medical procedures.
    Type: Application
    Filed: July 26, 2019
    Publication date: October 14, 2021
    Applicant: OREGON HEALTH & SCIENCE UNIVERSITY
    Inventors: Summer L. Gibbs, Lei G. Wang, Connor W. Barth
  • NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION
    Publication number: 20210236657
    Abstract: Nerve-specific fluorophore formulations for direct or systemic administration are described. The formulations can be used in fluorescence-guided surgery (FGS) to aid in nerve preservation during surgical interventions.
    Type: Application
    Filed: August 6, 2019
    Publication date: August 5, 2021
    Applicants: OREGON HEALTH & SCIENCE UNIVERSITY, OREGON STATE UNIVERSITY
    Inventors: Summer L. Gibbs, Connor W. Barth, Wathah G. Alani, Vidhiben Shah, Lei Wang
  • NILE RED DERIVATIVES FOR IMPROVED RATIOMETRIC IMAGING FOR NERVE SPECIFIC CONTRAST
    Publication number: 20210115000
    Abstract: Provided herein are novel Nile Red derivatives with varied electron donating and withdrawing groups to try to influence tissue-specific accumulation and generate a truly adipose specific fluorophore of Formula (I).
    Type: Application
    Filed: April 26, 2019
    Publication date: April 22, 2021
    Inventors: Jesse R Korber, Connor W Barth, Summer L Gibbs