Abstract: Disclosed is a hemostasis valve device including a connector including a first channel, a holder disposed at a first end of the connector and configured to communicate with the first channel, and a valve portion disposed at a second end of the connector and configured to selectively open or close the first channel. Here, the connector includes a first pipe including the first channel and a second pipe which diverges from a first point of the first pipe and includes a second channel configured to communicate with the first channel. Also, the first pipe includes a hole which allows the first channel to communicate with the outside. Here, the hemostasis valve device further includes an opening and closing portion disposed at the first pipe and configured to selectively open or close the hole. The hole is disposed between the first end and the first point.

Abstract: The present invention may provide a medical syringe comprising: a cylinder including a stopper protruding inward; and a plunger disposed inside the cylinder so as to move back and forth in a first direction, wherein the plunger includes a plurality of protrusions, and the plurality of protrusions are arranged at intervals along the longitudinal direction of the plunger, and based on the first direction, any one of the stopper or the plurality of protrusions is arranged so as to be selectively overlapped according to the rotation of the plunger.

Abstract: Disclosed is a hemostasis valve device including a connector including a first channel, a holder disposed at a first end of the connector and configured to communicate with the first channel, and a valve portion disposed at a second end of the connector and configured to selectively open or close the first channel. Here, the connector includes a first pipe including the first channel and a second pipe which diverges from a first point of the first pipe and includes a second channel configured to communicate with the first channel. Also, the first pipe includes a hole which allows the first channel to communicate with the outside. Here, the hemostasis valve device further includes an opening and closing portion disposed at the first pipe and configured to selectively open or close the hole. The hole is disposed between the first end and the first point.

Abstract: The present invention relates to a hemostasis valve device which allows a wire or a catheter to be inserted into the left or right coronary artery via the femoral artery or an arm artery when a Cardiac Catheterization or Percutaneous Transluminal Coronary Angioplasty operation is performed, wherein two independent sealing members are opened and closed by press and release actions of push buttons coupled to a body and the rotation of a fastening tube, respectively, so that the leakage of blood or the inflow of outside air is simply and effectively blocked during the operation, and a drug influx tube for allowing a medicine such as a thrombolitic drug to flow into a patient during the operation pivots and is adjusted in a stepwise manner within a certain range of angles according to body conditions or movements of the patient.

Abstract: An instillator for injection of a Ringer's solution temporarily stores Ringer's solutions or others, and couples a precise flow regulator onto an instillation container, thereby allowing the solutions to be administered more accurately, preventing accidents from happening because the regulator is out of a patient's reach, and allowing a connected tube to be easily arranged. The instillator includes an instillation container, a solution inflow tube with a penetration needle and a solution guide passage, and a lower stopper with a solution drainage passage and a tube connector, wherein a drainage guide plate with a drainage hole is inserted into the container to discharge a solution downwardly, a precise flow regulator is coupled onto the plate to be rotated from side to side, and an instillation hole communicating with the tube connector is formed in the regulator.

Abstract: The present invention relates to a hemostasis valve device which allows a wire or a catheter to be inserted into the left or right coronary artery via the femoral artery or an arm artery when a Cardiac Catheterization or Percutaneous Transluminal Coronary Angioplasty operation is performed, wherein two independent sealing members are opened and closed by press and release actions of push buttons coupled to a body and the rotation of a fastening tube, respectively, so that the leakage or blood or the inflow of outside air is simply and effectively blocked during the operation, and a drug influx tube for allowing a medicine such as a thrombolytic drug to flow into a patient during the operation pivots and is adjusted in a stepwise manner within a certain range of angles according to body conditions or movements of the patient.

Abstract: The present invention relates to process for the preparing of optically active ester derivatives and their acid derivatives which are used intensively as important chiral intermediates from racemic ?-hydroxybutyl ester derivatives. In more detail, this invention relates to the process for preparing optically active ?-hydroxybutyl ester derivatives and their acid derivatives by stereospecific hydrolysis of racemic ?-hydroxybutyl ester derivatives using Upases or lipase-producing microorganisms in the aqueous phase or organic phase including aqueous solvent. The method of making optically active ester derivatives and their acid derivatives by hydrolysis of ?-hydroxybutyl ester derivatives represented by the general formula 1 in scheme 1 is easier and more economical comparing to the conventional methods and the products have high optical purity. Also separation of ester derivatives from acid derivatives is easy after reaction. Thus this method is a useful process on the industrial scale.