Abstract: A drug delivery composition includes a polymer, and one or more drugs and a bioactive polyelectrolyte complex dispersed within the polymer where the polyelectrolyte complex regulate the release of the drugs from the polymer. The bioactive polyelectrolyte complex comprises a polyelectrolyte and an oppositely charged component, wherein the polyelectrolyte and/or the oppositely charged component is bioactive.

Abstract: Universal, biocompatible coating platforms for articles intended to contact physiological fluids or tissues and associated methods of production are disclosed. The coating platforms of the present invention are composed of a polyelectrolyte molecular film containing one or more biologically active compounds. The molecular film is further complexed with the surface of an article by a crosslinked interpenetrating network (IPN) made from at least one multifunctional molecule and at least one crosslinking agent. The IPN may entrap additional biologically active compounds within the coating platform, or additional biologically active compounds may be bound to its outer surface. The coating platform of the present invention is ideally suited for providing medical devices with anti-thrombogenic coatings.

Abstract: A filter material comprising hydrophobic filter media treated with a wetting agent which consists essentially of a material selected from the group consisting of polysobate 20, polysorbate 40, polysorbate 60 and polysorbate 80. The wetting agent is applied by dissolving it in a solvent and spraying the resulting solution onto the filter media.