Patents by Inventor Sun Hee Leem

Sun Hee Leem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9884086
    Abstract: Disclosed is a method for providing information used for comparing restoration rates of damaged DNA, wherein information about a time period when Ataxia telangiectasia and Rad3 related (‘ATR’) activation is accelerated, on the basis of alternative information about an expression level of cryptochrome may be acquired, therefore, it can be determined that a restoration rate of damaged DNA is high at a time period when the expression level of cryptochrome is high. Accordingly, a time period when a restoration rate of DNA damaged by different causes is high, can be determined. Further, it is possible to estimate a time period when side effects occurring due to using an anticancer drug are minimized, and then, utilize the estimated result in determining the timing of administration of an anticancer drug.
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: February 6, 2018
    Assignee: DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY—ACADEMY COOPERATION
    Inventors: Tae Hong Kang, Jeong Min Park, Ji Ye Choi, Sun Hee Leem
  • Publication number: 20150290282
    Abstract: Disclosed is a method for providing information used for comparing restoration rates of damaged DNA, wherein information about a time period when Ataxia telangiectasia and Rad3 related (‘ATR’) activation is accelerated, on the basis of alternative information about an expression level of cryptochrome may be acquired, therefore, it can be determined that a restoration rate of damaged DNA is high at a time period when the expression level of cryptochrome is high. Accordingly, a time period when a restoration rate of DNA damaged by different causes is high, can be determined. Further, it is possible to estimate a time period when side effects occurring due to using an anticancer drug are minimized, and then, utilize the estimated result in determining the timing of administration of an anticancer drug.
    Type: Application
    Filed: November 24, 2014
    Publication date: October 15, 2015
    Inventors: Tae Hong KANG, Tae Hee LEE, Jeong Min PARK, Ji Ye CHOI, Sun Hee LEEM
  • Publication number: 20150275313
    Abstract: The present disclosure relates to a novel function of a specific gene and has an effect of providing a composition for diagnosis of recurrence of bladder cancer, particularly, non-muscle invasive bladder cancer (NMIBC). Further, according to the present disclosure, it is possible to accurately predict recurrence after surgical tumor removal form a patient with non-muscle invasive bladder cancer, and the present disclosure has an effect of providing information of personalized medicine after surgical tumor removal form a patient with non-muscle invasive bladder cancer.
    Type: Application
    Filed: November 28, 2014
    Publication date: October 1, 2015
    Inventors: Sun-Hee LEEM, Yun-Gil Roh, Tae-Hong Kang
  • Patent number: 7981613
    Abstract: The present invention relates to a kit and a method for diagnosing cancer using polymorphic minisatellites (MS), more specifically, relates to a primer set for detecting polymorphic minisatellites MUC2-MS6 or MUC2-MS7 in the MUC2 gene, a DNA typing kit comprising said primer set, and a kit and a method for diagnosing cancer using a primer set for detecting polymorphic minisatellites MUC2-MS6, MUC2-MS7 or hTERT-VNTR 2-2. According to the present invention, DNA typing of MUC2-MS6 and MUC2-MS7 can effectively achieve the parentage identification, kinship identification or medicolegal examination, because the polymorphic minisatellites MUC2-MS6 and MUC2-MS7 are inherited through meiosis according to Mendelian genetics. In addition, the polymorphic minisatellites MUC2-MS6, MUC2-MS7 and hTERT-VNTR 2-2 can be used to predict and diagnose various cancers; such as gastric cancer, colon cancer, rectal cancer and prostate cancer etc.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: July 19, 2011
    Assignee: Dong-A University Research Foundation for Industry-Academy Corporation
    Inventors: Sun Hee Leem, Yun Hee Jeong, Se Lyun Yoon, So-Young Seol
  • Publication number: 20090269757
    Abstract: The present invention relates to a kit and a method for diagnosing cancer using polymorphic minisatellites (MS), more specifically, relates to a primer set for detecting polymorphic minisatellites MUC2-MS6 or MUC2-MS7 in the MUC2 gene, a DNA typing kit comprising said primer set, and a kit and a method for diagnosing cancer using a primer set for detecting polymorphic minisatellites MUC2-MS6, MUC2-MS7 or hTERT-VNTR 2-2. According to the present invention, DNA typing of MUC2-MS6 and MUC2-MS7 can effectively achieve the parentage identification, kinship identification or medicolegal examination, because the polymorphic minisatellites MUC2-MS6 and MUC2-MS7 are inherited through meiosis according to Mendelian genetics. In addition, the polymorphic minisatellites MUC2-MS6, MUC2-MS7 and hTERT-VNTR 2-2 can be used to predict and diagnose various cancers; such as gastric cancer, colon cancer, rectal cancer and prostate cancer etc.
    Type: Application
    Filed: June 8, 2007
    Publication date: October 29, 2009
    Applicant: DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY ACADEMY COOPERATION
    Inventors: Sun Hee Leem, Yun Hee Jeong, Se Lyun Yoon, So-Young Seol