Abstract: Provided are an isoindolinone derivative compound, a hydrate thereof, a solvate thereof or a pharmaceutically acceptable salt thereof, as caspase inhibitors, which exhibits an excellent interleukin-1?(IL-1?) reducing effect and an excellent apoptosis-reducing effect, thus exhibits excellent activity as a caspase inhibitor, and thus can be used for the prevention or treatment of caspase-related diseases in the medical and pharmaceutical fields.

Abstract: A membrane-electrode assembly and a method for manufacturing the same are provided. The membrane-electrode assembly includes a pattern layer formed between a separator and a subgasket through a UV curing process.

Abstract: A display device includes: a substrate having a first display area and a second display area. A first pixel circuit portion is disposed on the substrate. A first emitting diode includes a first pixel electrode connected to the first pixel circuit portion. A second pixel circuit portion is disposed on a second display area of the substrate. An extension wire is connected to the second pixel circuit portion. A second emitting diode includes a second pixel electrode connected to the extension wire, and a driving circuit portion is connected to the first pixel circuit portion and the second pixel circuit portion, and overlaps the second emitting diode. The extension wire is disposed in a different layer from the second pixel electrode.

Abstract: A memory core characteristic screening method includes the following steps. A command signal transmitting step includes configuring a processing module to transmit a command signal to a memory device. A first internal operating step includes configuring the memory device to operate a first operation to one of a word line, a bit line pair and a column line after a first strobe signal delay time according to a first command. A second internal operating step includes configuring the memory device to operate a second operation to another one of the word line, the bit line pair and the column line after a second strobe signal delay time according to a second command. A memory core characteristic screening step includes screening a memory core characteristic by shorting a timing between the first strobe signal delay time and the second strobe signal delay time.

Abstract: A negative electrode material for a secondary battery includes a matrix containing silicon oxide, a composite oxide of one or more doping elements selected from the group consisting of an alkali metal, an alkaline earth metal, and a post-transition metal, and silicon, or a mixture thereof; and silicon nanoparticles dispersed and embedded in the matrix; wherein a hardness and a Young's modulus measured by a nanoindentation test are 4.0 GPa or more and 40 GPa or more, respectively, and in an X-ray diffraction pattern using a CuK? ray, a ratio (A1/A2) of an area (A1) of a first peak present in a region where a diffraction angle 2? is 10° to 27.4° to an area (A2) of a second peak present in a region where the diffraction angle 2? is 28±0.5° is 0.8 to 6.

Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

Abstract: A power transmission apparatus and a manufacturing method thereof are disclosed. A power transmission apparatus according to an embodiment of the inventive concept includes: a circular rack to which a motor generating power is connected to form an input shaft; a pair of upper pinions gear-engaged with both sides of the circular rack, configured to adjust an assembly distance from the circular rack through a predetermined pinion assembly distance adjuster, and decelerating power received from the circular rack by a reduction ratio of a built-in deceleration structure and transferring decelerated power; a pair of lower pinions respectively one-to-one connected to the pair of upper pinions, and decelerating the power received from the upper pinion by a reduction ratio of a built-in deceleration structure and transferring decelerated power; and a rack/pinion fixing plate to which the circular rack is fixed and to which the pair of upper pinions and the pair of lower pinions are assembled to be movable and fixed.

Abstract: A display device includes a display area including a first display area and a second display area adjacent to each other; a driving circuit, at least part of the driving circuit being disposed in the second display area; first pixel circuit units disposed in the first display area; first light emitting elements disposed in the first display area and electrically connected to the first pixel circuit units; second pixel circuit units disposed in the second display area; second light emitting elements disposed in the second display area and two or more of the second light emitting elements are electrically connected to a second pixel circuit unit; and a light blocking layer overlapping at least one of the second light emitting elements in a plan view.

Abstract: A working robot operating system and method are provided. The system includes a plurality of working robots each configured to perform a work process involving deterioration of a working part and a repair process of repairing the deterioration of the working part. The system also includes a control device configured to determine an existing performance schedule in which the repair process of each of the plurality of working robots is performed based on production information of a product and specification information of a working part for each working robot. The control device is also configured to determine an optimal performance schedule of the repair process for each of the plurality of working robots based on the determined existing performance schedule, and to control the plurality of working robots so that the repair process is performed by following the determined optimal performance schedule.

Abstract: The present invention relates to a novel peptoid derivative and the like. The peptoid derivative is obtained by partially modifying an adiponectin receptor peptide, and has high stability and excellent p-AMPK activity, compared to existing adiponectin receptor peptides and has improved physical properties and activity, thus having the advantage of being suitable for drug formulation. Therefore, the peptoid derivative of the present invention can be used for the prevention or treatment of skin inflammatory diseases, wounds, hair loss, fibrosis, metabolic diseases, or cancer, or the prevention or amelioration of aging, sensitive skin, wrinkles, or moisturization.

Abstract: The present disclosure relates to a novel peptide derivative, etc., the peptide derivative being a partially modified adiponectin receptor peptide which, compared to conventional adiponectin receptor peptides, has higher stability, superior p-AMPK activity, and improved physical properties and activity and thus offers advantages when formulated into a drug. Therefore, the peptide derivative of the present invention can be used to prevent or treat inflammatory skin diseases, wounds, hair loss, fibrosis, metabolic diseases, or cancer, to prevent or alleviate aging, sensitive skin, or wrinkles, or to enhance moisturization.

Abstract: The present disclosure provides: a compound of a specific chemical structure, having excellent activity with respect to BTK degradation; or a pharmaceutically acceptable salt thereof. The present disclosure also provides a composition comprising the compound or pharmaceutically acceptable salts thereof. The present disclosure also provides are pharmaceutical use for treating or preventing BTK-associated diseases (for example, autoimmune diseases or cancer) of the compound, the salt thereof, and the composition comprising same according to the present disclosure. The present disclosure also provides a method for treating or preventing BTK-associated diseases (for example, autoimmune diseases or cancer), comprising administering, to a subject requiring treatment, an effective amount of the compound, the salt thereof, or the composition comprising same according to the present disclosure.

Abstract: An embodiment power conversion device for electric vehicles includes a battery, a relay circuit connected to a charging/discharging outlet through first power lines, a power factor correction circuit connected to the relay circuit through second power lines between the relay circuit and the battery, a discharging outlet connected to branch lines branched from each of the second power lines, and a controller configured to control the relay circuit and the power factor correction circuit such that power from the battery is supplied to a load using asymmetric power or to a load using symmetric power connected to the discharging outlet.

Abstract: A display device includes: a display panel including a first region including a transmissive part configured to transmit light provided from the outside and a second region not including the transmissive part; and a sensor overlapping with the transmissive part, and configured to obtain electrical information based on information provided from the outside, wherein the display panel includes: a thin film transistor layer including a plurality of transistors; a pixel defining layer defining an emission region of a plurality of pixels; and a light blocking layer on the pixel defining layer, and defining the transmissive part, and wherein the pixel defining layer in the first region covers at least a portion of the thin film transistor layer such that light provided through the transmissive part is blocked.

Abstract: A display device includes a display area which includes a first display area including a plurality of first pixels and a second display area including at least one second pixel and at least one light-transmitting portion, a peripheral area disposed around the display area, a data line including a first portion and a second portion spaced apart from each other in a predetermined direction with the light-transmitting portion therebetween, and a conductive pattern disposed at a different conductive layer from the data line. The conductive pattern includes a first pattern portion including a bypass portion that bypasses a periphery of the second display area in a plan view and disposed in the first display area, and the first pattern portion includes a first end electrically connected to the first portion of the data line and a second end electrically connected to the second portion of the data line.

Abstract: The present disclosure relates to a sulfide-based solid electrolyte having a new composition and a new crystal structure.

Abstract: A display device includes a display panel including an antireflection layer on a light emitting element layer which includes a first pixel defining layer in which an opening defining a light emitting area of a first pixel is defined, and a second pixel defining layer in which an opening defining a light emitting area of a second pixel is defined. The antireflection layer includes first and second light blocking layers respectively overlapping the first and second pixel defining layers, and includes a first gap defined by a length of a predetermined direction from an edge of the opening to an edge of an opening of the first light blocking layer, and a second gap defined by a length from an edge of the opening to an edge of an opening of the second light blocking layer in the predetermined direction. The first gap is less than the second gap.

Abstract: A display device includes a substrate, a first display element which is disposed on the substrate, and a plurality of diffraction patterns which are disposed on a path of light emitted from the first display element and arranged along a direction with a first period. when a width of a cross section of one of the plurality of diffraction patterns is defined as a first length, the first period and the first length satisfy Inequality (1): 0.4 ? d ? 1 / DP ? 1 ? 1 , ( 1 ) where DP1 is the first period, and d1 is the first length.