Patents by Inventor Sun Kyung Hwang

Sun Kyung Hwang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7420060
    Abstract: The present invention relates to benzopyran derivatives substituted with a thioxobenzoxazole derivative, or pharmaceutically acceptable salts thereof, processes for preparing the same and a pharmaceutical composition containing the above as an effective ingredient Benzopyran derivatives substituted with thioxobenzoxazole derivatives, represented in <Formula 1>, have the function of protecting heart from ischemia-reperfusion both in vivo and in vitro, so that a pharmaceutical composition containing benzopyran derivatives substituted with thioxobenzoxoazole derivatives or pharmaceutically acceptable salts thereof of the present invention as an effective ingredient can be effectively used for the protection of tissues influenced by ischemia-reperfusion, for example, for the protection of heart, nervous cells, brain, retinal cells, storage organs, etc, and for the treatment of diseases caused by ischemia-reperfusion.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: September 2, 2008
    Assignee: Schaeffler KG
    Inventors: Hong Lim, Dong Ha Lee, Sun Ok Kim, Sung-Eun Yoo, Kyu Yang Yi, Sun Kyung Lee, Jee Hee Suh, Nak Jeong Kim, Sun Kyung Hwang, Tae Mi Kim, Byung Ho Lee, Ho-Won Seo
  • Patent number: 7351843
    Abstract: The present invention relates to furancarbonylguanidine derivatives, a preparation method thereof and a pharmaceutical composition comprising the same. Furancarbonylguanidine derivatives of the present invention inhibit NHE-1 (sodium-hydrogen exchanger isoform 1), which helps recovery of heart function damaged from ischemia/reperfusion and decreases myocardial infarction rate, indicating that they have protective effect on myocardial cells. Thus, furancarbonylguanidine derivatives of the present invention can be effectively used for the prevention and the treatment of ischemic heart diseases such as myocardial infarction, arrhythmia, angina pectoris, etc, and also a promising candidate for a heart protecting agent applied to reperfusion therapy including thrombolytics or cardiac surgery including coronary artery bypass graft, percutaneous transluminal coronary angioplasty, etc.
    Type: Grant
    Filed: December 24, 2004
    Date of Patent: April 1, 2008
    Assignees: Korea Research Institute of Chemical Technology, Yuyu, Inc.
    Inventors: Kyu Yang Yi, Sun Kyung Lee, Nak Jeong Kim, Jee Hee Suh, Soon Hee Hwang, Byung Ho Lee, Ho Won Seo, Sun Kyung Hwang, Sung Eun Yoo, Kyung Hee Lee
  • Patent number: 7309793
    Abstract: The present invention relates to benzopyran derivatives substituted with a benzimidazole derivative, or pharmaceutically acceptable salts thereof, a preparation method of the same and pharmarceutical compositions containing them. Benzopyran derivatives substituted with a benzimidazole derivative, represented in Formula (1), have the function of protecting heart from ischemia-reperfusion without side effect like vasodilation, so that a pharmaceutical composition containing benzopyran derivatives substituted with a benzimidazole derivative or pharmaceutically acceptable salts thereof of the present invention as an effective ingredient can be effectively used for the protection of tissues influenced by ischemia-reperfusion, for example, for the protection of heart, nervous cells, brain, retinal cells, storage organs, etc. and for the treatment of diseases caused by ischemia-reperfusion.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: December 18, 2007
    Assignee: Dongbu Hannong Chemical Co., Ltd.
    Inventors: Hong Lim, Dong Ha Lee, Sun Ok Kim, Sung-Eun Yoo, Kyu Yang Yi, Sun Kyung Lee, Jee Hee Suh, Nak Jeong Kim, Sun Kyung Hwang, Tae Mi Kim, Byung Ho Lee, Ho-Won Seo
  • Patent number: 7279497
    Abstract: The present invention relates to benzopyran derivatives substituted with secondary amines including imidazole, their preparation, and pharmaceutical compositions containing them. The present invention is pharmacologically useful for the treatment of cancer, rheumatoid arthritis, and diabetic retinopathies through anti-angiogenic properties, and also pharmacologically useful in the protection of heart and neuronal cells against ischemia-reperfusion injury or preserving organs.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: October 9, 2007
    Assignee: Korea Research Institute of Chemical Technology
    Inventors: Kyu Yang Yi, Sun Kyung Lee, Sung-Eun Yoo, Jee Hee Suh, Nak Jeong Kim, Sun Kyung Hwang, Byung-Ho Lee, Ho Won Seo, Chong Ock Lee, Sang-Un Choi
  • Publication number: 20070093481
    Abstract: The present invention relates to benzopyran derivatives substituted with a thioxobenzoxazole derivative, or pharmaceutically acceptable salts thereof, processes for preparing the same and a pharmaceutical composition containing the above as an effective ingredient Benzopyran derivatives substituted with thioxobenzoxazole derivatives, represented in <Formula 1>, have the function of protecting heart from ischemia-reperfusion both in vivo and in vitro, so that a pharmaceutical composition containing benzopyran derivatives substituted with thioxobenzoxoazole derivatives or pharmaceutically acceptable salts thereof of the present invention as an effective ingredient can be effectively used for the protection of tissues influenced by ischemia-reperfusion, for example, for the protection of heart, nervous cells, brain, retinal cells, storage organs, etc, and for the treatment of diseases caused by ischemia-reperfusion.
    Type: Application
    Filed: May 28, 2004
    Publication date: April 26, 2007
    Inventor: Sun Kyung Hwang
  • Publication number: 20020019389
    Abstract: The present invention relates to a novel urea derivative represented by the following formula (I), which is useful as an anti-cancer agent: 1
    Type: Application
    Filed: June 14, 2001
    Publication date: February 14, 2002
    Applicant: Chaconne Nsi Co., Ltd.
    Inventors: Joong Young Kim, Byung Hoon Yoon, Sun Kyung Hwang, Chul Min Oh, Mee Seon Park, Kyoung Ok Song, Seong Soo Oh
  • Patent number: 6323238
    Abstract: The present invention relates to novel benzopyranyl guanidine derivatives of the formula 1, process for preparation therof and pharmaceutical use of the benzopyranyl guanidine derivatives. The benzopyranyl guanidine derivatives of the present invention can be used for protecting heart, neuronal cell or brain damage, preserving organs, and also the benzopyranyl guanidine derivatives are pharmacologically useful for inhibiting NO generation, and for suppressing lipid peroxidation, angiogenesis or restenosis. Wherein R1, R2, R3, R4, R5, R6, n and * are each defined in specification.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: November 27, 2001
    Assignee: Dongbu Hannong Chemical Co., Ltd.
    Inventors: Sung-Eun Yoo, Kyu Yang Yi, Sun Kyung Lee, Nak-Jeong Kim, Jee Hee Suh, Young Sook Park, Sun Kyung Hwang, Hwa Sup Shin, Byung Ho Lee, Ho Won Seo, Hong Lim, Sun-Ok Kim, In Sun Cho, Miae Namgoong, Dongsoo Jang