Patents by Inventor Sunanda A. Ranadive

Sunanda A. Ranadive has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6589955
    Abstract: There is provided in accordance with the present invention the quinolone antibacterial gatifloxacin adequately taste-masked so that it can be utilized for pediatric formulations. A crystalline co-precipitate of gatifloxacin and one or both of stearic acid and palmitic acid in a narrow weight ratio has been found to effectively mask the bitter taste of gatifloxacin. The taste of gatifloxacin is effectively masked in the mouth and in aqueous suspension through a full dosage cycle, typically fourteen days. Gatifloxacin in the subject crystalline co-precipitates has been found to be readily available for absorption from the stomach.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: July 8, 2003
    Assignee: Bristol-Myers Squibb Company
    Inventors: Krishnaswamy S. Raghavan, Sunanda A. Ranadive, Kenneth S. Bembenek, Loutfy Benkerrour, Veronique Trognon, Richard G. Corrao, Luigi Esposito
  • Publication number: 20030028025
    Abstract: There is provided in accordance with the present invention the quinolone antibacterial gatifloxacin adequately taste-masked so that it can be utilized for pediatric formulations. A crystalline co-precipitate of gatifloxacin and one or both of stearic acid and palmitic acid in a narrow weight ratio has been found to effectively mask the bitter taste of gatifloxacin. The taste of gatifloxacin is effectively masked in the mouth and in aqueous suspension through a full dosage cycle, typically fourteen days. Gatifloxacin in the subject crystalline co-precipitates has been found to be readily available for absorption from the stomach.
    Type: Application
    Filed: May 9, 2002
    Publication date: February 6, 2003
    Inventors: Krishnaswamy S. Raghavan, Sunanda A. Ranadive, Kenneth S. Bembenek, Loutfy Benkerrour, Veronique Trognon, Richard G. Corrao, Luigi Esposito
  • Patent number: 6413969
    Abstract: There are provided in accordance with the present invention crystalline gatifloxacin pentahydrate represented by the formula in a highly homogeneous form with respect to other crystalline forms thereof.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: July 2, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Krishnaswamy S. Raghavan, Sunanda A. Ranadive, Jack Z. Gougoutas, John D. DiMarco, William L. Parker, Martha Davidovich, Ann Newman
  • Publication number: 20020052379
    Abstract: There are provided in accordance with the present invention crystalline gatifloxacin pentahydrate represented by the formula 1
    Type: Application
    Filed: August 17, 2001
    Publication date: May 2, 2002
    Inventors: Krishnaswamy S. Raghavan, Sunanda A. Ranadive, Jack Z. Gougoutas, John D. DiMarco, William L. Parker, Martha Davidovich, Ann Newman
  • Patent number: 5536507
    Abstract: A three component pharmaceutical formulation of one or more pharmacologically active substances such that greater than 80% of the pharmacologically active substance will be released in the large intestine. The first component comprises the pharmacologically active substance, microcrystalline cellulose, a pH-sensitive polymer, and optionally an osmotic agent. The second component is a delayed release coating, and the third component is an enteric coating.
    Type: Grant
    Filed: June 24, 1994
    Date of Patent: July 16, 1996
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert Abramowitz, Sunanda A. Ranadive, Sailesh A. Varia, Nemichand B. Jain