Abstract: The purpose of the present invention is to provide a chondrocyte culture with high tissue regeneration ability. This purpose is met by a method involving a step in which a cell population separated from cartilage tissue is cultured on a thermoreversible polymer.

Abstract: Provided herein is a sterilizing agent which is edible and/or drinkable after used for sterilization, has an excellent sterilizing effect in a neutral pH range and high safety for a human body, and can be suitably used as a sterilizing agent or an additive for an object such as various liquids, solids, or foods and drinks. The sterilizing agent according to the present invention comprises a strong acidic food additive and a strong alkali salt.

Abstract: A culture method for allowing only cancer cells to grow from a cancerous organ or tissue sample removed surgically or endoscopically, forming a spheroid of cancer cells having a tissue structure and different cell stages similar to a tissue structure and cell stages in the living body, and removing the cultured spheroid of cancer cells from the matrix by changing the temperature within the physiological temperature range.

Abstract: A cell or tissue-culturing carrier which can effectively regenerate an intended a cell or tissue, while suppressing an excessive growth of fibroblasts, and a method of culturing a cell or tissue by using the above carrier, the cell or tissue-culturing carrier wherein fibroblasts showing substantially no growing property in a gel based on the hydrogel-forming polymer, is constituted by using a hydrogel-forming polymer; an aqueous solution of which shows a thermo-reversible sol-gel transition such that it assumes a sol state at a lower temperature and assumes a gel state at a higher temperature.

Abstract: A cell or tissue-culturing carrier which can effectively regenerate an intended a cell or tissue, while suppressing an excessive growth of fibroblasts, and a method of culturing a cell or tissue by using the above carrier, the cell or tissue-culturing carrier wherein fibroblasts showing substantially no growing property in a gel based on the hydrogel-forming polymer, is constituted by using a hydrogel-forming polymer; an aqueous solution of which shows a thermo-reversible sol-gel transition such that it assumes a sol state at a lower temperature and assumes a gel state at a higher temperature.

Abstract: A tissue or organ regeneration material which can easily be placed in a necrotic area or defective space of a tissue or organ in a living body, while suppressing an excessive growth of fibroblasts, to thereby effectively regenerate an intended tissue or organ, and a method of regenerating a tissue or organ by using the above material. The tissue or organ regeneration material wherein fibroblasts shows substantially no growing property in a gel based on the hydrogel-forming polymer is constituted by using a hydrogel-forming polymer, an aqueous solution of which shows a thermo-reversible sol-gel transition such that it assumes a sol state at a lower temperature and assumes a gel state at a higher temperature.

Abstract: Coating materials for biological tissues which make it possible to preserve biological tissues over a long period of time; coated biological tissues with the use of the materials; and a method of coating biological tissues. A biological tissue is coated by using a coating material which contains at least a hydrogel-forming polymer and shows heat-reversible sol/gel transfer, i.e., being in the state of a sol at lower temperatures and setting to gel at higher temperatures. Thus a ratio A2/A0 (wherein A0 represents the cell survival ratio of the biological tissue immediately before the coating, and A2 represents the cell survival ratio of the biological tissue 2 days after the coating) of 20% or more can be easily established.

Abstract: An ion complex which comprises a water-insoluble polyion (P) and a water-soluble polyion (A); and is insoluble in water and soluble in an aqueous organic solvent. Such an ion complex becomes a coating material which can preferably be used for coating of various ionic substances (e.g., substance having biological activity such as an anticoagulant property or an antibacterial property).

Abstract: Ships, outdoor communication equipment (for prevention of ice and snow accretion), devices for body fluid contact or for insertion into living body tissue, etc., are coated by using a coating composition comprising at least, particulates comprising a fluorine-containing polymer and a non-fluorine-containing polymer. There is formed a coating which is excellent in its lubricating property (friction-reducing property) and in its adhesion to the device or in its coating strength.

Abstract: The present invention provides a wound dressing containing macromolecular compounds, wherein said macromolecular compounds comprise multiple blocks having a cloud point and hydrophilic blocks, have a sol-gel transition temperature in aqueous solutions, and indicate a liquid state reversibly at temperatures lower than said sol-gel transition temperature.

Abstract: A wound-covering material is provided which includes at least a polymer having a sol-gel transition temperature in an aqueous solution, shows a substantial water-insolubility at a temperature higher than the sol-gel transition temperature, and shows a reversible water-solubility at a temperature lower than the sol-gel transition temperature. Such a wound-covering material may closely be attached to a wound surface having a complex profile, since it may be placed on the wound surface in a liquid state. In addition, the wound-covering material may provide a wound-covering matter which may rapidly be converted into a gel state due to the temperature of the wound so as to be closely attached to the wound surface and is stably attached to the wound surface in close contact.