Patents by Inventor Sunao Takeshita

Sunao Takeshita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bone-related cadherin-like protein and process for its production
    Patent number: 5869638
    Abstract: A bone-related protein named OSF-4 which is obtained from bone tissue of a mammal including mouse or human, and a process for its production. This protein is a novel naturally occurring mammal protein of the cadherin family.OSF-4 acts as an adhesion molecule or a growth factor which takes part in the process of osteogenesis at the site of bone induction. OSF-4 can be used as an agent for treating bone metabolic diseases, and its high organ specificity for bones enables its use as a diagnostic reagent for bone metabolic diseases.
    Type: Grant
    Filed: October 25, 1996
    Date of Patent: February 9, 1999
    Assignee: Hoechst Japan Limited
    Inventors: Sunao Takeshita, Makoto Okazaki, Shinji Kawai, Atsushi Tsujimura, Egon Amann
  • Protein with bone formation ability and process for its production
    Patent number: 5756664
    Abstract: The present invention provides the sequence of the novel bone-related protein OSF-2 which can be obtained from mammalian bone tissues. The invention further provides a method of production of OSF-2 by recombinant techniques.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: May 26, 1998
    Assignee: Hoechst Japan Limited
    Inventors: Egon Amann, Yoko Otawara-Hamamoto, Reiko Kikuno, Sunao Takeshita, Kenichi Tezuka
  • Bone-related sulfatase-like protein and process for its production
    Patent number: 5627050
    Abstract: A bone-related protein named OSF-8 which is obtained from bone tissue of a mammal including mouse or human, and a process for its production. This protein is a novel naturally occurring mammal protein which belongs to a group of sulfatases. OSF-8 degrades the sulfate groups of the sugar chains of proteoglycan, which makes up the cartilage matrix, during the replacement of cartilage into bone tissue at the stage of osteogenesis. OSF-8 can be used as an agent for treating bone metabolic diseases, and its high organ specificity for bones enables its use as a diagnostic reagent for bone metabolic diseases.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: May 6, 1997
    Assignee: Hoechst Japan Limited
    Inventors: Sunao Takeshita, Toshimi Ito, Yoko Otawara-Hamamoto, Egon Amann
  • Bone-associated transcription control factor-like protein
    Patent number: 5578708
    Abstract: Bone-associated proteins derived from bone of mammals, including mice and human beings, named OSF-6. The protein is the novel natural type mammal protein, which can play an important role in bone formation, and belongs to a group of transcription control factors.OSF-6 can be used as a therapeutic agent for bone metabolic diseases, and also as a diagnostic agent for bone metabolic diseases, since it may demonstrate a high organ specificity to bone.
    Type: Grant
    Filed: March 8, 1994
    Date of Patent: November 26, 1996
    Assignee: Hoechst Japan Limited
    Inventors: Makoto Okazaki, Sunao Takeshita, Shinji Kawai, Reiko Kikuno, Egon Amann
  • Bone-related carboxypeptidase-like protein and process for its production
    Patent number: 5460951
    Abstract: A bone-related carboxypeptidase-like protein named OSF-5 which is obtained from bone tissue of a mammal including mouse or human, and a process for its production. This protein is a novel naturally occurring mammal protein which belongs to a group of carboxypeptidase molecules.OSF-5 acts as an adhesion molecule or a growth factor which takes part in the process of osteogenesis at the site of bone induction. OSF-5 can be used as an agent for treating bone metabolic diseases, and its high organ specificity for bones enables its use as a diagnostic reagent for bone metabolic diseases.
    Type: Grant
    Filed: August 26, 1993
    Date of Patent: October 24, 1995
    Assignee: Hoechst Japan Limited
    Inventors: Shinji Kawai, Sunao Takeshita, Makoto Okazaki, Egon Amann