Abstract: Compounds described herein are inhibitors of retinoic add inducible P450 (CYP26) enzymes, and are useful for treating diseases that are responsive to retinoids. Certain compounds have retinoid activity, are resistant to CYP26-mediated catabolism, and are used for treating diseases that are responsive to retinoids.

Abstract: Compounds described herein are inhibitors of retinoic acid inducible P450 (CYP26) enzymes, and are useful for treating diseases that are responsive to retinoids. Certain compounds have retinoid activity, are resistant to CYP26-mediated catabolism, and are used for treating diseases that are responsive to retinoids.

Abstract: Compounds described herein are inhibitors of retinoic acid inducible P450 (CYP26) enzymes, and are useful for treating diseases that are responsive to retinoids. Certain compounds have retinoid activity, are resistant to CYP26-mediated catabolism, and are used for treating diseases that are responsive to retinoids.

Abstract: Compounds described herein are inhibitors of retinoic acid inducible P450 (CYP26) enzymes, and are useful for treating diseases that are responsive to retinoids. Certain compounds have retinoid activity, are resistant to CYP26-mediated catabolism, and are used for treating diseases that are responsive to retinoids.

Abstract: An event handling system to schedule and translate semantic deductions form Intelligent Agents and sensors into events capable of being made observable by a Recipient system such as monitor that provides a particular view of virtual objects and events is disclosed. The event handling system also encapsulates the system's notion of time. In fact, a human observer can shift the system along the temporal axis (up to the present) in order to replay events, or undertake analyses as a result of speeded-up or slowed-down notions of system time. The event handling system receives events from Clients/Sources via connections through the event handling system Input Portals, and uses Shared Memory as its form of inter-process communication with the Monitors. The event handling system makes events available for a recipient observation sub-system to read and provide their particular view. There can be many Clients and Recipient systems connected to the event handling system at the same time.

Abstract: An event handling system to schedule and translate semantic deductions form Intelligent Agents and sensors into events capable of being made observable by a Recipient system such as monitor that provides a particular view of virtual objects and events is disclosed. The event handling system also encapsulates the system's notion of time. In fact, a human observer can shift the system along the temporal axis (up to the present) in order to replay events, or undertake analyses as a result of speeded-up or slowed-down notions of system time. The event handling system receives events from Clients/Sources via connections through the event handling system Input Portals, and uses Shared Memory as its form of inter-process communication with the Monitors. The event handling system makes events available for a recipient observation sub-system to read and provide their particular view. There can be many Clients and Recipient systems connected to the event handling system at the same time.

Abstract: Geo View is a three-dimensional virtual universe in which a real-world or virtual object may be represented by one or more virtual objects whose attributes are derived from attributes of the real-world object via a flexible user-specifiable mapping. Typically a two-dimensional plane located in three-dimensional space is used to visualize the universe of interest. The placement of virtual objects in the universe typically having a shape is governed by the absolute or relative geographical location of the real-world objects, and also by a flexible set of user-specified layout rules. In addition to the visualisation of various objects, the human observer can attach sounds to objects. The representation of real-world objects with rapidly time-changing attributes may be simplified by the use of Synthetic Strobes, flexible user-specified filters which shift changes in the visual attributes of a shape from one time-domain to another.

Abstract: An observation paradigm that works with a collection of the abovementioned elements, to provide a way of observing information infrastructures and data movement in a chosen time frame. The user (human observer) is provided sophisticated controls and interaction mechanisms that will make it easier for them to detect computer network intrusion and critical security management events in real time as well as allow them to better analyze past events. Embodiments may include various combinations of a framework for “intelligent agents”; an event handling system and a high-performance multi-layer observation facility presenting the user with a semantically dense depiction of an information source under consideration, such as a computer network.

Abstract: An observation sub-system is described wherein in three-dimensional (3D) views of objects and their interactions over time are provided. Each different view is based on a fundamental visualization paradigm. Heavily interacting objects can be depicted as being located “close together”. Rules are created so as to define the position of objects not only from the perspective of whether interaction occurred, but also the amount of interaction, and the rate of interaction. Despite using proximity to show whether an object is interacting with another, further visual mechanisms are used for the user to be able to analyze the type of data interaction, and the current state of affairs of interaction within a specified time slice. There are two types of forces acting on objects in the data view universe, gravitational (as a result of the mass of an object) and electrostatic (as a result of the charge on an object).

Abstract: Data processing architecture comprises one or more data processing components associated with a logical level such that a data processing component associated with a logical level only accepts input from one or more data processing components in a logically higher or lower logical level or an external source; a data processing component associated with a logical level only provides output to one or more data processing components in a logically higher or lower level or an external recipient system. Each data processing component can not accept input or provide output from or to a data processing component in the same logical level; and a data processing component will only accept an input that conforms to an ontology related to the logical level with which the data processing component is associated.

Abstract: Geo View is a three-dimensional virtual universe in which a real-world or virtual object may be represented by one or more virtual objects whose attributes are derived from attributes of the real-world object via a flexible user-specifiable mapping. Typically a two-dmensional plane located in three-dimensional space is used to visualise the universe of interest. The placement of virtual objects in the universe typically having a shape is governed by the absolute or relative geographical location of the real-world objects, and also by a flexible set of user-specified layout rules. In addition to the visualisation of various objects, the human observer can attach sounds to objects. The representation of real-world objects with rapidly time-changing attributes may be simplified by the use of Synthetic Strobes, flexible user-specified filters which changes in the visual attributes of a shape from one time-domain shift to another.

Abstract: An event handling system to schedule and translate semantic deductions form Intelligent Agents and sensors into events capable of being made observable by a Recepient system such as monitor that provides a particular view of virtual objects and events is desclosed. The event handling system also encapsulates the system's notion of time. In fact, a human observer can schift the system along the temporal axis (up to the present) in order to replay events, or undertake analyses as a result of speeded-up or slowed-down notions of system time. The event handling system receives events from Clients/Sources via connections through the event handling system Input Portals, and uses Shared Memory as its form of inter-process communication with the Monitors. The event handling system makes events available for a recipient observation sub-system to read and provide their particular view. There can be many Clients and Recipient systems connected to the event handling system at the same time.

Abstract: An observation sub-system is described wherein in three-dimensional (3D) views of objects and their interactions over time are provided. Each different view is based on a fundamental visualisation paradigm. For example, Data View's location of virtual objects within a space is based on the interaction of real and virtual objects from the environment under examination. DataView, as its name suggests is intended to provide a view where the basic paradigm is simply one of data driven events rather than geographic location. Heavily interacting objects, eg. producers and consumers of data, can be depicted as being located “close together” for example. Therefore, rules are created so as to define the position of objects not only from the perspective of whether interaction occurred, but also the amount of interaction, and the rate of interaction.

Abstract: A system for data processing ad observation having a data processing architecture comprising, one or more data processing components associated with a logical level such that a data processing, component associated with logical level only accepts input from one or more data processing, components in a logically higher or lower logical level or an external source; a data processing component associated with a logical level only provides output to one or more data processing components in a logically higher or lower level or an external recipient system; wherein a data processing component cant not accept input or provide output from or to a data processing component in the same logical level; and a data processing, component will only accept an input that conforms to an ontology related to the logical level with which the data processing, component is associated; one or more external sources that provide data; and in external recipient system for observing one or more human observable virtual objects that are