Abstract: A semiconductor device including a first interlayer insulating film; a conductive pattern in the first interlayer insulating film; a resistance pattern on the conductive pattern; an upper etching stopper film spaced apart from the resistance pattern, extending in parallel with a top surface of the resistance pattern, and including a first metal; a lower etching stopper film on the conductive pattern, extending in parallel with a top surface of the first interlayer insulating film, and including a second metal; and a second interlayer insulating film on the upper etching stopper film and the lower etching stopper film, wherein a distance from a top surface of the second interlayer insulating film to a top surface of the upper etching stopper film is smaller than a distance from the top surface of the second interlayer insulating film to a top surface of the lower etching stopper film.

Abstract: The present invention provides an isolated methyl degron peptide and a fusion protein comprising a methyl degron peptide. Also, the present invention provides screening methods for agents affecting protein lifespan and anti-cancer agents. Moreover, the present invention provides methods of controlling protein lifespan, regulating protein expression, and treating cancers by using a methyl degron peptide or a methyl degron gene.

Abstract: The present invention provides an isolated methyl degron peptide and a fusion protein comprising a methyl degron peptide. Also, the present invention provides screening methods for agents affecting protein lifespan and anti-cancer agents. Moreover, the present invention provides methods of controlling protein lifespan, regulating protein expression, and treating cancers by using a methyl degron peptide or a methyl degron gene.

Abstract: The present invention relates to a method for screening an anticancer agent using ROR?, the method comprising the steps of: culturing cells; bringing a potential substance into contact with the cells; determining whether the phosphorylation level of ROR? in the cells increases as compared to that in control cells (not brought into contact with the potential substance); and selecting the potential substance as an anticancer agent if the phosphorylation level of ROR? in the cells increases.

Abstract: The present invention relates to a method for screening an anticancer agent using ROR?, the method comprising the steps of: culturing cells; bringing a potential substance into contact with the cells; determining whether the phosphorylation level of ROR? in the cells increases as compared to that in control cells (not brought into contact with the potential substance); and selecting the potential substance as an anticancer agent if the phosphorylation level of ROR? in the cells increases.