Abstract: A deformation analysis device for a secondary battery and a non-destructive analysis method by which electrode deformation of a secondary battery may be diagnosed using a computed tomography (CT) image, the method including the steps of obtaining an image by performing computed tomography (CT) on the secondary battery, generating an intensity graph using brightness differences from the image, measuring a core peak FWHM (full width at half maximum) or a core diameter change value from the intensity graph, and determining that the electrode assembly is deformed if the measured core peak FWHM is greater than a peak reference value or the core diameter change value is greater than a diameter reference value.

Abstract: A deformation analysis device and a non-destructive analysis method for a secondary battery are capable of accurately diagnosing electrode deformation of the secondary battery using a computed tomography (CT) image. The deformation analysis method for the secondary battery includes performing computed tomography (CT) scanning on each of a first area and a second area of the secondary battery to acquire a first image corresponding to the first area and a second image corresponding to the second area, measuring a first angle from a winding front end to a winding distal end of an electrode of an electrode assembly in the first image and measuring a second angle from the winding front end to the winding distal end of the electrode of the electrode assembly in the second image, and determining that the electrode assembly is deformed if a difference value between the first angle and the second angle is greater than a reference value.

Abstract: Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a SO2 functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.

Abstract: The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.

Abstract: Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a SO2 functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.

Abstract: Provided are a biodegradable sheet with antiviral properties, a manufacturing method thereof, and the use thereof. The biodegradable sheet comprises: a biodegradable polymer resin consisting of a polylactic acid-based polymer; or a composite degradable polymer resin comprising of a biodegradable resin and a petrochemical resin; and particles of an inorganic antiviral agent or aggregated composite particles of at least two inorganic antiviral agents incorporated into the biodegradable sheet so that the inorganic antiviral agent can be dispersed with a particle size of 100 to 900 nm.

Abstract: The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.

Abstract: Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a SO2 functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.

Abstract: The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-B7-H3 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind B7-H3, as well as methods of making and using these anti-B7-H3 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.

Abstract: Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a —S(?O)(?N—)- functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.

Abstract: Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a SO2 functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.

Abstract: The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.

Abstract: The present invention relates to a compound bearing a self-immolative linker having ?-galactoside-introduced thereto. In a compound bearing a ?-galactoside-introduced self-immolative linker according to the present invention, particularly, the self-immolative linker may form a glycosidic bond with a protein (e.g., an oligopeptide, polypeptide, an antibody, etc.) or ligand which has specific affinity for a desired target or with an active agent (e.g., a drug, a toxin, a ligand, a detection probe, etc.), which has a specific function or activity so as to allow the selective release of the active agent within a target cell.

Abstract: Provided herein are compounds comprising a self-immolative group, and the compounds comprising a self-immolative group according to the present invention may include a protein (for example, an oligopeptide, a polypeptide, an antibody, or the like) having substrate-specificity for a target and an active agent (for example, a drug, a toxin, a ligand, a detection probe, or the like) having a specific function or activity.

Abstract: Provided herein are compounds comprising a self-immolative group, and the compounds comprising a self-immolative group according to the present invention may include a protein (for example, an oligopeptide, a polypeptide, an antibody, or the like) having substrate-specificity for a target and an active agent (for example, a drug, a toxin, a ligand, a detection probe, or the like) having a specific function or activity.

Abstract: The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.

Abstract: The present invention relates to a compound bearing a self-immolative linker having ?-galactoside-introduced thereto. In a compound bearing a ?-galactoside-introduced self-immolative linker according to the present invention, particularly, the self-immolative linker may form a glycosidic bond with a protein (e.g., an oligopeptide, polypeptide, an antibody, etc.) or ligand which has specific affinity for a desired target or with an active agent (e.g., a drug, a toxin, a ligand, a detection probe, etc.), which has a specific function or activity so as to allow the selective release of the active agent within a target cell.

Abstract: Provided are compounds comprising a self-immolative group, and the compounds comprising a self-immolative group according to the present invention may include a protein (for example, an oligopeptide, a polypeptide, an antibody, or the like) having substrate-specificity for a target and an active agent (for example, a drug, a toxin, a ligand, a detection probe, or the like) having a specific function or activity.

Abstract: Provided are compounds comprising a self-immolative group, and the compounds comprising a self-immolative group according to the present invention may include a protein (for example, an oligopeptide, a polypeptide, an antibody, or the like) having substrate-specificity for a target and an active agent (for example, a drug, a toxin, a ligand, a detection probe, or the like) having a specific function or activity.