Abstract: The present invention relates to a pharmaceutical composition containing ?-lapachone as an active ingredient for prevention or treatment of cholestatic liver disease, and can provide agents for effectively preventing and treating cholestatic liver disease.

Abstract: Disclosed is a copolymer including a first part including an aromatic vinyl-based monomer and a conjugated diene-based monomer; and a second part including an aromatic vinyl-based monomer and a conjugated diene-based monomer, wherein the content of the aromatic vinyl-based monomer is 35 to 45% by weight based on a total weight of the copolymer, and the copolymer satisfies Equation 1 below: V1>V2??<Equation 1> wherein V1 is a vinyl content in the first part, and V2 is a vinyl content in the second part.

Abstract: The present invention relates to a salivary gland therapeutic agent using the effects of a cell-derived vesicle of enhancing the proliferation capacity of salivary gland cells, promoting an amylase activity, and enhancing transepithelial resistance. A pharmaceutical composition comprising the cell-derived vesicle according to the present invention has the effects of enhancing the proliferation capacity of salivary gland cells damaged by radiation, promoting amylase activity, increasing transepithelial resistance, enhancing the expression of Aquaporin 5, and increasing the amount of saliva secretion. Therefore, the pharmaceutical composition comprising the cell-derived vesicle of the present invention can be used for preventing and treating salivary gland diseases, and thus can be widely used in the pharmaceutical industry and health functional food field.

Abstract: Disclosed is a copolymer including a first part including an aromatic vinyl-based monomer and a conjugated diene-based monomer; and a second part including an aromatic vinyl-based monomer and a conjugated diene-based monomer, wherein the content of the aromatic vinyl-based monomer is 35 to 45% by weight based on a total weight of the copolymer, and the copolymer satisfies Equation 1 below: V1>V2 ??<Equation 1> wherein V1 is a vinyl content in the first part, and V2 is a vinyl content in the second part.

Abstract: The present invention relates to a method for preparing neodymium-carbon-nanotube and a process for preparing 1,4-cis-polybutadiene utilizing the same and more particularly, neodymium-carbon-nanotube. Neodymium is introduced by coordination with carboxylic acid, which is formed on the surface of carbon nanotube. In 1,3-butadiene polymerization with the neodymium-catalyst comprising the neodymium-carbon nanotube, a particular halogen compound, and a particular organometallic compound in an appropriate ratio, high 1,4-cis polybutadiene having molecular weight of 10,000 to 2,000,000 is produced, which exhibits excellent mechanical properties such as elasticity and durability.