Abstract: The present disclosure relates to the detection of beta amyloid protein as an Alzheimer's disease-causing factor in the palatine tonsil and a use thereof and, more specifically, to the diagnosis of Alzheimer's disease by identifying the expression of beta amyloid and/or Staphylococcus aureus in a tonsillar sample. The present disclosure can diagnose Alzheimer's disease through the expression of beta amyloid and/or Staphylococcus aureus in a palatine tonsil tissue and, furthermore, can be very advantageously used for revealing the pathogenesis of Alzheimer's disease and for treating Alzheimer's disease.

Abstract: A thermal-analysis-based output stabilization method and system for improving 3D printing output reliability are provided. The thermal-analysis-based output stabilization method according to an embodiment of the present invention comprises steps in which: an output stabilization system performs first stacking thermal analysis on a plurality of residual heat quantity review specimens for which a process range corresponding to normal output quality is set; the output stabilization system performs second stacking thermal analysis on an actual stacked product on the basis of the first stacking thermal analysis result in the same manner as the first stacking thermal analysis method; and the output stabilization system performs stability review on the stacking result of the stacked product on the basis of the second stacking thermal analysis result.

Abstract: Provided are a method and a system for determining a model output direction on the basis of heat dissipation characteristic analysis for stabilizing output of metal 3D printing.

Abstract: A method and a system for providing a domain-based process framework are provided. The method for providing a domain-specific process framework, according to one embodiment of the present invention, comprises steps in which: a process framework provision system generates a process model on the basis of a pre-stored meta-model (primitive) and a relationship model (relation); and the process framework provision system distributes the generated process model. Therefore, a process framework capable of reflecting domain knowledge is introduced so that different business processes between companies can be normalized by domain.

Abstract: Provided is a method for regenerating a tool path on the basis of output data feedback in order to improve 3D printing output reliability. A tool path regeneration system according to an embodiment of the present invention comprises: a slicing unit for configuring a process parameter for 3D printing and performing slicing for 3D model data on the basis of the configured process parameter to generate a job file; and an output unit for performing 3D printing on the basis of the generated job file and collecting output data that is output while the 3D printing is performed, wherein the slicing unit comprises an output data analysis module for performing monitoring on the basis of the output data received from the output unit and determining whether to correct the process parameter on the basis of the result of the monitoring.

Abstract: Provided is a method for modifying a design on the basis of an additive cross-section outline for 3D printing of an additive manufacturing method. The method for modifying a design on the basis of an additive cross-section outline according to an embodiment of the present invention comprises the steps of: slicing a 3D model into a plurality of 2D layers; calculating a difference region between a first layer and a second layer that is a lower layer adjacent to the first layer; calculating a modified outline that minimizes a region required for support by reducing the outline of the difference region; and merging the modified outline and the outline of the second layer.

Abstract: Provided is a method for generating an auxiliary support for 3D printing output stability in bottom-up stacking manufacturing. The method for generating an auxiliary support, according to an embodiment of the present invention, comprises the steps of: slicing a 3D model into a plurality of 2D layers; calculating the position of an auxiliary support on the basis of the width of the sliced 2D layers; and generating an auxiliary support on the basis of the calculation result. Therefore, output stability can be increased by automatically generating the position and size of the auxiliary support so that the separation force of a stacked surface is uniform.

Abstract: Provided is a method for generating a hollow structure of a 3D model on the basis of a 2D laminated cross-sectional outline to reduce the amount of using a material or the weight of a printed matter during laminating and manufacturing. The method for generating a hollow structure based on a 2D laminated cross-sectional outline, according to an embodiment of the present invention, comprises the steps of: slicing the 3D model; generating a hollow structure outline on the basis of the result of the slicing; detecting an overhang area between adjacent hollow structure outlines; recalculating the hollow structure outline according to the result of detecting the overhang area; and generating a hollow structure mesh on the basis of the recalculated hollow structure outline. Accordingly, because 2D laminated cross-sectional data is used, a hollow structure can be generated without separate data processing, thereby reducing a calculation burden.

Abstract: Provided are a method and a system for solving a tolerance problem which may occur in a slicing quantization (staircase effect) process of 3D printing which slices a 3D model and laminates layers one by one. According to an embodiment of the present disclosure, a 3D model slicing method includes the steps of: receiving, by a 3D model slicing system, an input of data of a 3D model to 3D print; examining, by the 3D model slicing system, a dimension of a layer thickness of the inputted 3D model; correcting, by the 3D model slicing system, a size of a layer for slicing, based on a result of the examining; and slicing, by the 3D model slicing system, the corrected 3D model. Accordingly, by preserving a dimension within a layer thickness, a problem that a concavo-convex portion is lost in a slicing quantization process of 3D printing according to a slicing position within a layer thickness, and a tolerance occurs is solved.

Abstract: Provided is a tool path optimization method for minimizing thermal unbalance in metal 3D printing. The tool path optimization method according to an embodiment of the present disclosure includes: a slicing step of generating stratum data by slicing a 3D model; a tool path data generation step of generating tool path data including a moving path of a tool which is moved inside a stratum, by applying equipment settings to the generated stratum data; a thermal data generation step of generating thermal data A of a first stratum and thermal data B1, B2, B3 of three lower layers of the first stratum, based on the tool path data; a thermal data analysis step of generating a thermal data contour by combining the thermal data A, B1, B2, B3; a thermal data application step of identifying an area where thermal unbalance is concentrated based on the thermal data contour, and setting an identification area D; and a tool path optimization step of optimizing a tool path for the identification area D.

Abstract: A method for producing a support structure of a 3D model for 3D printing is provided. A method for producing a support according to an embodiment of the present invention comprises the steps of: dividing a surface constituting a 3D model into multiple surface patches; classifying respective divided surface patches according to geometric characteristics; and producing supports corresponding to the classified characteristics with regard to respective surface patches. Accordingly, during metal laminate manufacturing, the output stability may be improved while reducing the support producing process time. In addition, the surfaces may be expressed by different colors according to the result of geometric characteristic classification, and the supports may also be expressed by different colors according to the type, thereby playing the role of guide lines such that the user can recognize the shape of the surfaces and the type of supports to be installed on the corresponding surfaces.

Abstract: Provided is a method for monitoring 3D printing equipped with a 3D printing slicer and a recursive loop structure. A 3D printing method according to an embodiment of the present invention sets up a slicing environment for 3D printing of a 3D model, generates a mechanical code by performing slicing according to the setup environment, monitors the status of the 3D printing according to the generated mechanical code, and, depending on the monitoring result, determines whether or not to re-perform the setup and subsequent steps. Accordingly, by semi- or fully automating the 3D printing engineering process, the time and effort for engineering performance involving human participation are reduced, and the human resource is concentrated on a more important area, such that the effects of enhancing the 3D printing output quality and assuring the quality can be expected.

Abstract: Provided is a slicing 2D data-based pattern application method for generating an output code in which the inside of a model is filled with a pattern, so as to reduce a binder usage amount and maintain a strength and a shape in sand binder jetting additive manufacturing. A slicing 2D data-based pattern application method according to an embodiment of the present invention comprises the steps of: generating 2D data by slicing an output model; generating an inner pattern in at least one of layers forming an output model in consideration of the set thickness of the layers and the outer thickness thereof and generating an output code by applying the generated inner pattern. Therefore, the cost of producing an additive manufacturing output can be reduced by reducing the binder usage amount through the application of the inner pattern.

Abstract: Provided is a nozzle clogging defect compensating method for compensating for a nozzle clogging defect appearing in a binder jetting stack manufacturing means. The nozzle clogging defect compensating method according to an embodiment of the present invention comprises the steps of: determining a defect occurrence region when a clogging defect of a nozzle used in the binder jetting stack manufacturing means occurs; determining whether compensation for the detect occurrence region is possible; when the compensation is possible, generating defect information and reflecting the defect information in an output code; setting a defect compensation region on the basis of the defect information; determining a defect compensation type of the defect compensation region; and reflecting a result of the determining in the output code.

Abstract: Provided is a method for generating a hollow structure of a 3D model on the basis of a 2D laminated cross-sectional outline to reduce the amount of using a material or the weight of a printed matter during laminating and manufacturing. The method for generating a hollow structure based on a 2D laminated cross-sectional outline, according to an embodiment of the present invention, comprises the steps of: slicing the 3D model; generating a hollow structure outline on the basis of the result of the slicing; detecting an overhang area between adjacent hollow structure outlines; recalculating the hollow structure outline according to the result of detecting the overhang area; and generating a hollow structure mesh on the basis of the recalculated hollow structure outline. Accordingly, because 2D laminated cross-sectional data is used, a hollow structure can be generated without separate data processing, thereby reducing a calculation burden.

Abstract: Provided is a 3D printing slicing method for solving a quantization error problem. A 3D model slicing method according to an embodiment of the present invention comprises: receiving, as input, data of a 3D model to be three-dimensionally printed; calculating the height of the input 3D model; revising the height of the 3D model on the basis of a result of the calculation; and slicing the 3D model having the revised height. Accordingly, the present invention can easily and reliably solve a slicing quantization error problem even without changing the lamination thickness of a 3D printer.

Abstract: Provided is a method for creating a 2D slicing polyline based support structure for 3D printing. A method for creating a support structure according to an embodiment of die present invention comprises: slicing a 3D model into a plurality of 2D layers; comparing the 2D layers to calculate a support position for each of the 2D layers; and creating supports at the calculated positions. As a result, the supports can be created at precise and meaningful positions, a stable output is possible, and additional slicing work is not necessary on the created supports, whereby improvement of speed can be expected.

Abstract: A method for producing a support structure of a 3D model for 3D printing is provided. A method for producing a support according to an embodiment of the present invention comprises the steps of: dividing a surface constituting a 3D model into multiple surface patches; classifying respective divided surface patches according to geometric characteristics; and producing supports corresponding to the classified characteristics with regard to respective surface patches. Accordingly, during metal laminate manufacturing, the output stability may be improved while reducing the support producing process time. In addition, the surfaces may be expressed by different colors according to the result of geometric characteristic classification, and the supports may also be expressed by different colors according to the type, thereby playing the role of guide lines such that the user can recognize the shape of the surfaces and the type of supports to be installed on the corresponding surfaces.

Abstract: Provided is a method for monitoring 3D printing equipped with a 3D printing slicer and a recursive loop structure. A 3D printing method according to an embodiment of the present invention sets up a slicing environment for 3D printing of a 3D model, generates a mechanical code by performing slicing according to the setup environment, monitors the status of the 3D printing according to the generated mechanical code, and, depending on the monitoring result, determines whether or not to re-perform the setup and subsequent steps. Accordingly, by semi- or fully automating the 3D printing engineering process, the time and effort for engineering performance involving human participation are reduced, and the human resource is concentrated on a more important area, such that the effects of enhancing the 3D printing output quality and assuring the quality can be expected.