Abstract: The present invention relates to a pharmaceutical composition containing a SIRT2 inhibitor and, more specifically, to: a pharmaceutical composition for preventing or treating renal inflammatory diseases, which are caused by sepsis, by controlling inflammation-inducing factors by sepsis through the regulation of SIRT2 gene expression so as to reduce renal inflammation, thereby preventing a kidney injury; and a pharmaceutical composition for preventing or treating cancer, having an effect of increasing anticancer efficacy while reducing nephrotoxicity, which is a side effect of cisplatin, when administered together with cisplatin.

Abstract: Disclosed is a digital X-ray image detector using an FED, including an upper substrate and a lower substrate disposed to face each other; an anode formed beneath the upper substrate; a photoconductive layer formed beneath the anode for forming electron-hole pairs using X-rays; a cathode formed on the lower substrate; an emitter formed on the cathode for emitting electrons of the cathode; a gate electrode formed on an insulating layer provided around the emitter on the cathode; and a data processing part for converting information about the electron-hole pairs formed in the photoconductive layer by the X-rays, transferred from the anode, to digital data through signal processing including filtering, amplification, storage, or A/D conversion. The high performance digital X-ray image detector of this invention has a high image resolution and a large area, is easy to manufacture and process compared to conventional processes, and has excellent detection efficiency of electrical signals.

Abstract: The present invention relates to a pharmaceutical composition containing ?-lipoic acid (LA) as an active ingredient. ?-lipoic acid is an inhibitor of fractalkine expression, and exhibits effects of alleviating inflammation due to endotoxemia by decreasing expression of fractalkine and attachment of endothelial cells to monocytes in endothelial cells of an LPS-induced endotoxemia model.

Abstract: Disclosed is a digital X-ray image detector using an FED, including an upper substrate and a lower substrate disposed to face each other; an anode formed beneath the upper substrate; a photoconductive layer formed beneath the anode for forming electron-hole pairs using X-rays; a cathode formed on the lower substrate; an emitter formed on the cathode for emitting electrons of the cathode; a gate electrode formed on an insulating layer provided around the emitter on the cathode; and a data processing part for converting information about the electron-hole pairs formed in the photoconductive layer by the X-rays, transferred from the anode, to digital data through signal processing including filtering, amplification, storage, or A/D conversion. The high performance digital X-ray image detector of this invention has a high image resolution and a large area, is easy to manufacture and process compared to conventional processes, and has excellent detection efficiency of electrical signals.

Abstract: The present invention relates to a pharmaceutical composition containing ?-lipoic acid (LA) as an active ingredient. ?-lipoic acid is an inhibitor of fractalkine expression, and exhibits effects of alleviating inflammation due to endotoxemia by decreasing expression of fractalkine and attachment of endothelial cells to monocytes in endothelial cells of an LPS-induced endotoxemia model.