Abstract: Provided is a composition for preventing and treating a menopausal disorder containing extracts of Dendropanax morbifera LEV. as an active ingredient. Specifically, the extracts of Dendropanax morbifera LEV. exhibit a significant ER agonist activity within a cell, and exhibit a very potent ER agonist (full agonist) activity with an EC50 value of about 100 ?g/ml. Thus, the extracts of Dendropanax morbifera LEV. comprising a high content of plant metabolites similar to estrogen can be useful as hormone replacement therapy capable of improving various symptoms derived from a deficiency of estrogen in menopausal women.

Abstract: This invention relates to a bipolar plate for a fuel cell having a controlled structure of carbon materials and a method of manufacturing the same, the method including obtaining a masterbatch by mixing a first carbon material powder having a size ranging from 0.1 to 200 ?m with a polymer resin, forming a masterbatch powder by crushing the masterbatch, preparing a conductive composition by mixing the masterbatch powder with a second carbon material powder having a size ranging from 300 ?m to 1 mm, and manufacturing a bipolar plate by subjecting the conductive composition to compression molding. Thereby, carbon materials in a powder phase having different sizes can be uniformly dispersed via a masterbatch to thus shorten a conductive path, thereby decreasing electrical resistivity, and furthermore, dispersion in the polymer resin can be improved, thereby increasing flexural strength.

Abstract: Provided is a composition for preventing and treating a menopausal disorder containing extracts of Dendropanax morbifera LEV. as an active ingredient. Specifically, the extracts of Dendropanax morbifera LEV. exhibit a significant ER agonist activity within a cell, and exhibit a very potent ER agonist (full agonist) activity with an EC50 value of about 100 ?g/ml. Thus, the extracts of Dendropanax morbifera LEV. comprising a high content of plant metabolites similar to estrogen can be useful as hormone replacement therapy capable of improving various symptoms derived from a deficiency of estrogen in menopausal women.