Abstract: The present disclosure relates to an insertion type drug injection device capable of being inserted into a body for injecting a drug into a skin, including: a main body having an open insert part and formed in a tubular shape having a hollow space therein, a needle assembly formed in the insert part, provided with a plurality of needles, and including a pneumatic port and a drug injection port, and a drug injection pipe inserted into the main body and connected to a drug injection port of the needle assembly, and an air flowing pipe connected to the pneumatic port.

Abstract: The present disclosure relates to an insertion type drug injection device capable of being inserted into a body for injecting a drug into a skin, including: a main body having an open insert part and formed in a tubular shape having a hollow space therein, a needle assembly formed in the insert part, provided with a plurality of needles, and including a pneumatic port and a drug injection port, and a drug injection pipe inserted into the main body and connected to a drug injection port of the needle assembly, and an air flowing pipe connected to the pneumatic port.

Abstract: A multi-needle assembly for cosmetic procedure includes a main body having an inner space extending from one end to another, a reciprocating member provided in the main body, a needle member placed into the reciprocating member and having a plurality of needles that enter or exit through the one end of the main body, a guide suction into or from which the plurality of needles enter or exit, and length adjusting grooves for moving the reciprocating member in a forward and backward direction.

Abstract: A multi-function device for skin treatment is provided, which includes: a main body comprising a lower base, a cover coupled to an upper portion of the lower base, and a main case seated on the lower base; an IPL generator comprising: an IPL power unit comprising a main power case mounted on the main case, and a main power board housed in the main power case; an IPL coolant circulation device mounted on the main case; and an IPL connector attached to the main case, and coupled to: an IPL connection cable; a vacuum suction unit connected to an IPL handpiece and generating vacuum suction pressure; a suction cable connected to the vacuum suction unit; and a coolant connection cable connected to the IPL coolant circulation device; an IPL handpiece connected to the IPL connection cable and performing IPL treatment while being in contact with skin; a high frequency generator comprising a high frequency control board mounted on other side of the main case, and a high frequency power connected to the high frequency c

Abstract: A multi-needle assembly for cosmetic procedure includes a main body having an inner space extending from one to the other ends, a reciprocating member provided in the main body to be moved along an inner circumferential surface of the main body in a forward and backward direction, a needle member placed into the reciprocating member 4 and coupled therein, and having a plurality of needles that enter or exit through one end of the main body, a guide suction into or from which the plurality of needles enter or exit, in which the guide suction comprises an opening to be brought into contact with a skin and forms a suction force for sucking in foreign matter from inside while the opening is in close contact with the skin, and a length adjusting means for moving the reciprocating member in a forward and backward direction along a spiral groove and a slide groove formed in the inner circumferential surface of the main body to adjust a projecting length of the needles.

Abstract: The present invention uses an injection apparatus comprising: an injector which includes a mounting part on which a syringe is mounted, a needle assembly having a plurality of needles, a motor and a screw for actuating a piston of the syringe forward and backward; and a main body for controlling the forward and backward actuation of the piston of the syringe and drug injection. The present invention is configured as follows: a vacuum suction pressure is formed in the needle assembly that is in contact with the skin; injection is performed so that a drug is injected through a needle after it is determined that the needle is in close contact with the skin by comparing a sensed vacuum suction pressure value with a preset vacuum suction pressure value; and if injection is completed, the needle assembly is separated from the skin.

Abstract: A high frequency handpiece for skin treatment is provided, which includes: a handle of which one end is connected to a high frequency generator and the other end has an opening formed thereon, in which the handle has a cylindrical shape to allow grip by hand; and a needle cartridge fitted to one side of the handle and including a needle formed thereon to output a high frequency to skin when supplied with power, in which the needle cartridge includes a holder having both open sides and a passage formed therein; a needle assembly coupled to one side of the holder and having the needle formed therein to be inserted into the skin; a connector coupled to an opening on the other side of the holder, connected to one side of the needle assembly, and having a fitting part formed at the other side; and a power plug removably fitted into the fitting part of the connector and is coupled to the handle to supply power.

Abstract: A multi-function device for skin treatment is provided, which includes: a main body comprising a lower base, a cover coupled to an upper portion of the lower base, and a main case seated on the lower base; an IPL generator comprising: an IPL power unit comprising a main power case mounted on the main case, and a main power board housed in the main power case; an IPL coolant circulation device mounted on the main case; and an IPL connector attached to the main case, and coupled to: an IPL connection cable; a vacuum suction unit connected to an IPL handpiece and generating vacuum suction pressure; a suction cable connected to the vacuum suction unit; and a coolant connection cable connected to the IPL coolant circulation device; an IPL handpiece connected to the IPL connection cable and performing IPL treatment while being in contact with skin; a high frequency generator comprising a high frequency control board mounted on other side of the main case, and a high frequency power connected to the high frequency c

Abstract: The present invention uses an injection apparatus comprising: an injector which includes a mounting part on which a syringe is mounted, a needle assembly having a plurality of needles, a motor and a screw for actuating a piston of the syringe forward and backward; and a main body for controlling the forward and backward actuation of the piston of the syringe and drug injection. The present invention is configured as follows: a vacuum suction pressure is formed in the needle assembly that is in contact with the skin; injection is performed so that a drug is injected through a needle after it is determined that the needle is in close contact with the skin by comparing a sensed vacuum suction pressure value with a preset vacuum suction pressure value; and if injection is completed, the needle assembly is separated from the skin.

Abstract: A syringe device for skin treatment is provided, which includes a syringe for injecting a drug into a skin through a needled at an end, a syringe seat connected with a cylinder of the syringe receiving the drug therein to allow a reciprocation of the cylinder within a limited range according to a direction of injecting the drug, a mount formed on the syringe seat and to which the cylinder of the syringe is fixed, an injector mounted on one side of the syringe seat to be rotated by a driving force to move in association with movement of the syringe seat to move a rod of the cylinder toward a needle, and a controller mounted on one sides of the syringe seat and the injector to operate the injector when the needle is in contact with the skin and the syringe seat is moved to one end within a limited range, and stop the injector when the needle is apart from the skin and the syringe seat is moved to opposite end within the limited range.

Abstract: A syringe device for skin treatment is provided, which includes a syringe for injecting a drug into a skin through a needled at an end, a syringe seat connected with a cylinder of the syringe receiving the drug therein to allow a reciprocation of the cylinder within a limited range according to a direction of injecting the drug, a mount formed on the syringe seat and to which the cylinder of the syringe is fixed, an injector mounted on one side of the syringe seat to be rotated by a driving force to move in association with movement of the syringe seat to move a rod of the cylinder toward a needle, and a controller mounted on one sides of the syringe seat and the injector to operate the injector when the needle is in contact with the skin and the syringe seat is moved to one end within a limited range, and stop the injector when the needle is apart from the skin and the syringe seat is moved to opposite end within the limited range.

Abstract: The present invention relates to a method for preparing a purified extract of Lonicera Japonica THUNBERG and the composition comprising the same for preventing and treating sepsis and septic shock. The purified extract of purified extract of Lonicera Japonica THUNBERG potent antisepsis activity in severe sepsis CLP model test, the effect on MODS, and the inhibitory effect on various pro-inflammatory cytokines such as TNF-alpha, IL-1beta, IFN-gamma, HMGB-1 etc, as well as it showed unexpectedly synergistic effect on the treatment of sepsis and septic shock in case of combining with the commercially available anti-septic agent such as broad-spectrum anti-biotic to the person skilled in the art, therefore, it can be useful in treating and preventing the sepsis and septic shock as a medicament and health functional food.

Abstract: The present invention relates to a method that improves productivity of a useful secondary metabolite by eliminating biological by-products effectively during the culture of a useful secondary metabolite-producing microorganism, and more particularly, in order to efficiently eliminate biological by-products formed during the culture of Sorangium cellulosum, the present invention relates to a method for producing epothilones comprising that a cation exchange resin is added to said culture medium or said culture broth is recirculated through a column charged with a cation exchange resin.