Abstract: Novel semi-synthetic cephalosporin derivatives having a fused pyridiniummethyl at 3-position of the cephem nucleus, pharmaceutically acceptable salts, physiologically hydrolizable esters or solvates thereof are disclosed. Also disclosed is a process for preparing the cephalosporin derivatives which comprises introducing a fused pyridiniummethyl substituent at 3-position of 7-.beta.-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-cephem-ca rboxylic acid derivatives. The compounds of the present invention show potent antibacterial activities and a broad spectrum against both gram-positive and gram-negative bacteria.

Abstract: A high dielectric ceramic composition essentially consisting of 97.04 weight % to 97.80 weight % of BaTiO.sub.3 as a host material, 1.42 weight % to 1.92 weight % of Nb.sub.2 O.sub.5, 0.04 weight % to 0.06 weight % of MnO.sub.2 0.33 weight % to 0.45 weight % of CoO, 0.31 weight % to 0.41 weight % of CeO.sub.2 and 0.10 weight % to 0.12 weight % of ZnO. The composition exhibits TCC characteristic satisfying the characteristic of X7R of EIA standard, high dielectric constant of 3,200 to 3,800 and high insulation resistivity of 10.sup.3 to 10.sup.14. With these characteristics, the composition is useful for making multi-layer ceramic capacitors, thereby contributing to a compactness of electronic/electric appliances.