Patents by Inventor Sung Yang
Sung Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12492363Abstract: The present disclosure relates to a herringbone-type fluid guiding unit and an apparatus for concentrating fluid using same. The herring-bone type fluid guiding unit includes: a front member formed on a flow path and formed so that the width between the left side and the right side widens from a front end part toward the back, with respect to the flow direction of a fluid; and a rear member extending from the front member toward the back, wherein the rear member is provided with a recessed part that is recessed to a specific depth from the rear edge toward the front or with a protruding part that protrudes toward the back.Type: GrantFiled: July 24, 2019Date of Patent: December 9, 2025Assignee: GIST(Gwangju Institute of Science and Technology)Inventors: Sung Yang, Ji Chul Hyun
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Patent number: 12492364Abstract: The present disclosure relates to a herringbone-type fluid guiding unit and an apparatus for concentrating fluid using same. The herring-bone type fluid guiding unit includes: a front member formed on a flow path and formed so that the width between the left side and the right side widens from a front end part toward the back, with respect to the flow direction of a fluid; and a rear member extending from the front member toward the back, wherein the rear member is provided with a recessed part that is recessed to a specific depth from the rear edge toward the front or with a protruding part that protrudes toward the back.Type: GrantFiled: July 12, 2022Date of Patent: December 9, 2025Assignee: GIST(Gwangju Institute of Science and Technology)Inventors: Sung Yang, Ji Chul Hyun
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Publication number: 20250345798Abstract: The present disclosure relates to a microfluidic device that enables rapid high-throughput separation because it can separate particles in a fluid on the basis of their sizes through a simple method of passing a fluid without using external forces such as electric force, magnetic force, and acoustic radiation force.Type: ApplicationFiled: May 8, 2025Publication date: November 13, 2025Applicant: GIST(Gwangju Institute of Science and Technology)Inventors: Sung Hoon BAE, Sung YANG, Ye Sung LEE
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Patent number: 12196747Abstract: The present invention relates to a multi-microorganism detection system, and more particularly, to a multi-microorganism detection system using a dielectrophoresis force. Provided is a rapid and accurate multi-microorganism detection system. Microorganisms are concentrated at a high throughput using DEP after synthesizing the microorganisms and fluorescent magnetic particles, and when a complex in which the fluorescent magnetic particles are bound to the microorganisms passes through a detection unit by moving only the microorganisms to the detection unit after separating the magnetic particles from the complex (i.e., the microorganisms to which the magnetic particles are bound) using a DEP force, a fluorescence signal of a specific wavelength band is generated according to the type of the fluorescent magnetic particle and the concentration of the microorganisms according to the type of microorganism is measured by measuring and analyzing the fluorescence signal.Type: GrantFiled: August 16, 2021Date of Patent: January 14, 2025Assignee: GIST(Gwangju Institute of Science and Technology)Inventors: Sung Yang, Young Ran Yun, Taek Eon Jeong
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Publication number: 20240377356Abstract: The present disclosure relates to a microbial concentration detection element in an unknown solution. In more detail, the microbial concentration detection element includes: a preprocessing unit configured to produce a microbe substitution solution by transferring microbes in an unknown solution containing detection target microbes into a reference solution through acoustophoresis, and to calculate electrical property information of the microbe substitution solution; and a microbe concentration measurement unit configured to separate the microbe substitution solution into a microbe concentration solution and a filtered solution through dielectrophoresis on the basis of the electrical property information measured by the preprocessing unit, and then measure a microbial concentration of the microbe concentration solution.Type: ApplicationFiled: July 23, 2024Publication date: November 14, 2024Applicant: GIST(Gwangju Institute of Science and Technology)Inventors: Sung YANG, Ye Sung LEE, Soo Sung KIM
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Patent number: 12140562Abstract: The present disclosure relates to a microorganism detection apparatus using a dielectrophoresis (DEP) force. A microorganism detection apparatus according to one embodiment of the present disclosure may include a detection unit that detects microbial particles using a DEP force corresponding to latex particles combined with the microbial particles.Type: GrantFiled: July 20, 2021Date of Patent: November 12, 2024Assignee: GIST(Gwangju Institute of Science and Technology)Inventors: Sung Yang, Taek Eon Jeong, Jae Hyeon Ahn, Yu Gyung Jung
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Patent number: 12038399Abstract: An apparatus for analyzing a biological material component may include an impedance sensor comprising a first electrode having a first contact surface that contacts an analysis target, and a second electrode having a second contact surface that contacts the analysis target and that faces the first contact surface. The apparatus may include an impedance measurement assembly configured to measure impedance of the analysis target using the first electrode and the second electrode. The apparatus may include a processor configured to model the measured impedance as an equivalent circuit, and analyze a biological material component based on a modeling result.Type: GrantFiled: September 8, 2020Date of Patent: July 16, 2024Assignees: SAMSUNG ELECTRONICS CO., LTD., GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kun Sun Eom, Myoung Hoon Jung, Sung Yang, Minkook Son, Alexander Zhbanov, Ye Sung Lee
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Patent number: 12011718Abstract: The present invention relates to a blood diagnostic device, which includes one or more blood input parts into which blood is injected, a deterministic lateral displacement separation part which communicates with the blood input part to form a blood flow path along which the blood flows and separates white blood cells from remaining blood components, a first microchannel which communicates with the deterministic lateral displacement separation part so that the white blood cells separated through the deterministic lateral displacement separation part flow therein, one or more second microchannels which communicate with the deterministic lateral displacement separation part so that the remaining blood components separated through the deterministic lateral displacement separation part flow therein, a first discharge part which communicates with the first microchannel so that the white blood cells flowing in the first microchannel are discharged therethrough, and a second discharge part which communicates with theType: GrantFiled: January 29, 2021Date of Patent: June 18, 2024Assignee: GIST(Gwangju Institute of Science and Technology)Inventors: Sung Yang, Ji Chul Hyun, Yu Gyung Jung
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Patent number: 11773431Abstract: A diagnosis kit is disclosed. The diagnosis kit according to an embodiment of the present invention includes a concentration channel into which a sample containing a methylated DNA is introduced, a concentration chamber connected to the concentration channel, wherein the methylated DNA is concentrated by an ion concentration polarization (ICP) phenomenon and moves to the concentration chamber, a sensing chamber connected to the concentration chamber to allow the methylated DNA inside the concentration chamber to move, allow the methylated DNA moved from inside of the concentration chamber to be hybridized, and allow a methylated DNA binding protein to be bound to the hybridized methylated DNA, and a sensor configured to acquire a first electrochemical signal inside the sensing chamber when the methylated DNA is hybridized and acquire a second electrochemical signal inside the sensing chamber when the methylated DNA binding protein is bound.Type: GrantFiled: July 10, 2018Date of Patent: October 3, 2023Assignee: Gwangju Institute of Science and TechnologyInventors: Sung Yang, Sung A Hong
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Publication number: 20230218209Abstract: An apparatus for analyzing an in vivo component is provided. The apparatus for analyzing an in vivo component may include an impedance sensor including a first electrode and a second electrode configured to contact a fluid channel of a fluid to be analyzed. The apparatus may include an impedance measurement device configured to apply a current to the first electrode and the second electrode, measure a voltage between the first electrode and the second electrode based on applying the current, and measure an impedance of the fluid based on the measured voltage. The apparatus may include a processor configured to model the measured impedance using an equivalent circuit; and analyze the in vivo component based on modeling the measured impedance using the equivalent circuit.Type: ApplicationFiled: March 8, 2023Publication date: July 13, 2023Applicants: SAMSUNG ELECTRONICS CO., LTD., GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Sung YANG, Kun Sun Eom, Myoung Hoon Jung, Byung Jun Kim, Alexander Zhbanov, Seung Yeob Lee, Ye Sung Lee
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Patent number: 11633132Abstract: An apparatus for analyzing an in vivo component is provided. The apparatus for analyzing an in vivo component may include an impedance sensor including a first electrode and a second electrode configured to contact a fluid channel of a fluid to be analyzed. The apparatus may include an impedance measurement device configured to apply a current to the first electrode and the second electrode, measure a voltage between the first electrode and the second electrode based on applying the current, and measure an impedance of the fluid based on the measured voltage. The apparatus may include a processor configured to model the measured impedance using an equivalent circuit; and analyze the in vivo component based on modeling the measured impedance using the equivalent circuit.Type: GrantFiled: January 15, 2020Date of Patent: April 25, 2023Assignees: SAMSUNG ELECTRONICS CO., LTD., GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Sung Yang, Kun Sun Eom, Myoung Hoon Jung, Byung Jun Kim, Alexander Zhbanov, Seung Yeob Lee, Ye Sung Lee
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Publication number: 20220348855Abstract: The present disclosure relates to a herringbone-type fluid guiding unit and an apparatus for concentrating fluid using same. The herring-bone type fluid guiding unit includes: a front member formed on a flow path and formed so that the width between the left side and the right side widens from a front end part toward the back, with respect to the flow direction of a fluid; and a rear member extending from the front member toward the back, wherein the rear member is provided with a recessed part that is recessed to a specific depth from the rear edge toward the front or with a protruding part that protrudes toward the back.Type: ApplicationFiled: July 12, 2022Publication date: November 3, 2022Applicant: GIST(Gwangju Institute of Science and Technology)Inventors: Sung YANG, Ji Chul HYUN
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Patent number: 11384327Abstract: Disclosed herein are methods and devices for antigen-specific T cell identification or neoantigen identification. Also disclosed herein are devices for separating and isolating antigen-specific T cells or other particles of a certain size from a population of particles of different sizes. Also describe herein are methods and devices for the separation and isolation of barcoded T cells from other nanoparticles containing barcodes for subsequent analysis and further processing of a viable T cell.Type: GrantFiled: November 1, 2017Date of Patent: July 12, 2022Assignees: California Institute of Technology, Gwangju Institute of Science and Technology (GIST)Inventors: Songming Peng, James R. Heath, William Chour, Alphonsus Hon-Chung Ng, Sung Yang, Jongchan Choi, Ji-Chul Hyun
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Publication number: 20220170922Abstract: The present invention relates to a multi-microorganism detection system, and more particularly, to a multi-microorganism detection system using a dielectrophoresis force. Provided is a rapid and accurate multi-microorganism detection system. Microorganisms are concentrated at a high throughput using DEP after synthesizing the microorganisms and fluorescent magnetic particles, and when a complex in which the fluorescent magnetic particles are bound to the microorganisms passes through a detection unit by moving only the microorganisms to the detection unit after separating the magnetic particles from the complex (i.e., the microorganisms to which the magnetic particles are bound) using a DEP force, a fluorescence signal of a specific wavelength band is generated according to the type of the fluorescent magnetic particle and the concentration of the microorganisms according to the type of microorganism is measured by measuring and analyzing the fluorescence signal.Type: ApplicationFiled: August 16, 2021Publication date: June 2, 2022Applicant: GIST (Gwangju Institute of Science and Technology)Inventors: Sung YANG, Young Ran YUN, Taek Eon JEONG
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Patent number: 11311876Abstract: An analysis chip for determining an efficient anticancer drug or anticancer drug combination for cancer cells, according to an embodiment of the present disclosure, includes a chamber which is a unit for analyzing single cancer cells, and a plurality of valves configured to regulate a fluid to be injected into the chamber, wherein the chamber includes a channel through which a fluid including an anticancer drug and a cell lysis buffer flows, a cell sorting part configured to focus cancer cells flowing along the channel, a cell capturing part configured to focus the cancer cells focused by the cell storing sorting part, and an antibody array configured to capture proteins secreted from the captured cancer cells and intracellular protein through cell lysis.Type: GrantFiled: July 10, 2018Date of Patent: April 26, 2022Assignee: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Sung Yang, Jong Chan Choi
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Publication number: 20220018807Abstract: The present disclosure relates to a microorganism detection apparatus using a dielectrophoresis (DEP) force.Type: ApplicationFiled: July 20, 2021Publication date: January 20, 2022Applicant: GIST (Gwangju Institute of Science and Technology)Inventors: Sung YANG, Taek Eon JEONG, Jae Hyeon AHN, Yu Gyung JUNG
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Publication number: 20210302345Abstract: An apparatus for analyzing a biological material component may include an impedance sensor comprising a first electrode having a first contact surface that contacts an analysis target, and a second electrode having a second contact surface that contacts the analysis target and that faces the first contact surface. The apparatus may include an impedance measurement assembly configured to measure impedance of the analysis target using the first electrode and the second electrode. The apparatus may include a processor configured to model the measured impedance as an equivalent circuit, and analyze a biological material component based on a modeling result.Type: ApplicationFiled: September 8, 2020Publication date: September 30, 2021Applicants: SAMSUNG ELECTRONICS CO., LTD., GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kun Sun EOM, Myoung Hoon JUNG, Sung YANG, Minkook SON, Alexander ZHBANOV, Ye Sung LEE
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Publication number: 20210146363Abstract: The present invention relates to a blood diagnostic device, which includes one or more blood input parts into which blood is injected, a deterministic lateral displacement separation part which communicates with the blood input part to form a blood flow path along which the blood flows and separates white blood cells from remaining blood components, a first microchannel which communicates with the deterministic lateral displacement separation part so that the white blood cells separated through the deterministic lateral displacement separation part flow therein, one or more second microchannels which communicate with the deterministic lateral displacement separation part so that the remaining blood components separated through the deterministic lateral displacement separation part flow therein, a first discharge part which communicates with the first microchannel so that the white blood cells flowing in the first microchannel are discharged therethrough, and a second discharge part which communicates with theType: ApplicationFiled: January 29, 2021Publication date: May 20, 2021Applicant: GIST(Gwangju Institute of Science and Technology)Inventors: Sung YANG, Ji Chul HYUN, Yu Gyung JUNG
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Publication number: 20210139961Abstract: A diagnosis kit is disclosed. The diagnosis kit according to an embodiment of the present invention includes a concentration channel into which a sample containing a methylated DNA is introduced, a concentration chamber connected to the concentration channel, wherein the methylated DNA is concentrated by an ion concentration polarization (ICP) phenomenon and moves to the concentration chamber, a sensing chamber connected to the concentration chamber to allow the methylated DNA inside the concentration chamber to move, allow the methylated DNA moved from inside of the concentration chamber to be hybridized, and allow a methylated DNA binding protein to be bound to the hybridized methylated DNA, and a sensor configured to acquire a first electrochemical signal inside the sensing chamber when the methylated DNA is hybridized and acquire a second electrochemical signal inside the sensing chamber when the methylated DNA binding protein is bound.Type: ApplicationFiled: July 10, 2018Publication date: May 13, 2021Inventors: Sung YANG, Sung A HONG
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Publication number: 20210078000Abstract: An analysis chip for determining an efficient anticancer drug or anticancer drug combination for cancer cells, according to an embodiment of the present disclosure, includes a chamber which is a unit for analyzing single cancer cells, and a plurality of valves configured to regulate a fluid to be injected into the chamber, wherein the chamber includes a channel through which a fluid including an anticancer drug and a cell lysis buffer flows, a cell sorting part configured to focus cancer cells flowing along the channel, a cell capturing part configured to focus the cancer cells focused by the cell storing part, and an antibody array configured to capture proteins secreted from the captured cancer cells and intracellular protein through cell lysis.Type: ApplicationFiled: July 10, 2018Publication date: March 18, 2021Inventors: Sung YANG, Jong Chan CHOI