Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.

Abstract: A hands-free kit for cellular phones containing earpiece set installed inside a newly designed carrying case. The earpiece set of this invention is installed inside the cellular phone carrying case of this invention. The earpiece set consists of, including but not limited to, a microphone, an earpiece, electric wire and a mechanical spring winder. The hands-free kit of this invention consists of, including but not limited to, a plastic carrying case, an adaptor, and an earpiece set connected to an on/off switch via thin copper wires coated with flexible plastic. The earpiece set of this invention is coiled inside the cellular phone carrying case of this invention by a mechanical spring winder installed inside the case. One end of the earpiece set is connected to the on/off switch, which is connected with the cellular phone main body via the earphone jack. The other end of the earpiece set is exposed out of the spring winder.