Abstract: The present invention relates to: a substituted thiazolidinedione derivative compound having a novel structure acting as a sterol regulatory element-binding protein-1 (SREBP1) inhibitor, a hydrate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating cancer, comprising same as an active ingredient.

Abstract: Disclosed is a small lens system including a first lens, a second lens, a third lens, and a fourth lens sequentially arranged from an object along an optical axis, wherein the thickness (ct1) of the first lens, the thickness (ct3) of the second lens, the thickness (ct5) of the third lens, and the thickness (ct7) of the fourth lens satisfy ct1+ct3>ct5+ct7, ct1>ct3, ct1>ct5, and ct1>ct7, the front surface of the first lens is convex toward the object while the sagittal amount of the first lens is increased depending on the height thereof, the refractive power (P2) of the second lens satisfies ?0.01 mm?1<P2<0.01 mm?1, the front curvature (C3) and the rear curvature (C4) of the second lens satisfy |C3|<0.1 mm?1 and |C4|<0.1 mm?1, and the f-number of the lens system is less than 1.4.

Abstract: A support unit may include a plurality of heaters disposed in a matrix form in the support unit to heat a substrate, and a power supply unit for supplying power to the plurality of heaters, wherein a current applied to the plurality of heaters is controlled by switches connected to rows and columns of the matrix, respectively, and the switches connected to the rows of the matrix include first switches capable of controlling the current applied to the rows of the matrix and second switches connected in parallel with the first switches.

Abstract: Proposed is a prefilled patch including an adhesive layer configured to be attached to the skin, a capsule which is provided on the adhesive layer and in which an active ingredient or a drug is stored, and a handle connected to a discharge hole formed in the capsule, wherein the handle is separated from the capsule by a user to open the discharge hole.

Abstract: A high-density microneedle of the present disclosure includes: a sheet portion attached to skin; a substrate portion arranged on the sheet portion; and a plurality of insertion pieces arranged on the substrate portion, wherein the substrate portion is arranged on the sheet portion while having a plurality of layers formed therein.

Abstract: A floating foundation includes a plurality of unit modules that can be fabricated in an efficient manner and then assembled, on shore or afloat near the deployment location. The floating foundation can be applied to various offshore energy systems, such as wind power generation, and in deployment locations with limited infrastructure.

Abstract: Provided is a floating foundation for supporting a wind power generation system including a stabilized power cable. In one embodiment, the floating foundation includes a column extending upwardly and couplable at a top end thereof to a base of the wind turbine, at least one power cable for exporting power generated from the wind turbine to another floating foundation or to an offshore/onshore station, and a plurality of buoyancy modules disposed along the at least one power cable. Power cables between a plurality of floating foundations and/or power station may be supported by buoyant modules such that the power cable is located in an optimal submergence range of the water body in which the floating foundations are deployed.

Abstract: The present disclosure provides the compound having inhibitory property against TNIK having a specific chemical structure or its pharmaceutically acceptable salt. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating or preventing cancer. The present disclosure also provides a method of treatment or prevention of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment or prevention.

Abstract: A floating foundation includes a plurality of unit modules that can be fabricated in an efficient manner and then assembled, on shore or afloat near the deployment location. The floating foundation can be applied to various offshore energy systems, such as wind power generation, and in deployment locations with limited infrastructure.

Abstract: Proposed is a patch for the alleviation and prevention of acne, in which anti-acne activity of a biodegradable metal represented by MgaZnbXc (in which a, b and c are wt % of individual components, a+b+c=100 wt %, 0?a?100, 0?b?100, and 0?c?10, among which a or b is the greatest, and X is at least one selected from the group consisting of Ca, Fe, Mn, Si, Na, Zr, Ce, and P) is demonstrated, thus exhibiting novel use thereof as a patch for the alleviation and prevention of acne.

Abstract: The present disclosure provides the compound having inhibitory property against TNIK having a specific chemical structure or its pharmaceutically acceptable salt. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating or preventing cancer. The present disclosure also provides a method of treatment or prevention of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment or prevention.

Abstract: Disclosed is an air pressure control (APC) device according to an embodiment of the inventive concept. The air pressure control (APC) device may include a processing chamber, a plate for adjusting a pressure in the processing chamber, and an APC valve including first and second step motors for adjusting a height of the plate, and an APC controller that controls the APC valve, and the APC controller may include a first controller that controls positions of the first step motor and the second step motor; and a second controller that compensates for a difference in position between the first step motor and the second step motor.

Abstract: The present disclosure provides the compound having inhibitory property against TNIK having a specific chemical structure or its pharmaceutically acceptable salt. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating or preventing cancer. The present disclosure also provides a method of treatment or prevention of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment or prevention.

Abstract: A tissue removal device includes a housing, a catheter extending from the housing and configured to be inserted into the body of a patient, a bending unit including a plurality of bending blocks that is disposed at a front end portion of the catheter and at least one or more wires that control a motion direction of the bending blocks, and a tissue removal unit disposed at the front end portion of the catheter and configured to come in contact with a tissue to be removed.

Abstract: The present disclosure provides the compound having inhibitory property against TNIK having a specific chemical structure or its pharmaceutically acceptable salt. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating or preventing cancer. The present disclosure also provides a method of treatment or prevention of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment or prevention.

Abstract: A platform for a semi-submersible floating type offshore structure according to an exemplary embodiment of the present invention includes a main body which is installed on the sea and has an arrangement structure in which a plurality of pontoons is combined to form a plurality of polygonal shapes; and a protrusion member connecting unit which extends from each corner of the main body and connects a protrusion member outwardly protruding from the main body to the main body.

Abstract: The present invention relates to a fixing piece firing device for a dental membrane, the device being capable of firing the fixing piece to fix the dental membrane that covers a graft site after bone graft during implant surgery, and of facilitating access into an oral cavity due to a tip part with a curved front end, thus enabling a quick and easy procedure without using a typical dental drill.

Abstract: Provided is a gap measuring method capable of accurately measuring a gap between adjacent members.

Abstract: The present invention relates to a flexible metal patch having antioxidant activity and brightening activity, the patch containing a biodegradable metal represented by Chemical Formula 1. The patch has DPPH free radical scavenge activity, thereby being useful in implementing antioxidant and brightening functions. Since the patch itself exhibits antioxidant activity and brightening activity without requiring combined use with other natural extracts or synthetic compounds, the patch can be easily used, can be easily locally applied to a region around or under the eyes. The patch is useful in preparation of cosmetics having effective antioxidant activity and brightening activity. Chemical Formula 1 MgaXb where a and b are in units of % by weight, a+b=100% by weight, 5<a<100, and X is any one or a combination of two or more selected from the group consisting of Zn, Ca, Fe, Mn, Si, Na, Zr, Ce, Ag, and P.

Abstract: A support unit may include a plurality of heaters disposed in a matrix form in the support unit to heat a substrate, and a power supply unit for supplying power to the plurality of heaters, wherein a current applied to the plurality of heaters is controlled by switches connected to rows and columns of the matrix, respectively, and the switches connected to the rows of the matrix include first switches capable of controlling the current applied to the rows of the matrix and second switches connected in parallel with the first switches.