Abstract: A NOx storage catalyst includes CHA zeolite, a transition metal ion-exchanged in the CHA zeolite, and a rare earth metal that is different the transition metal and is supported on the CHA zeolite. A method for preparing a NOx storage catalyst includes preparing a synthetic mother liquid including a zeolite raw material as a source of silica and alumina, a structure-inducing material, a complexing material, and a solvent, reacting the synthetic mother liquid to prepare a CHA zeolite, and supporting a transition metal and a rare earth metal that is different from the transition metal on the prepared CHA zeolite.

Abstract: In an air conditioner, a drain extraction unit and a refrigerant pipe connecting unit may be disposed in a blocking region in which a discharge port is not provided so that a size of the discharge port may be secured and the discharge port may be uniformly disposed, thereby generating uniform airflow in a room. In a lower housing formed in a circular shape, some of components inside an indoor unit of the air conditioner may be disposed in a protrusion portion that protrudes from the circular housing, thereby facilitating the installation of the air conditioner. A condensate water collecting space disposed outside the housing may be provided in a drain tray, thereby efficiently preventing a leakage due to condensate water generated outside the housing. The housing, the drain tray, and the cover member of the air conditioner may be coupled by a coupling member coupled outside.

Abstract: A high-density microneedle of the present disclosure includes: a sheet portion attached to skin; a substrate portion arranged on the sheet portion; and a plurality of insertion pieces arranged on the substrate portion, wherein the substrate portion is arranged on the sheet portion while having a plurality of layers formed therein.

Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

Abstract: In an air conditioner, a drain extraction unit and a refrigerant pipe connecting unit may be disposed in a blocking region in which a discharge port is not provided so that a size of the discharge port may be secured and the discharge port may be uniformly disposed, thereby generating uniform airflow in a room. In a lower housing formed in a circular shape, some of components inside an indoor unit of the air conditioner may be disposed in a protrusion portion that protrudes from the circular housing, thereby facilitating the installation of the air conditioner. A condensate water collecting space disposed outside the housing may be provided in a drain tray, thereby efficiently preventing a leakage due to condensate water generated outside the housing. The housing, the drain tray, and the cover member of the air conditioner may be coupled by a coupling member coupled outside.

Abstract: Proposed is a patch for the alleviation and prevention of acne, in which anti-acne activity of a biodegradable metal represented by MgaZnbXc (in which a, b and c are wt % of individual components, a+b+c=100 wt %, 0?a?100, 0?b?100, and 0?c?10, among which a or b is the greatest, and X is at least one selected from the group consisting of Ca, Fe, Mn, Si, Na, Zr, Ce, and P) is demonstrated, thus exhibiting novel use thereof as a patch for the alleviation and prevention of acne.

Abstract: A tissue removal device includes a housing, a catheter extending from the housing and configured to be inserted into the body of a patient, a bending unit including a plurality of bending blocks that is disposed at a front end portion of the catheter and at least one or more wires that control a motion direction of the bending blocks, and a tissue removal unit disposed at the front end portion of the catheter and configured to come in contact with a tissue to be removed.

Abstract: The present invention relates to a flexible metal patch having antioxidant activity and brightening activity, the patch containing a biodegradable metal represented by Chemical Formula 1. The patch has DPPH free radical scavenge activity, thereby being useful in implementing antioxidant and brightening functions. Since the patch itself exhibits antioxidant activity and brightening activity without requiring combined use with other natural extracts or synthetic compounds, the patch can be easily used, can be easily locally applied to a region around or under the eyes. The patch is useful in preparation of cosmetics having effective antioxidant activity and brightening activity. Chemical Formula 1 MgaXb where a and b are in units of % by weight, a+b=100% by weight, 5<a<100, and X is any one or a combination of two or more selected from the group consisting of Zn, Ca, Fe, Mn, Si, Na, Zr, Ce, Ag, and P.

Abstract: The present invention relates to a thread embedding therapy rope and a thread embedding therapy needle apparatus comprising same, and disclosed are a thread embedding therapy rope and a needle apparatus comprising same, the rope comprising a linear core, which comprises a biodegradable polymer, and a metal wire, which is arranged to spirally encompass the outer circumferential surface of the linear core, wherein the metal wire comprises a biodegradable metal formed with magnesium or zinc as a main component, so as to have no side effects on biological tissue when applied to the human body by means of thread embedding therapy, pulling force on the tissue can be strengthened, lifespan can be extended over that of a conventional embedded thread of a biodegradable polymer, the drug loading capability of the embedded thread itself can be increased so as to allow for usefulness as a drug carrier, and a drug can be delivered through a simple method.

Abstract: A microneedle using a biodegradable metal is represented by Chemical Formula 1 and is absorbed and degraded after subcutaneous or epithelial insertion to thus release metal ions and degradation products into the body. In Chemical Formula 1, a, b, and c represent wt % of respective ingredients, a+b+c=100 wt %, a or b has the highest value in the range of 0?a?100, 0?b?100, and 0?c?10, and X is one or more selected from the group consisting of Ca, Fe, Mn, Si, Na, Zr, Ce, and P.

Abstract: Proposed is a patch for the alleviation and prevention of acne, in which anti-acne activity of a biodegradable metal represented by MgaZnbXc (in which a, b and c are wt % of individual components, a+b+c=100 wt %, 0?a?100, 0?b?100, and 0?c?10, among which a or b is the greatest, and X is at least one selected from the group consisting of Ca, Fe, Mn, Si, Na, Zr, Ce, and P) is demonstrated, thus exhibiting novel use thereof as a patch for the alleviation and prevention of acne.

Abstract: A multi-type microneedle is proposed. The multi-type microneedle includes: a substrate part; a plurality of needle holes provided in the substrate part; a plurality of needle parts provided at a predetermined distance from each other along a circumferential direction of each of the needle holes on an area of the substrate part partitioning each of the needle holes; and a patch in contact with a user's skin while in contact with one surface of the substrate part, wherein since the needle parts is provided in a certain pattern around one needle hole by further having a drug injection part or a drug storage part capable of additionally supplying a drug, the needle parts are inserted into a predetermined area of the skin so that the drug to be delivered into the body may be rapidly diffused or permeated subcutaneously, and also an amount of the drug delivered is controlled.

Abstract: A high-density microneedle of the present disclosure includes: a sheet portion attached to skin; a substrate portion arranged on the sheet portion; and a plurality of insertion pieces arranged on the substrate portion, wherein the substrate portion is arranged on the sheet portion while having a plurality of layers formed therein.

Abstract: Disclosed is a microneedle array. The microneedle array includes a substrate, a plurality of needle openings provided in the substrate, and a plurality of needle units disposed around respective needle openings and each having a plurality of microneedles circumferentially arranged at regular intervals around respective needle opening to protrude from the substrate so as to be inserted into the skin.

Abstract: The present invention includes: a substrate portion; a needle portion provided at the substrate portion and protruding from the substrate portion to be inserted into skin; and a perforated portion provided at a junction between the needle portion and the substrate portion, wherein either of the substrate portion and the needle portion is made of the bioabsorbable metal.

Abstract: A microneedle using a biodegradable metal is represented by Chemical Formula 1 and is absorbed and degraded after subcutaneous or epithelial insertion to thus release metal ions and degradation products into the body. In Chemical Formula 1, a, b, and c represent wt % of respective ingredients, a+b+c=100 wt %, a or b has the highest value in the range of 0?a?100, 0?b?100, and 0?c?10, and X is one or more selected from the group consisting of Ca, Fe, Mn, Si, Na, Zr, Ce, and P.

Abstract: This invention relates to a biodegradable implant including magnesium, wherein the magnesium contains, as impurities, (i) manganese (Mn); and (ii) one selected from the group consisting of iron (Fe), nickel (Ni) and mixtures of iron (Fe) and nickel (Ni), wherein the impurities satisfy the following condition: 0<(ii)/(i)?5, and an amount of the impurities is 1 part by weight or less but exceeding 0 parts by weight based on 100 parts by weight of the magnesium, and to a method of manufacturing the same.

Abstract: The present invention relates to a magnesium alloy having controlled corrosion resistance properties, which comprises magnesium (Mg) and an alloying element and includes a magnesium phase and a phase composed of magnesium and the alloying element, wherein the difference in electrical potential between the magnesium phase and the phase composed of magnesium and the alloying element is greater than 0 V but not greater than 0.2 V.

Abstract: This invention relates to a biodegradable implant including magnesium, wherein the magnesium contains, as impurities, (i) manganese (Mn); and (ii) one selected from the group consisting of iron (Fe), nickel (Ni) and mixtures of iron (Fe) and nickel (Ni), wherein the impurities satisfy the following condition: 0<(ii)/(i)?5, and an amount of the impurities is 1 part by weight or less but exceeding 0 parts by weight based on 100 parts by weight of the magnesium, and to a method of manufacturing the same.

Abstract: The present invention relates to a magnesium alloy having controlled corrosion resistance properties, which comprises magnesium (Mg) and an alloying element and includes a magnesium phase and a phase composed of magnesium and the alloying element, wherein the difference in electrical potential between the magnesium phase and the phase composed of magnesium and the alloying element is greater than 0 V but not greater than 0.2 V.