Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.

Abstract: The disclosure relates to a semiconductor memory device including a semiconductor memory module and a semiconductor memory control unit, and since the semiconductor memory module includes a power management unit, and the power management unit generates a reference voltage and various internal voltages to be supplied to a dynamic random access memory (DRAM) chip array, and receives the internal voltages supplied to the DRAM chip array by feedback to measure and compensate the internal voltages, a stable and accurate voltage can be supplied to the DRAM chip array.