Abstract: Provided are stretchable electronics and a method for manufacturing the same. The stretchable electronics may include a substrate, a plurality of electronic elements disposed to be spaced apart from each other on the substrate, and a wire structure disposed on the substrate to connect the plurality of electronic elements to each other. The wire structure may include an insulator extending from one of the electronic elements to the other of the adjacent electronic elements and a metal wire configured to cover a top surface and side surfaces of the insulator. The insulator may include at least one bent part in a plan view.

Abstract: A collision accident response system for a vehicle includes: a transparent glass attached to a front surface of the vehicle; a transparent pressure sensor film attached to a rear surface of the transparent glass; and a control unit embedded in the vehicle. The control unit is configured to determine a height and a collision strength of a collision object by a collision pressure detected by the transparent pressure sensor film. As a result, the collision accident response system for a vehicle enables a rapid and accurate response to collision accidents in vehicles equipped with the front glass.

Abstract: An artificial intelligence (AI) system capable of simulating functions of a human brain, such as recognition and judgment, by using the machine learning algorithm such as deep learning, and an application thereof are provided. A method of learning multi-modal data according to the AI system and an application thereof includes: obtaining first context information representing a characteristic of a first signal and second context information representing a characteristic of a second signal by using a first learning network model; obtaining hidden layer information based on the first context information and the second context information by using a second learning network model; obtaining a correlation value representing a relation degree between the hidden layer information by using the second learning network model; and learning the hidden layer information in which the correlation value is derived as a maximum value.

Abstract: The present invention relates to an orally-administered gene carrier and a use thereof, and more specifically, to: an oral gene carrier comprising, at the C-terminus of an immunoglobulin Fc region, a linker formed from cationic arginine and enabling the condensation of an anionic gene; and an oral composition for preventing, ameliorating or treating metabolic diseases, the composition comprising the gene carrier and the GLP-1 gene as active ingredients. The gene carrier, according to the present invention, may be usefully employed as an orally-administered carrier for various genes, and especially, is expected to be usable for preventing, ameliorating or treating metabolic diseases, such as diabetes and obesity, by effectively transferring the GLP-1 gene.

Abstract: The present invention relates to a nanoparticle for oral gene delivery, which is a novel oral gene delivery system capable of regulating blood glucose levels in biological systems and insulin secretion in response to ingested meals. More specifically, the present invention relates to a nanoparticle for gene delivery, comprising: an ionic polymer conjugated with bile acid or a bile acid derivative; and a gene; and to a pharmaceutical composition comprising the same.

Abstract: The present invention relates to an orally-administered gene carrier, and more specifically, to an orally-administered gene carrier having cationic protamine connected to an immunoglobulin Fc region by an SMCC linker, the cationic protamine enabling the condensation of an anionic gene. The orally-administered gene carrier enables protamine, which is a protein having cationic properties, to bind to an Fc region and be condensed with a gene having anionic properties, and thus may effectively induce the in vivo expression of the gene, and when orally administered, may enable the gene to be transferred to the small intestine by protecting the gene from a degradation reaction resulting from an immune action of white blood cells and stomach acid, and may enable the half-life of the gene to be relatively long when the gene is expressed in the small intestine, and thus a potential for a long-term treatment effect has been confirmed.

Abstract: An artificial intelligence (AI) system capable of simulating functions of a human brain, such as recognition and judgment, by using the machine learning algorithm such as deep learning, and an application thereof are provided. A method of learning multi-modal data according to the AI system and an application thereof includes: obtaining first context information representing a characteristic of a first signal and second context information representing a characteristic of a second signal by using a first learning network model; obtaining hidden layer information based on the first context information and the second context information by using a second learning network model; obtaining a correlation value representing a relation degree between the hidden layer information by using the second learning network model; and learning the hidden layer information in which the correlation value is derived as a maximum value.

Abstract: The present invention relates to an orally-administered gene carrier and a use thereof, and more specifically, to: an oral gene carrier comprising, at the C-terminus of an immunoglobulin Fc region, a linker formed from cationic arginine and enabling the condensation of an anionic gene; and an oral composition for preventing, ameliorating or treating metabolic diseases, the composition comprising the gene carrier and the GLP-1 gene as active ingredients. The gene carrier, according to the present invention, may be usefully employed as an orally-administered carrier for various genes, and especially, is expected to be usable for preventing, ameliorating or treating metabolic diseases, such as diabetes and obesity, by effectively transferring the GLP-1 gene.

Abstract: The present invention relates to a nanoparticle for oral gene delivery, which is a novel oral gene delivery system capable of regulating blood glucose levels in biological systems and insulin secretion in response to ingested meals. More specifically, the present invention relates to a nanoparticle for gene delivery, comprising: an ionic polymer conjugated with bile acid or a bile acid derivative; and a gene; and to a pharmaceutical composition comprising the same.