Abstract: An operation method of an application system includes receiving a chat room-entry event notifying that a user enters the chat room from a terminal in which an application is installed, generating an entry trigger based on the chat room enter event, and providing user context suitable information inferred based on a user key included in the entry trigger to the chat room.

Abstract: A method for evaluating appropriateness of dosage of a target drug administered to a patient is adapted to be implemented by a computing device that stores a dosage evaluation model. The method comprises steps of: obtaining at least one physiological parameter that is related to a physiological condition of the patient; obtaining at least one medication parameter that is related to a usage condition of the target drug by the patient; and feeding said at least one physiological parameter and said at least one medication parameter into the dosage evaluation model to obtain an evaluation result that indicates the appropriateness of the dosage of the target drug administered to the patient.

Abstract: In an apparatus for manufacturing a micro-channel and a method for manufacturing a micro-channel, the apparatus includes a base member and a holding chamber. The base member includes a first base member having a concave portion and a convex portion, and a second base member covering the concave portion to form a channel. The holding chamber holds the base member thereinside, to form a space uniformly applying a pressure on a surface of the base member. Accordingly, the pressure is uniformly applied on an entire surface of the base member and thus the micro-channel may be manufactured.

Abstract: The present invention relates to a method of preparing vascular endothelial cells by transforming (transdifferentiating) adult fibroblasts and a composition, which includes vascular endothelial cells prepared according to the method, for preventing and treating ischemic diseases, the method including a step of transducing adult fibroblasts with a gene. In particular, the present invention confirms that five factors, Foxo1, Er71, Klf2, Tal1, and Lmo2, induce transdifferentiation of adult fibroblasts into induced vascular endothelial cells. Furthermore, the present invention confirms that three factors, Er71, Klf2, and Tal1 induce transdifferentiation of human adult fibroblasts into induced vascular endothelial cells. The resultant induced endothelial cells enable lower limb salvaging by angiogenesis in lower limb ischemic animal models, showing that the induced endothelial cells can be effectively used for prevention or treatment of ischemic diseases.

Abstract: Provided is a technique for transmitting and receiving a chat message through a message server. A user transmits and receives a chat message to and from a friend of a first type and receives a chat message from a friend of a second type, and receives various chat messages from a company supporting the friend of the second type.

Abstract: Provided is a technique for transmitting and receiving a chat message through a message server. A user transmits and receives a chat message to and from a friend of a first type and receives a chat message from a friend of a second type, and receives various chat messages from a company supporting the friend of the second type.

Abstract: Provided is a technique for transmitting and receiving a chat message through a message server. A user may transmit and receive a chat message to and from a friend of a first type and may receive a chat message from a friend of a second type, and receive various chat messages from a company supporting the friend of the second type.

Abstract: The present invention relates to a method of preparing vascular endothelial cells by transforming (transdifferentiating) adult fibroblasts and a composition, which includes vascular endothelial cells prepared according to the method, for preventing and treating ischemic diseases, the method including a step of transducing adult fibroblasts with a gene. In particular, the present invention confirms that five factors, Foxo1, Er71, Klf2, Tal1, and Lmo2, induce transdifferentiation of adult fibroblasts into induced vascular endothelial cells. Furthermore, the present invention confirms that three factors, Er71, Klf2, and Tal1 induce transdifferentiation of human adult fibroblasts into induced vascular endothelial cells. The resultant induced endothelial cells enable lower limb salvaging by angiogenesis in lower limb ischemic animal models, showing that the induced endothelial cells can be effectively used for prevention or treatment of ischemic diseases.

Abstract: In an apparatus for manufacturing a micro-channel and a method for manufacturing a micro-channel, the apparatus includes a base member and a holding chamber. The base member includes a first base member having a concave portion and a convex portion, and a second base member covering the concave portion to form a channel. The holding chamber holds the base member thereinside, to form a space uniformly applying a pressure on a surface of the base member. Accordingly, the pressure is uniformly applied on an entire surface of the base member and thus the micro-channel may be manufactured.

Abstract: A method of manufacturing a roll for roll printing/roll imprinting is provided. The method includes preparing an exterior on one surface of which a printed pattern of a predetermined shape is formed and that has magnetic power and having the other surface of the exterior contact an external surface of a central roll so that the exterior is attached to the central roll having magnetic power by magnetic power. Therefore, the method of manufacturing a roll for roll printing/roll imprinting capable of reducing production cost to massively manufacture the roll for roll printing/roll imprinting is provided.

Abstract: Disclosed is an apparatus for self-extracting a cell using a magnetic field. The apparatus for self-extracting the cell using the magnetic field according to the present invention includes a flow path casing including an upper substrate and a lower substrate having a magnetic property combined with each other, and a fluid path formed to fluidize a cell solution therein; a separation portion disposed on the fluid path and provided with a separation channel selectively passing only an effective cell that is a separation target in the cell included in the cell solution therethrough; and a magnetic field control portion forming the magnetic field in the flow path portion to separate the cell blocking the separation channel from the separation channel.

Abstract: An apparatus for separating cells using magnetic force includes: a separation channel portion including ferromagnetic particles, and provided with a flow path through which a cell fluid containing a plurality of cells having at least one of diamagnetic and paramagnetic properties; and a magnetic field controller that generates a magnetic field within the flow path so that the cells in the cell fluid flow within the flow path and are separated by height by a magnetic field. Accordingly, there are provided an apparatus for separating cells using magnetic force and a cell separation method using the same, by which cells can be easily separated using magnetic force.

Abstract: Provided is a technique for transmitting and receiving a chat message through a message server. A user may transmit and receive a chat message to and from a friend of a first type and may receive a chat message from a friend of a second type, and receive various chat messages from a company supporting the friend of the second type.

Abstract: Disclosed is an apparatus for self-extracting a cell using a magnetic field. The apparatus for self-extracting the cell using the magnetic field according to the present invention includes a flow path casing including an upper substrate and a lower substrate having a magnetic property combined with each other, and a fluid path formed to fluidize a cell solution therein; a separation portion disposed on the fluid path and provided with a separation channel selectively passing only an effective cell that is a separation target in the cell included in the cell solution therethrough; and a magnetic field control portion forming the magnetic field in the flow path portion to separate the cell blocking the separation channel from the separation channel.

Abstract: An apparatus for separating cells using magnetic force includes: a separation channel portion including ferromagnetic particles, and provided with a flow path through which a cell fluid containing a plurality of cells having at least one of diamagnetic and paramagnetic properties; and a magnetic field controller that generates a magnetic field within the flow path so that the cells in the cell fluid flow within the flow path and are separated by height by a magnetic field. Accordingly, there are provided an apparatus for separating cells using magnetic force and a cell separation method using the same, by which cells can be easily separated using magnetic force.

Abstract: A method of manufacturing a roll for roll printing/roll imprinting is provided. The method includes preparing an exterior on one surface of which a printed pattern of a predetermined shape is formed and that has magnetic power and having the other surface of the exterior contact an external surface of a central roll so that the exterior is attached to the central roll having magnetic power by magnetic power. Therefore, the method of manufacturing a roll for roll printing/roll imprinting capable of reducing production cost to massively manufacture the roll for roll printing/roll imprinting is provided.

Abstract: A lithography apparatus is provided. The lithography apparatus includes: a polarizing filter that converts incident light to first polarized light having a single polarizing direction; and a photo mask that is disposed to be separated from the polarizing filter and in which a polarizing pattern having a polarization axis of a predetermined direction in order to convert the applied first polarized light to second polarized light by adjusting a transmittance of the first polarized light and a light blocking pattern that blocks the first polarized light are formed, wherein by radiating light in which a transmittance is adjusted in the photo mask, the photoresist is patterned.