Publication number: 20250066347
Abstract: The present invention relates to: a substituted thiazolidinedione derivative compound having a novel structure acting as a sterol regulatory element-binding protein-1 (SREBP1) inhibitor, a hydrate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating cancer, comprising same as an active ingredient.
Type:
Application
Filed:
December 19, 2022
Publication date:
February 27, 2025
Inventors:
Jun-Kyum KIM, Jia CHOI, Eun-Jung KIM, Cheol-Kyu PARK, Seok Won HAM, Min Gi PARK, Hyeon Ju JEONG, Sung Jin KIM, Kyungim MIN, Jong Min PARK, Jungwook CHIN, Sung Jin CHO, Jina KIM, Kyung Jin JUNG, Nayeon KIM, Suhui KIM, Sugyeong KWON, Su-Jeong LEE, Minseon JEONG, Hongchan AN, Jeong-Eun PARK, Dong-Hyun KIM, Ji-youn LIM, Ju-sik MIN, Ji Sun HWANG, Hyo-Jung CHOI, Hayoung HWANG, Oh-Bin KWON, Sungwoo LEE, Sang Bum KIM
Publication number: 20230365530
Abstract: A compound, a stereoisomer thereof, a hydrate thereof, or a pharmaceutically acceptable salt thereof, provided as one aspect of the present invention, exhibits a high inhibitory ability on euchromatic histone-lysine N-methyltransferase 2 (EHMT2), and thus, the compound can be usefully used for the treatment of cancer.
Type:
Application
Filed:
September 16, 2021
Publication date:
November 16, 2023
Inventors:
Jung Jin HWANG, Sang Eun PARK, Dong Eun KIM, Ji-Ye HONG, Choung-Soo KIM, Woo Chan SON, Shinae KIM, Sugyeong KWON, Kyungjin JUNG, Nayeon KIM, Jina KIM, Kyung-Hee KIM, Jung Wook CHIN, Sung Jin CHO, Sehan LEE, Eunju CHA, Jeongmin JOO, Ji Sun HWANG, Jeong-Eun PARK, Ji Hoon YU, Eunmi HONG, Young-Hoon PARK, Ju-Hee LEE