Patents by Inventor Sungwhan Oh

Sungwhan Oh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYCOLIPID COMPOSITIONS AND METHODS OF USE
    Publication number: 20230130767
    Abstract: The invention provides immunostimulatory glycolipids and compositions thereof and methods of use thereof.
    Type: Application
    Filed: October 13, 2022
    Publication date: April 27, 2023
    Applicant: President and Fellows of Harvard College
    Inventors: Sungwhan Oh, Deniz Erturk-Hasdemir, Dennis L. Kasper, Kailyn L. Stefan
  • Glycolipid compositions and methods of use
    Patent number: 11491181
    Abstract: The invention provides immunostimulatory glycolipids and compositions thereof and methods of use thereof.
    Type: Grant
    Filed: July 15, 2017
    Date of Patent: November 8, 2022
    Assignee: President and Fellows of Harvard College
    Inventors: Sungwhan Oh, Deniz Erturk-Hasdemir, Dennis L. Kasper, Kailyn L. Stefan
  • IMMUNOMODULATORY GLYCOSPHINGOLIPIDS AND METHODS OF USE THEREOF
    Publication number: 20220125838
    Abstract: Provided herein are a subset of alpha-galactosylceramide (alpha-GC) compounds having improved immunomodulatory activity, particularly with respect to NKT cell number and activity. Also provided herein are methods of use of such compounds, including in the modulation of NKT cells and/or activity in vivo. Further provided are combinatorial synthesis methods for generating alpha-GC compounds of specifically defined structure and thereby generating pure preparations thereof.
    Type: Application
    Filed: January 15, 2020
    Publication date: April 28, 2022
    Applicants: President and Fellows of Harvard College, Seoul National University R&DB Foundation
    Inventors: Sungwhan Oh, Dennis L. Kasper, Heebum Song, Seung Bum Park
  • LIPIDATED PSA COMPOSITIONS AND METHODS
    Publication number: 20210315923
    Abstract: The invention provides various isolated and synthetic forms of lipidated PSA as well as isolated or synthetic forms of the glycolipid component of lipidated PSA, and compositions thereof, methods of making including methods of isolating such forms, and methods of use thereof.
    Type: Application
    Filed: November 3, 2020
    Publication date: October 14, 2021
    Applicant: President and Fellows of Harvard College
    Inventors: Sungwhan Oh, Deniz Erturk-Hasdemir, Dennis L. Kasper
  • Lipidated PSA compositions and methods
    Patent number: 10857177
    Abstract: The invention provides various isolated and synthetic forms of lipidated PSA as well as isolated or synthetic forms of the glycolipid component of lipidated PSA, and compositions thereof, methods of making including methods of isolating such forms, and methods of use thereof.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: December 8, 2020
    Assignee: President and Fellows of Harvard College
    Inventors: Sungwhan Oh, Deniz Erturk-Hasdemir, Dennis L. Kasper
  • GLYCOLIPID COMPOSITIONS AND METHODS OF USE
    Publication number: 20190290680
    Abstract: The invention provides immunostimulatory glycolipids and compositions thereof and methods of use thereof.
    Type: Application
    Filed: July 15, 2017
    Publication date: September 26, 2019
    Applicant: President and Fellows of Harvard College
    Inventors: Sungwhan Oh, Deniz Erturk-Hasdemir, Dennis L. Kasper
  • Glycosphingolipids and methods of use thereof
    Patent number: 10329315
    Abstract: The invention provides, inter alia, immunoinhibitory glycosphingolipids and immunoinhibitory alpha-galactosylceramides and compositions and preparations thereof, and methods of use thereof including in the treatment of conditions characterized by increased iNKT cells and/or activity.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: June 25, 2019
    Assignees: The Brigham and Women's Hospital, Inc., President and Fellows of Harvard College
    Inventors: Dennis L. Kasper, Dingding An, Sungwhan Oh, Richard S. Blumberg, Torsten Olszak, Joana F. Neves
  • LIPIDATED PSA COMPOSITIONS AND METHODS
    Publication number: 20190046560
    Abstract: The invention provides various isolated and synthetic forms of lipidated PSA as well as isolated or synthetic forms of the glycolipid component of lipidated PSA, and compositions thereof, methods of making including methods of isolating such forms, and methods of use thereof.
    Type: Application
    Filed: August 19, 2016
    Publication date: February 14, 2019
    Applicant: President and Fellows of Harvard College
    Inventors: Sungwhan Oh, Deniz Erturk-Hasdemir, Dennis L. Kasper
  • GLYCOSPHINGOLIPIDS AND METHODS OF USE THEREOF
    Publication number: 20150252068
    Abstract: The invention provides, inter alia, immunoinhibitory glycosphingolipids and immunoinhibitory alpha-galactosylceamides and compositions and preparations thereof, and methods of use thereof including in the treatment of conditions characterized by increased iNKT cells and/or activity.
    Type: Application
    Filed: October 11, 2013
    Publication date: September 10, 2015
    Inventors: Dennis L. Kasper, Dingding An, Sungwhan Oh, Richard S. Blumberg, Torsten Olszak, Joana Pereira Das Neves