Abstract: The present invention relates to the development of a dural substitute biomaterial using human dura-derived stem cells and to a dural substitute prepared therefrom. Specifically, dural substitutes in the form of nanofiber sheets of various sizes and shapes were manufactured through an electrospinning process using polymers. When the electrospun surface of the dural substitutes of the present invention were treated with dura mater-derived stem cells, the stem cells exhibited significantly good adhesion and engraftment abilities as well as high angiogenesis ability. Therefore, a method and conditions for manufacturing dural substitutes have been established, and the dural substitute manufacturing method and the dural substitutes manufactured therefrom are expected to be effectively used.

Abstract: A display device includes a display panel including a first sub-pixel, a gate driver that provides a sensing control signal having a first voltage applied to the first sub-pixel in a first sensing period and a sensing control signal having a second voltage different from the first voltage applied to the first sub-pixel in a second sensing period, a data driver that receives a first sensing voltage from the first sub-pixel through a sensing line in the first sensing period and a second sensing voltage from the first sub-pixel through the sensing line in the second sensing period and a driving controller that controls the data driver and the gate driver and senses a characteristic of the first sub-pixel based on the first sensing voltage and the second sensing voltage.

Abstract: The present disclosure relates generally to vaccine constructs comprising a polynucleotide encoding a salmon alphavirus-like particle and uses thereof, including for inducing an immune response against salmonid alphavirus.

Abstract: A method for processing a sound signal using two acoustic sensors comprises receiving a training sound signal from the same sound source through a first acoustic sensor and a second acoustic sensor, which are arranged at separated locations, learning an artificial neural network model configured to set a bounded three-dimensional (3D) sound processing region based on the received training sound signal, the boundary of the 3D sound processing region being determined according to the relative positional relationship with the first acoustic sensor and the second acoustic sensor and processing a received target sound signal based on the 3D sound processing region using the learned artificial neural network model.

Abstract: The present disclosure relates to the detection of beta amyloid protein as an Alzheimer's disease-causing factor in the palatine tonsil and a use thereof and, more specifically, to the diagnosis of Alzheimer's disease by identifying the expression of beta amyloid and/or Staphylococcus aureus in a tonsillar sample. The present disclosure can diagnose Alzheimer's disease through the expression of beta amyloid and/or Staphylococcus aureus in a palatine tonsil tissue and, furthermore, can be very advantageously used for revealing the pathogenesis of Alzheimer's disease and for treating Alzheimer's disease.

Abstract: The present invention relates to a COVID-19 infection model using alveolar organoids. Respiratory virus-infected alveolar organoids produced according to the present invention are expected to be usefully used in preclinical or clinical drug screening and the like for the development of therapeutic agents for SARS-CoV-2 infection.

Abstract: The present invention relates to a crystalline form III represented by formula 1, a method for preparing the same, and a pharmaceutical composition comprising the same. The crystalline form III represented by formula 1 of the present invention may be characterized by XRPD patterns, TG/DTA profiles, an NMR spectrum, and/or DVS profiles.

Abstract: The present invention relates to a pharmaceutically acceptable salt of a sphingosine-1-phosphate receptor agonist and a crystalline form thereof, and more specifically, to a potassium salt or methanesulfonate of 1-[1-chloro-6-(3-chloro-1-isopropyl-1H-indazol-5-ylmethoxy)-3,4-dihydro-naphthalen-2-ylmethyl]-piperidine-4-carboxylic acid of formula 1, and a crystalline form thereof.

Abstract: An intelligent reflecting surfaces (IRS) system includes a plurality of reflectors for reflecting or refracting a reception signal according to characteristics thereof, a controller configured to control the characteristics of the plurality of reflectors to either reflect or refract the reception signal in a direction toward an antenna of a mobile device, and a substrate with a front side on which the plurality of reflectors arranged in a predetermined shape and the controller are mounted. The controller is designed to control the characteristics of the plurality of reflectors to maximize an area of the antenna to receive the reception signal, and the substrate is integrated into the mobile device.

Abstract: The invention relates to a new process for the purification of oligonucleotides which comprises the removal of an acid labile 5?hydroxy protecting group at the 5?-O-oligonucleotide terminus of the oligonucleotide by means of an on-column de-protection with an acid.

Abstract: A display device includes a display panel including a plurality of pixels, a cover window located on the display panel, and an optically clear bonding layer located between the display panel and the cover window, where the cover window includes, as a glass composition, 45 to 60 mol % SiO2, greater than 35 and equal to or less than 45 mol % B2O3, 3 to less than 9 mol % Na2O, and greater than 0 to less than 8 mol % Al2O3 based on total content of the cover window.

Abstract: The invention relates to a process for the production of a mixed P?O/P?S backbone oligonucleotide comprising a selective oxidation of an intermediary phosphite triester compound of formula I into a phosphodiester compound of formula II according to the scheme with an oxidation solution obtained by mixing iodine, an organic solvent and water, characterized in that the oxidation solution has been aged for a time period that is sufficient to selectively oxidize the phosphite triester compound of formula I into the phosphodiester compound of formula II without oxidizing the phosphorothioate internucleotide linkages.

Abstract: A dura mater-derived stem cell and a method of producing the same according to the present invention establish a method of isolating and producing stem cells from the dura mater by adding serum or a serum substitute, which is a culture supplement, to a conventionally used medium. The dura mater-derived stem cells produced by the production method of the present invention were confirmed to have excellent differentiation potency into mesenchymal and neurons and exhibit physical characteristics that enable them to maintain high cell viability when transplanted into cell therapeutic agents. Furthermore, they have been confirmed to possess inherent expression marker characteristics so that they can be effectively used in various applications including cell therapeutic agents.

Abstract: A battery management apparatus includes at least one capacitor respectively connected to at least one battery and a controller configured to apply current to the at least one capacitors to pre-charge the at least one capacitors, measure a voltage of each of the at least one capacitors, and control impedance measurement of the at least one batteries based on whether the voltage of the at least one capacitors is within a threshold range.

Abstract: A glass chemical strengthening furnace device is provided. A glass chemical strengthening furnace device includes, a bath, a first electrode on one side of the bath, and a second electrode on the other side of the bath and opposite to the first electrode. The first electrode is arranged to be separated from the second electrode with the bath therebetween.

Abstract: A display device includes a display panel including a first sub-pixel, a gate driver that provides a sensing control signal having a first voltage applied to the first sub-pixel in a first sensing period and a sensing control signal having a second voltage different from the first voltage applied to the first sub-pixel in a second sensing period, a data driver that receives a first sensing voltage from the first sub-pixel through a sensing line in the first sensing period and a second sensing voltage from the first sub-pixel through the sensing line in the second sensing period and a driving controller that controls the data driver and the gate driver and senses a characteristic of the first sub-pixel based on the first sensing voltage and the second sensing voltage.

Abstract: An intelligent reflecting surfaces (IRS) system includes a plurality of reflectors for reflecting or refracting a reception signal according to characteristics thereof, a controller configured to control the characteristics of the plurality of reflectors to either reflect or refract the reception signal in a direction toward an antenna of a mobile device, and a substrate with a front side on which the plurality of reflectors arranged in a predetermined shape and the controller are mounted. The controller is designed to control the characteristics of the plurality of reflectors to maximize an area of the antenna to receive the reception signal, and the substrate is integrated into the mobile device.

Abstract: A display device is disclosed that includes: a substrate including a display area and a non-display area, a pixel circuit layer disposed on the substrate, and a support structure disposed on the pixel circuit layer in the non-display area. The support structure includes a first support pattern, a second support pattern facing the first support pattern, and a third support pattern disposed between the first support pattern and the second support pattern.

Abstract: The present disclosure relates to a cell selection apparatus and method and, in particular, may provide an apparatus that classifies cells by using artificial intelligence, on the basis of the homogeneity of cells from an image pre-processed from image data obtained by capturing images of cells, and marks parts that have an important influence on the classification results, thereby increasing the accuracy of cell selection. In addition, a reliable selection basis can be provided by visualizing the basis for cell selection.

Abstract: A semiconductor device includes: a substrate including a cell region and a connection region, and extending in a first direction, wherein the connection region includes a through-region; active regions protruding vertically from the first surface of the substrate; source/drain regions spaced apart from each other on the substrate in the first direction, and including: first source/drain regions having a portion at least partially overlapping the through-region, and second source/drain regions disposed on at least one side of the active regions on the substrate; first gate structures intersecting the active regions; a front structure including a front conductive pattern; a backside structure including a backside conductive pattern; and a through-electrode structure filling the through-region, and electrically connected to the front conductive pattern and the backside conductive pattern, and wherein at least a portion of a lower region of the through-electrode structure is in contact with the first source/drain