Abstract: The present invention relates to a bi-specific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bi-specific antibody for the prevention, treatment and/or diagnosis of synucleinopathies associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.

Abstract: A mobile terminal of controlling playback speed of an image by using a touch gesture and a method for controlling playback speed of a mobile terminal are provided. A direction, such as fast-forward or rewind, and a multiple velocity of a video screen image are determined according to a direction and movement distance of a touch gesture made by moving a user's finger on a video reproduction screen image and the video screen image is moved according to the determined multiple velocity and direction at a corresponding position when the touch gesture is released such that the video can be fast-forwarded or rewound at various speeds.