Abstract: An HME unit for use in a breathing circuit is provided and includes an HME chamber that contains an HME member. The HME unit also includes an inner core for reception in the HME chamber. The inner core having at least one first opening formed therein and at least one second opening formed therein and spaced from the at least one first opening with an intermediate area being located between the at least one first opening and the at least one second opening. The HME member is disposed about the intermediate area of the inner core. The HME unit also includes a movable valve that has a valve member disposed within an interior bore of the inner core and being movable between a fully open position and a fully closed position that causes incoming breathing gas to flow across the HME member.

Abstract: A system for performing dynamic exposure analysis typically includes a classical computer apparatus and a quantum optimizer in communication with the classical computer apparatus. The classical computer apparatus is configured for gathering data from one or more data sources, processing the gathered data, via an artificial intelligence engine, to determine a change to an exposure rating, converting the gathered data into at least one matrix, converting the at least one matrix to at least one Qubit sequence, and transmitting the at least one Qubit sequence to a quantum optimizer. The quantum optimizer upon receiving the at least Qubit sequence, generates at least one random number based on one or more parameters stored in a configuration repository, computes the at least one Qubit sequence and the at least one random number to generate a real-time exposure rating, and transmits the real-time exposure rating to exposure analysis application.

Abstract: Embodiments of the present disclosure provide a system and method to abstract hardware access from applications running on a Baseboard Management Controller (BMC) using a hardware API service. According to one embodiment, an Information Handling System (IHS) includes executable instructions to expose an Application Program Interface (API) including a plurality of labels each uniquely identifying one of the hardware devices and a function to be provided by the one hardware device, and when an application executed on the BMC calls one of the labels, communicate with at least the one hardware device to perform the function specified by the one label.

Abstract: The present disclosure relates to novel immunogenic monovalent and multivalent polysaccharide-protein conjugate vaccine compositions comprising a polysaccharide selected from Salmonella serovar strains S. typhi; S. paratyphi A; S. typhimurium and S. enteritidis and alternative improved methods of polysaccharide fermentation, polysaccharide purification, polysaccharide-protein conjugation and stable formulation. The present disclosure further relates to methods for inducing an immune response in subjects against Salmonella and non-typhi related diseases and/or for reducing or preventing Salmonella typhi and non-typhi related diseases in subjects using the compositions disclosed herein. The vaccine elicits bactericidal antibodies and is useful for prevention of gastroenteritis, enteric and typhoid fever.

Abstract: One example method includes copying selected backup data from a secondary storage system to a provisioned primary storage volume, creating a snapshot of the primary storage volume, using the snapshot to create a thin clone volume, masking the thin clone volume, and mounting the thin clone volume, and recovering the backup data from the thin clone volume. The recovered backup data may be made available to a secondary workload that includes an enterprise application.

Abstract: 7H-Pyrrolo[2,3-d]pyrimidine compound for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of 7H-pyrrolo[2,3-d]pyrimidine compounds or analogs thereof, in the treatment of disorders characterized by overexpression of DYRK1A (e.g., cancer, Down syndrome, Alzheimer's disease, diabetes, viral infections, and osteoarthritis).

Abstract: User Equipment (UE) band capabilities are received from a UE. A set of frequency band combinations are determined for the UE based on the UE band capabilities. Each frequency band combination of the set of frequency band combinations includes a group of frequency bands, and a frequency band combination priority value. Further, one or more frequency band combinations are identified from the set of frequency band combinations based on a current frequency band of the UE and the frequency band combination priority value. The UE is configured to perform frequency measurements for a plurality of frequency bands based on the one or more identified frequency band combinations. The UE is dynamically facilitated to latch to at least one frequency band based on the frequency measurements of the plurality of frequency bands.

Abstract: A multi-band antenna element is provided with a stacked pair of a first low-band patch antenna element and a second low-band patch antenna element and also a high-band patch antenna element for operation across both a low band and a high band. An L-shaped probe in the multi-band antenna is configured to parasitically excite the high-band patch antenna element. A linear slot in the second low-band patch antenna element is configured to resonant in the high band.

Abstract: Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: The present disclosure compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the TEAD transcription factor, and are useful in the treatment of diseases related to the activity of TEAD transcription factor including, e.g., cancer and other diseases.

Abstract: The present technology provides intercloud connectivity as a service by discovering components of the organization's deployment in various sites, irrespective of the cloud provider, such that two sites can merely be selected along with a few standard options, and the controller can handle the complexity of instantiating a tunnel between the cloud sites automatically. Further, the controller can monitor the health of one or more tunnels between the cloud sites to automatically scale bandwidth up or down.

Abstract: Provided herein is a synthetic process for preparing a compound of Formula (1). The disclosure also provides useful intermediates and salts, amorphous and polymorph forms of the compound of Formula (1). These compounds are useful for various disease including cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, and osteoarthritis as well as Wnt-related diseases.

Abstract: Nanofiber segments comprising polymeric electrospun nanofibers are provided as well as methods of use thereof and methods of making.

Abstract: The system obtains a unique identifier of the vehicle and a unique identifier of a driver of the vehicle. The system generates an OTP using the unique identifier of the vehicle and the unique identifier of the driver of the vehicle and sends the OTP to the UE of the driver of the vehicle. The system authenticates the vehicle and the driver of the vehicle by receiving the OTP from the unique identifier of the UE. The system creates in a database an association between the unique identifier of the vehicle, the unique identifier of the driver of the vehicle, and the UE of the driver of the vehicle. The system detects that the UE is proximate to the parking garage where the vehicle is parked. Upon detecting that the UE is proximate to the parking garage, the system identifies the vehicle of the UE and delivers the vehicle.

Abstract: Fluid property sensors described herein may include a resonator configured to be immersed in a fluid or flowable medium and a vibrator coupled to the resonator, such that vibrations of the vibrator are transmitted to the resonator, e.g., to discourage and/or remove any buildup or deposits on the resonator and/or increase accuracy of the sensors. The frequency of the vibrator is configured to be substantially lower than the frequency of the resonator, such that operation of the resonator is not negatively affected. The vibrator may be located internal to, or external to, a chassis of the device.

Abstract: Various arrangements for using a short-range wireless communication link are presented herein. A wireless communication device can transmit data using an asynchronous connection-oriented logical transport (ACL) of the short-range wireless communication link. Monitoring for a high throughput event on the ACL of the short-range wireless communication link can be performed. Based on detecting the high throughput event on the ACL, a first physical layer (PHY) symbol rate of the ACL can be increased to a second PHY symbol rate.

Abstract: Various embodiments described herein relate to systems and methods for assessing a condition of a package in a facility. In this regard, first data from one or more first sensors is received once a worker picks the package at a first location in the facility. Further, based on the first data it is determined if the worker is holding the package. If the worker holds the package, second data is received from one or more second sensors such that the one or more second sensors are different from the one or more first sensors. Based on the second data, a package handling pattern for the package is determined. One or more notifications are provided to a mobile device associated with the worker if it is determined that the package handling pattern causes damage to the package.

Abstract: A method for optimizing bandwidth part (BWP) management for 5G wireless network includes: periodically analyzing, by a BWP analytics module located at one of near-real-time radio access network intelligent controller (near-RT RIC) or a distributed unit (DU) of a gNodeB, at least one of physical resource block (PRB) utilization difference, delay violation percentage corresponding to a percentage of logical channels not able to meet delay requirements for quality of service (QOS) profile assigned to the logical channels, throughput, and interference levels of a BWP to classify the BWP; periodically analyzing, by the BWP analytics module, at least one of PRB utilization, throughput, and delay requirements of at least one user equipment (UE); and categorizing, by the BWP analytics module, the at least one UE into one of a plurality of BWP classifications based on the analyzing of the at least one of PRB utilization, throughput, and delay requirements.

Abstract: A compute channel can have multiple computational circuit blocks coupled in series to form a pipeline. The compute channel can perform a computation on an input tensor to generate an output tensor based on an instruction. When the computational does not require all of the computational circuit blocks, the throughput of the compute channel can be increased by splitting the data elements of the input tensor into multiple input data streams. The multiple input data streams are provided to respective subsets of one or more computational circuit blocks in the pipeline using bypass circuitry of the computational circuit blocks, and the computation can be performed on multiple input data streams in the respective subsets of one or more computational circuit blocks to generate multiple output data streams corresponding to the output tensor.

Abstract: The present invention is directed to compound of formula (I) or a pharmaceutically acceptable salt or a stereoisomer or a tautomer thereof that is useful as MALT-1 inhibitors for the treatment of a disease or disorder dependent on MALT-1. The present invention also relates to a method of preparation of the compounds of the present invention and pharmaceutical compositions comprising the said compounds.