Abstract: Provided herein is a synthetic process for preparing a compound of Formula (1). The disclosure also provides useful intermediates and salts, amorphous and polymorph forms of the compound of Formula (1). These compounds are useful for various disease including cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, and osteoarthritis as well as Wnt-related diseases.

Abstract: The present technology provides intercloud connectivity as a service by discovering components of the organization's deployment in various sites, irrespective of the cloud provider, such that two sites can merely be selected along with a few standard options, and the controller can handle the complexity of instantiating a tunnel between the cloud sites automatically. Further, the controller can monitor the health of one or more tunnels between the cloud sites to automatically scale bandwidth up or down.

Abstract: A temperature dependent correction circuit includes a first supply source, a second supply source, a rectifying circuit, and a reference. The first supply source is configured to supply a first signal that varies with temperature along a first constant or continuously variable slope. The second supply source is configured to supply a second signal that varies with temperature along a second constant or continuously variable slope. The rectifying circuit is configured to receive the first and second signal, rectify the first signal to produce a first rectified signal, and add the first rectified signal to the second signal to produce a correction signal. The reference is configured to receive the correction signal.

Abstract: Fluid property sensors described herein may include a resonator configured to be immersed in a fluid or flowable medium and a vibrator coupled to the resonator, such that vibrations of the vibrator are transmitted to the resonator, e.g., to discourage and/or remove any buildup or deposits on the resonator and/or increase accuracy of the sensors. The frequency of the vibrator is configured to be substantially lower than the frequency of the resonator, such that operation of the resonator is not negatively affected. The vibrator may be located internal to, or external to, a chassis of the device.

Abstract: Nanofiber segments comprising polymeric electrospun nanofibers are provided as well as methods of use thereof and methods of making.

Abstract: The system obtains a unique identifier of the vehicle and a unique identifier of a driver of the vehicle. The system generates an OTP using the unique identifier of the vehicle and the unique identifier of the driver of the vehicle and sends the OTP to the UE of the driver of the vehicle. The system authenticates the vehicle and the driver of the vehicle by receiving the OTP from the unique identifier of the UE. The system creates in a database an association between the unique identifier of the vehicle, the unique identifier of the driver of the vehicle, and the UE of the driver of the vehicle. The system detects that the UE is proximate to the parking garage where the vehicle is parked. Upon detecting that the UE is proximate to the parking garage, the system identifies the vehicle of the UE and delivers the vehicle.

Abstract: Various arrangements for using a short-range wireless communication link are presented herein. A wireless communication device can transmit data using an asynchronous connection-oriented logical transport (ACL) of the short-range wireless communication link. Monitoring for a high throughput event on the ACL of the short-range wireless communication link can be performed. Based on detecting the high throughput event on the ACL, a first physical layer (PHY) symbol rate of the ACL can be increased to a second PHY symbol rate.

Abstract: Various embodiments described herein relate to systems and methods for assessing a condition of a package in a facility. In this regard, first data from one or more first sensors is received once a worker picks the package at a first location in the facility. Further, based on the first data it is determined if the worker is holding the package. If the worker holds the package, second data is received from one or more second sensors such that the one or more second sensors are different from the one or more first sensors. Based on the second data, a package handling pattern for the package is determined. One or more notifications are provided to a mobile device associated with the worker if it is determined that the package handling pattern causes damage to the package.

Abstract: A method for optimizing bandwidth part (BWP) management for 5G wireless network includes: periodically analyzing, by a BWP analytics module located at one of near-real-time radio access network intelligent controller (near-RT RIC) or a distributed unit (DU) of a gNodeB, at least one of physical resource block (PRB) utilization difference, delay violation percentage corresponding to a percentage of logical channels not able to meet delay requirements for quality of service (QOS) profile assigned to the logical channels, throughput, and interference levels of a BWP to classify the BWP; periodically analyzing, by the BWP analytics module, at least one of PRB utilization, throughput, and delay requirements of at least one user equipment (UE); and categorizing, by the BWP analytics module, the at least one UE into one of a plurality of BWP classifications based on the analyzing of the at least one of PRB utilization, throughput, and delay requirements.

Abstract: A compute channel can have multiple computational circuit blocks coupled in series to form a pipeline. The compute channel can perform a computation on an input tensor to generate an output tensor based on an instruction. When the computational does not require all of the computational circuit blocks, the throughput of the compute channel can be increased by splitting the data elements of the input tensor into multiple input data streams. The multiple input data streams are provided to respective subsets of one or more computational circuit blocks in the pipeline using bypass circuitry of the computational circuit blocks, and the computation can be performed on multiple input data streams in the respective subsets of one or more computational circuit blocks to generate multiple output data streams corresponding to the output tensor.

Abstract: Compounds and methods for their preparation and use as therapeutic or prophylactic agents, for example for treatment of bacterial or viral diseases by targeting Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1).

Abstract: The present invention is directed to compound of formula (I) or a pharmaceutically acceptable salt or a stereoisomer or a tautomer thereof that is useful as MALT-1 inhibitors for the treatment of a disease or disorder dependent on MALT-1. The present invention also relates to a method of preparation of the compounds of the present invention and pharmaceutical compositions comprising the said compounds.

Abstract: The present invention discloses a multi-agent robotic system for scrap collection and segregation is disclosed, featuring a foldable chassis with dynamic mechanical assemblies and integrated intelligence for precise waste management. The system includes articulated robotic arms equipped with grippers to collect and categorize materials, powered by dual-piston hydraulic actuators that drive telescopic folding segments with positional encoders for synchronized deployment. A control interface module, mounted on shock-dampening supports, comprises a multi-core CPU to process real-time data from sensors and actuators, ensuring precise operations. A wireless communication module enables encrypted coordination between multiple systems in the ecosystem. The mobility assembly integrates omnidirectional wheels with foldable axles and gyroscopic stabilization for seamless movement.

Abstract: An example method of managing guest time for a virtual machine (VM) supported by a hypervisor of a virtualized host computer includes: configuring, by the hypervisor, a central processing unit (CPU) of the host computer to trap, to the hypervisor, access by guest code in the VM to a physical counter and timer of the CPU; configuring, by the hypervisor, the guest code in the VM to use the physical counter and timer of the CPU rather than a virtual counter and timer of the CPU; trapping, at the hypervisor, an access to the physical counter and timer by the guest code; and executing, by the hypervisor, the access to the physical counter and timer on behalf of the guest code while compensating for an adjustment of a system count of the physical counter and timer to maintain the guest time as scaled with respect to frequency of the physical counter and timer.

Abstract: Techniques for improving system performance based on data characteristics are disclosed. A system may receive updates to a first data set at a first frequency. The system selects a first storage configuration, from a plurality of storage configurations, for storing the first data set based on the first frequency, and stores the first data set in accordance with the first storage configuration. The system may further receive updates to a second data set at a second frequency. The system selects a second storage configuration, from the plurality of storage configurations, for storing the second data set based on the second frequency, and stores the second data set in accordance with the second storage configuration. The second storage configuration is different than the first storage configuration.

Abstract: This disclosure generally relate to a method and system for network policy simulation in a distributed computing system. The present technology relates techniques that enable simulation of a new network policy with regard to its effects on the network data flow. By enabling a simulation data flow that is parallel and independent from the regular data flow, the present technology can provide optimized network security management with improved efficiency.

Abstract: A method of manufacturing a microfluidic analytical device comprising providing a top lamination layer and a bottom lamination layer, wherein each of the top lamination layer and bottom lamination layer comprises an outer layer and an inner layer, cutting out one or more channel spaces from the at least one of the top lamination layer and the bottom lamination layer, wherein the one or more channel spaces form a microfluidic path, positioning at least one middle layer between the top lamination layer and the bottom lamination layer, such that each of the two inner layers face the at least one middle layer, and subjecting the top lamination layer and the bottom lamination layer to a process, wherein the process allows both the inner layers to permeate substantially through the at least one middle layer.

Abstract: A rotary disc valve includes a rotatable assembly having a drive shaft with a flow control wall. The flow control wall includes an inner surface and an outer surface. The inner surface of defines a flow chamber within the drive shaft. A rotary disc is coupled to the drive shaft and is configured to rotate in unison therewith. The rotary disc includes an inner flow passage and an outer flow passage formed therethrough. The inner flow passage is always axially aligned with and fluidly coupled to the flow chamber of the drive shaft and the outer flow passage is always fluidly coupled to the outer surface of the flow control wall. A fixed disc sealing engages the rotary disc and includes a first flow opening, a second flow opening, and a third flow opening formed therethrough and disposed around the axis of rotation of the drive shaft.

Abstract: The present disclosure relates to a biodegradable polymer and a process for its preparation. The components of the biodegradable polymer of the present disclosure are obtained from natural and fossil resources and therefore the biodegradable polymer of the present disclosure has enhanced biodegradation properties. The process of the present disclosure is effective.

Abstract: A rotary disc valve includes a rotatable assembly having a drive shaft with a flow control wall. The flow control wall includes an inner surface and an outer surface. The inner surface of defines a flow chamber within the drive shaft. A rotary disc is coupled to the drive shaft and is configured to rotate in unison therewith. The rotary disc includes an inner flow passage and an outer flow passage formed therethrough. The inner flow passage is always axially aligned with and fluidly coupled to the flow chamber of the drive shaft and the outer flow passage is always fluidly coupled to the outer surface of the flow control wall. A fixed disc sealing engages the rotary disc and includes a first flow opening, a second flow opening, and a third flow opening formed therethrough and disposed around the axis of rotation of the drive shaft.