Patents by Inventor Sunil Kumar Vinubhai Gohel

Sunil Kumar Vinubhai Gohel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of duloxetine hydrochloride
    Patent number: 8269023
    Abstract: An improved process for synthesis of duloxetine hydrochloride (1) having chiral purity greater than 99.9% that is characterized by the following: (i) preparation of racemic condensed compound (RS)—N,N-di methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine (4) by reaction of racemic hydroxy compound (2) with 1-fluoronaphthalene (3) in presence of a base such as sodamide, potassium amide or potassium bis(trimethylsilyl)amide (KHDMS) in polar aprotic solvent, (ii) optical resolution of racemic condensed compound (5a+5b) with di-benzoyl-L-tartaric acid (7, DBTA, R=H) or di-para-anisoyl-L-tartaric acid (7, DATA, R=OCH3) to obtain crude (S)—N.N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine dibenzoyl tartarate salt (8a) or (S)—N.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: September 18, 2012
    Assignee: Lupin Ltd.
    Inventors: Rajinder Singh Siyan, Sunil Kumar Vinubhai Gohel, Girij Pal Singh
  • NOVEL PROCESS FOR PREPARATION OF DULOXETINE HYDROCHLORIDE
    Publication number: 20100105925
    Abstract: An improved process for synthesis of duloxetine hydrochloride (1) having chiral purity greater than 99.
    Type: Application
    Filed: March 5, 2008
    Publication date: April 29, 2010
    Applicant: LUPIN LIMITED
    Inventors: Rajinder Singh Siyan, Sunil Kumar Vinubhai Gohel, Girij Pal Singh