Patents by Inventor Sunney I. Chan

Sunney I. Chan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7799552
    Abstract: Among the inventions disclosed herein are: nucleic acid expression systems for bacteria having an intracytoplasmic membrane system, including, for example, methanotrophic bacteria; recombinant nucleic acid constructs comprising a pmo promoter operably linked to an expressible nucleic acid; cloning vectors suitable for making recombinant nucleic acid constructs and methods for the production of proteins such as membrane proteins.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: September 21, 2010
    Assignee: California Institute of Technology
    Inventors: Hiep-Hoa T. Nguyen, Sunney I. Chan
  • Patent number: 6967096
    Abstract: Thermostable peptidase enzyme derived from archaeon from the genus Pyrococcus is disclosed. The enzyme is produced from native or recombinant host cells and can be utilized in the biotechnology industry as a useful enzyme in sequencing reactions.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: November 22, 2005
    Assignee: California Institute of Technology
    Inventors: Timothy C. Cheng, Vij Ramakrishnan, Sunney I. Chan
  • Patent number: 6768122
    Abstract: A multiphoton excitaion microscope for simultaneously detecting differently colored fluorescence materials on biochips includes a multiphoton excitation source, objectives, and a plurality of detection channels. The biochip is hybridized and labeled with fluorescence materials for expressing hybridized biological signals. The multiphoton excitation source is focused to a light spot on the biochip to excite the fluorescence materials bound thereon. After that, the fluorescence emission at different wavelengths from the different fluorescent materials can be detected by the plural detection channels.
    Type: Grant
    Filed: June 4, 2002
    Date of Patent: July 27, 2004
    Assignee: National Taiwan University
    Inventors: Chen-Yuan Dong, Peter T. C. So, Sunney I. Chan
  • Patent number: 6767483
    Abstract: Inorganic-organic hybrid mixture sol-gel encapsulated lipid vesicles which are composed of silyl lipids or a mixture of silyl lipids and phospholipids are provided. The present invention also provides encapsulated Langmuir Blogget (LB) membranes and biological macromolecules. The sol-gel encapsulated lipid vesicles, LB membranes and proteins possess a higher stability than conventional vesicles. Inorganic-organic hybrid mixture sol-gels are provided as novel sol-gel materials possessing desirable mechanical and physicochemical properties. Also provided are methods of preparing encapsulated lipid vesicles, LB membranes and proteins. Methods of performing renal dialysis using compositions of the invention are also provided.
    Type: Grant
    Filed: August 21, 2001
    Date of Patent: July 27, 2004
    Assignee: California Institute of Technology
    Inventors: Michael H. B. Stowell, Guangyang Wang, Sunney I. Chan
  • Publication number: 20030222222
    Abstract: This invention provides a multiphoton excitaion microscope for simultaneously detecting differently colored fluorescence materials on biochips, which includes a multiphoton excitation source, objectives, and a plurality of detection channels. The biochip is hybridized and labeled with fluorescence materials for expressing hybridized biological signals. The multiphoton excitation source is focused to a light spot on the biochip to excite the fluorescence materials bound thereon. After that, the fluorescence emission at different wavelengths from the different fluorescent materials can be detected by the plural detection channels.
    Type: Application
    Filed: June 4, 2002
    Publication date: December 4, 2003
    Applicant: National Taiwan University
    Inventors: Chen-Yuan Dong, Peter T.C. So, Sunney I. Chan
  • Publication number: 20030032141
    Abstract: Among the inventions disclosed herein are: nucleic acid expression systems for bacteria having an intracytoplasmic membrane system, including, for example, methanotrophic bacteria; recombinant nucleic acid constructs comprising a pmo promoter operably linked to an expressible nucleic acid; cloning vectors suitable for making recombinant nucleic acid constructs and methods for the production of proteins such as membrane proteins.
    Type: Application
    Filed: July 22, 2002
    Publication date: February 13, 2003
    Inventors: Hiep-Hoa T. Nguyen, Sunney I. Chan
  • Publication number: 20020106779
    Abstract: Thermostable peptidase enzyme derived from archaeon from the genus Pyrococcus is disclosed. The enzyme is produced from native or recombinant host cells and can be utilized in the biotechnology industry as a useful enzyme in sequencing reactions.
    Type: Application
    Filed: September 24, 2001
    Publication date: August 8, 2002
    Applicant: California Institute of Technology, a California corporation
    Inventors: Timothy C. Cheng, Vij Ramakrishnan, Sunney I. Chan
  • Publication number: 20020020931
    Abstract: Inorganic-organic hybrid mixture sol-gel encapsulated lipid vesicles which are composed of silyl lipids or a mixture of silyl lipids and phospholipids are provided. The present invention also provides encapsulated Langmuir Blogget (LB) membranes and biological macromolecules. The sol-gel encapsulated lipid vesicles, LB membranes and proteins possess a higher stability than conventional vesicles. Inorganic-organic hybrid mixture sol-gels are provided as novel sol-gel materials possessing desirable mechanical and physicochemical properties. Also provided are methods of preparing encapsulated lipid vesicles, LB membranes and proteins. Methods of performing renal dialysis using compositions of the invention are also provided.
    Type: Application
    Filed: August 21, 2001
    Publication date: February 21, 2002
    Applicant: California Institute of Technology
    Inventors: Michael H.B. Stowell, Guangyang Wang, Sunney I. Chan
  • Patent number: 6294367
    Abstract: Thermostable peptidase enzyme derived from archaeon from the genus Pyrococcus is disclosed. The enzyme is produced from native or recombinant host cells and can be utilized in the biotechnology industry as a useful enzyme in sequencing reactions.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: September 25, 2001
    Assignee: California Institute of Technology
    Inventors: Timothy C. Cheng, Vij Ramakrishnan, Sunney I. Chan
  • Patent number: 6284163
    Abstract: Inorganic-organic hybrid mixture sol-gel encapsulated lipid vesicles which are composed of silyl lipids or a mixture of silyl lipids and phospholipids are provided. The present invention also provides encapsulated Langmuir Blogget (LB) membranes and biological macromolecules. The sol-gel encapsulated lipid vesicles, LB membranes and proteins possess a higher stability than conventional vesicles. Inorganic-organic hybrid mixture sol-gels are provided as novel sol-gel materials possessing desirable mechanical and physicochemical properties. Also provided are methods of preparing encapsulated lipid vesicles, LB membranes and proteins. Methods of performing renal dialysis using compositions of the invention are also provided.
    Type: Grant
    Filed: January 24, 1997
    Date of Patent: September 4, 2001
    Assignee: California Institute of Technology
    Inventors: Michael H. B. Stowell, Guangyang Wang, Sunney I. Chan
  • Patent number: 5767288
    Abstract: The invention relates to dithiane adducts of substituted benzoins and substituted benzoins derived therefrom each of which are useful as protecting groups, photolabile linkers, and fluorescent probes.
    Type: Grant
    Filed: January 5, 1996
    Date of Patent: June 16, 1998
    Assignee: California Institute of Technology
    Inventors: Ronald S. Rock, Michael H. B. Stowell, Sunney I. Chan