Patents by Inventor Sun Yeou Kim

Sun Yeou Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240325469
    Abstract: The present invention relates to a novel Lactobacillus paracasei NK112 strain that has the effect of preventing or treating cognitive dysfunction and intestinal dysfunction. In addition, the present invention relates to a composition for prevention, treatment, or alleviation of cognitive dysfunction and intestinal dysfunction, comprising a Lactobacillus paracasei NK112 strain, a Cuscuta australis R.Br. extract, and a Cuscuta japonica Choisy extract. The strain and the composition, of the present invention, exhibit efficacy in increasing the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), alleviating intestinal inflammation, and the like, and thus can be effectively used in the prevention or treatment of cognitive dysfunction and intestinal dysfunction.
    Type: Application
    Filed: June 5, 2024
    Publication date: October 3, 2024
    Inventors: Miwon SOHN, Jin Gyu CHOI, Sinyeon KIM, Sang Cheol PARK, Dong Hyun KIM, Sun Yeou KIM, Seong Min HONG, Myung Sook OH, In Gyoung JU, Choong Hwan LEE
  • Publication number: 20240329058
    Abstract: The present invention relates to a biomarker for neurodegenerative diseases, comprising glycotoxin, a specific protein bound to glycotoxin, or a glycotoxin-specific protein complex, and more specifically, the biomarker permits non-invasive rapid detection of a specific fluorescence from the skin surface and therefore can be used in early detection of cognitive impairment, and for a confirmed case of cognitive impairment, measures the mRNA expression level and protein level of the biomarker from living tissues such as skin and blood, and therefore is advantageously utilized in prediction, diagnosis, and the like of neurodegenerative diseases such as Alzheimer's disease and the like.
    Type: Application
    Filed: April 8, 2022
    Publication date: October 3, 2024
    Inventors: Sun Yeou KIM, Keun-A CHANG, Seung Young SEO, Min Cheol KANG, Min Ju KANG, Kyu Hwan SHIM, Da-Eun JEONG
  • Publication number: 20240124399
    Abstract: The present invention relates to a novel indole derivative and a use thereof. The novel indole derivative according to the present invention traps methylglyoxal (MGO), which is a main precursor of advanced glycation end products, and thus can be effectively used for preventing, improving, or treating diseases related to advanced glycation end products.
    Type: Application
    Filed: December 11, 2023
    Publication date: April 18, 2024
    Inventors: Seung Yong SEO, San Ha LEE, Jung Eun LEE, Joon Seong HUR, Sang Il KWON, Sun Yeou KIM, Seong Min HONG, Min Cheol KANG, Myoung Gyu PARK, Eun Joo LEE
  • Publication number: 20240124404
    Abstract: The present invention relates to a composition for preventing, improving, or treating diseases related to advanced glycation end products, comprising an indole derivative or a pharmaceutically acceptable salt thereof. Specifically, the composition of the present invention possesses the effect of trapping methylglyoxal (MGO), which is a main precursor of advanced glycation end products, and thus can be effectively used for preventing, improving, or treating diseases related to advanced glycation end products.
    Type: Application
    Filed: December 11, 2023
    Publication date: April 18, 2024
    Inventors: Seung Yong SEO, San Ha LEE, Jung Eun LEE, Joon Seong HUR, Sang Il KWON, Sun Yeou KIM, Seong Min HONG, Min Cheol KANG, Myoung Gyu PARK, Eun Joo LEE
  • Publication number: 20230365501
    Abstract: The present invention relates to: a novel 4-methoxy-2-phenethyl isoindolin-1-one derivative compound having the ability to promote the increase of nerve growth factor, the ability to promote the growth of nerve cells, and antineuritic activity; and a composition for preventing, improving and treating neurological diseases, comprising the same.
    Type: Application
    Filed: September 17, 2021
    Publication date: November 16, 2023
    Applicants: CNG BIO CO., LTD., CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Jaekyung JUNG, Mi Kyeong LEE, Dae Hee LEE, Jae Kang LEE, Sun Yeou KIM, Da Hye YOON, Seong Min HONG
  • Publication number: 20230331672
    Abstract: The present invention relates to: a novel 6-methoxy-2-phenethyl isoindolin-1-one derivative compound having the ability to promote the increase of nerve growth factor, the ability to promote the growth of nerve cells, and antineuritic activity; and a composition for preventing, improving and treating neurological diseases, comprising the same.
    Type: Application
    Filed: September 17, 2021
    Publication date: October 19, 2023
    Applicants: CNG BIO CO., LTD., CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Jaekyung JUNG, Mi Kyeong LEE, Dae Hee LEE, Jae Kang LEE, Sun Yeou KIM, Da Hye YOON, Seong Min HONG
  • Patent number: 11058740
    Abstract: The present disclosure relates to a composition for preventing, alleviating or treating stress diseases, containing a Platycodon grandiflorum extract as an active ingredient, and, more specifically, to a food composition for preventing or alleviating stress diseases or a pharmaceutical composition for preventing and treating stress diseases, both of which contain a Platycodon grandiflorum extract and a Citrus aurantium extract as active ingredients. A method of the present disclosure can be used for the preparation of an agent for treating depression and anxiety, which are stress diseases, with few side effects because of the use of a natural material, and a health functional food having effects of alleviating depression, anxiety and fatigue, which are stress diseases.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: July 13, 2021
    Assignee: SUNG KYUN BIOTECH CO., LTD.
    Inventors: Mi Rim Jin, Do Heon Lee, Sun Yeou Kim
  • Publication number: 20210113648
    Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or herb mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health functional foods preventive and curative of diabetic peripheral neuropathy.
    Type: Application
    Filed: September 30, 2020
    Publication date: April 22, 2021
    Applicant: DONG-A ST CO., LTD.
    Inventors: Soon-Hoe KIM, Mi-Won SON, Sang-Zin CHOI, Hye-Ju KIM, Ja-Young RYU, Sun-Yeou KIM
  • Publication number: 20200397845
    Abstract: This invention relates to a pharmaceutical composition and a health functional food for preventing or improving neurodegenerative disorders comprising mixed herb extracts of Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 (w/w). The herb extracts mixed Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 have the synergetic effects on increasing the amount of nerve growth factor in vivo, increasing the neural cell proliferation, promoting the formation of neuritis and enhancing cognitive abilities. Thus, the herb extracts of the present invention may be used for a pharmaceutical composition and a health functional food for preventing or treating neurodegenerative disorders.
    Type: Application
    Filed: June 4, 2020
    Publication date: December 24, 2020
    Applicant: DONG-A-ST Co., Ltd.
    Inventors: Soon Hoe KIM, Mi-Won SON, Sang-Zin CHOI, Hye-Ju KIM, Ja-Young RYU, Sun-Yeou KIM
  • Patent number: 10836734
    Abstract: The present invention relates to a novel spiroquinone derivative compound, a production method thereof, and a pharmaceutical composition for preventing or treating neurological disorders which contains the compound as an active ingredient.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: November 17, 2020
    Assignees: GACHON UNIVERSITY OF INDUSTRY—ACADEMIC COOPERATION FOUNDATION, GIL MEDICAL CENTER
    Inventors: Mi-Hyun Kim, Sun Yeou Kim, Sang-Yoon Lee, Venkanna Arramshetti, Kang Kim, Kyohee Cho, Prema Dhorma Lama
  • Patent number: 10813973
    Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or herb mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health functional foods preventive and curative of diabetic peripheral neuropathy.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: October 27, 2020
    Assignee: DONG-A ST CO., LTD.
    Inventors: Soon-Hoe Kim, Mi-Won Son, Sang-Zin Choi, Hye-Ju Kim, Ja-Young Ryu, Sun-Yeou Kim
  • Patent number: 10709752
    Abstract: This invention relates to a pharmaceutical composition and a health functional food for preventing or improving neurodegenerative disorders comprising mixed herb extracts of Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 (w/w). The herb extracts mixed Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 have the synergetic effects on increasing the amount of nerve growth factor in vivo, increasing the neural cell proliferation, promoting the formation of neuritis and enhancing cognitive abilities. Thus, the herb extracts of the present invention may be used for a pharmaceutical composition and a health functional food for preventing or treating neurodegenerative disorders.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: July 14, 2020
    Assignee: DONG-A ST CO., LTD.
    Inventors: Soon-Hoe Kim, Mi-Won Son, Sang-Zin Choi, Hye-Ju Kim, Ja-Young Ryu, Sun-Yeou Kim
  • Publication number: 20200113962
    Abstract: The present disclosure relates to a composition for preventing, alleviating or treating stress diseases, containing a Platycodon grandiflorum extract as an active ingredient, and, more specifically, to a food composition for preventing or alleviating stress diseases or a pharmaceutical composition for preventing and treating stress diseases, both of which contain a Platycodon grandiflorum extract and a Citrus aurantium extract as active ingredients. A method of the present disclosure can be used for the preparation of an agent for treating depression and anxiety, which are stress diseases, with few side effects because of the use of a natural material, and a health functional food having effects of alleviating depression, anxiety and fatigue, which are stress diseases.
    Type: Application
    Filed: April 18, 2018
    Publication date: April 16, 2020
    Applicant: SUNG kyun BIOTECH CO.. LTD,
    Inventors: Mi Rim JIN, Do Heon LEE, Sun Yeou KIM
  • Patent number: 10398747
    Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or her mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health function foods preventive and curative of diabetic peripheral neuropathy.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: September 3, 2019
    Assignee: Dong-A St Co., Ltd.
    Inventors: Soon-Hoe Kim, Mi-Won Son, Sang-Zin Choi, Hye-Ju Kim, Ja-Young Ryu, Sun-Yeou Kim
  • Publication number: 20180327370
    Abstract: The present invention relates to a novel spiroquinone derivative compound, a production method thereof, and a pharmaceutical composition for preventing or treating neurological disorders which contains the compound as an active ingredient
    Type: Application
    Filed: July 24, 2018
    Publication date: November 15, 2018
    Applicants: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, GIL MEDICAL CENTER
    Inventors: Mi-hyun Kim, Sun Yeou Kim, Venkanna Arramshetti, Kang Kim, Kyohee Cho, Prema Dhorma Lama, Sang-Yoon Lee
  • Publication number: 20180318377
    Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or her mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health function foods preventive and curative of diabetic peripheral neuropathy.
    Type: Application
    Filed: July 12, 2018
    Publication date: November 8, 2018
    Inventors: Soon-Hoe KIM, Mi-Won SON, Sang-Zin CHOI, Hye-Ju KIM, Ja-Young RYU, Sun-Yeou KIM
  • Patent number: 9844521
    Abstract: The present invention provides a pharmaceutical composition for preventing or treating learning disorders, memory disorders, Parkinson's disease, or ischemic cerebrovascular disease, which comprises a ginger extract or shogaol; and a pharmaceutically acceptable carrier. And also, the present invention provides a food composition for improving learning disorders or memory disorders or alleviating the symptoms of learning disorders or memory disorders which comprises a ginger extract or shogaol as an active ingredient, or a food composition for improving learning or memory which comprises a ginger extract or shogaol as an active ingredient.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: December 19, 2017
    Assignee: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Sun-Yeou Kim, Sang-Keun Ha, Jong-Hoon Ryu, Myung-Sook Oh, Seo-Young Jeong
  • Patent number: 9840716
    Abstract: The present invention relates to resveratrol-enriched transgenic rice for biosynthesizing resveratrol at high concentration, in which resveratrol synthase genes are expressibly inserted into the 12th chromosome of natural rice, and seed of rice produced therefrom. Further, the present invention relates to a health functional food composition, an animal feed composition, and a pharmaceutical composition for preventing and improving a metabolic disease, including seed of rice produced from the resveratrol-enriched transgenic rice for biosynthesizing resveratrol, in which resveratrol synthase genes are expressibly inserted into the 12th chromosome of natural rice. The seed of rice produced from resveratrol-enriched transgenic rice into which resveratrol synthase genes are inserted, containing high a concentration of resveratrol of the present invention exhibits remarkably superior effects compared to when the same amount of resveratrol is simply ingested.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: December 12, 2017
    Assignee: Republic of Korea (Management: Rural Development Administration)
    Inventors: So Hyeon Baek, Woon Chul Shin, Young Jun Mo, Bo Kyong Kim, Seong Tshool Hong, Sun Yeou Kim, Soon Jong Kweon
  • Publication number: 20170216390
    Abstract: This invention relates to a pharmaceutical composition and a health functional food for preventing or improving neurodegenerative disorders comprising mixed herb extracts of Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 (w/w). The herb extracts mixed Dioscorea Rhizoma and Dioscorea nipponica in a weight ratio of 3.5:1 have the synergetic effects on increasing the amount of nerve growth factor in vivo, increasing the neural cell proliferation, promoting the formation of neuritis and enhancing cognitive abilities. Thus, the herb extracts of the present invention may be used for a pharmaceutical composition and a health functional food for preventing or treating neurodegenerative disorders.
    Type: Application
    Filed: April 10, 2017
    Publication date: August 3, 2017
    Inventors: Soon-Hoe KIM, Mi-Won SON, Sang-Zin CHOI, Hye-Ju KIM, Ja-Young RYU, Sun-Yeou KIM
  • Publication number: 20170209515
    Abstract: Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma:Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or herb mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health functional foods preventive and curative of diabetic peripheral neuropathy.
    Type: Application
    Filed: April 10, 2017
    Publication date: July 27, 2017
    Inventors: Soon-Hoe KIM, Mi-Won SON, Sang-Zin CHOI, Hye-Ju KIM, Ja-Young RYU, Sun-Yeou KIM