Patents by Inventor Suping Zhou

Suping Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • O-(substituted benzyl) phosphoramidate compounds and therapeutic use
    Patent number: 9095599
    Abstract: This application discloses novel phosphoramidate and phosphonoamidate prodrugs of nucleosides, nucleotides, C-nucleosides, C-nucleotides, phosphonates, and other alcohol-containing drugs; use of these prodrugs for treatment of infectious diseases and cancers, in particular, liver infections and cancers; and methods of preparing these novel phosphoramidate and phosphonoamidate prodrugs.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: August 4, 2015
    Assignee: Nanjing Molecular Research, Inc.
    Inventors: Junbiao Chang, Zheng Wang, Suping Zhou
  • 2',3'-Dideoxy-2'-alpha-Fluoro-2'-beta-C-Methylnucleosides and Prodrugs Thereof
    Publication number: 20140315850
    Abstract: The present invention is made to fulfill the foregoing need. Since most of antiHN nucleosides are 2?,3?-dideoxynucleosides that have been proved to be excellent substrates of kinases for the phosphorylations. 2?,3?-Dideoxy-2,-a-fluoro-2?-{3-C-methyl-nucleosides can be considered as one unique class of 2?,3?-dideoxynucleosides to be good substrate of kinases because fluorine mimics hydrogen. It also can be considered as ribo-nucleosides to incorporate into RNA of HCV because 2?-fluorine-a mimics 2?-a-OH group.
    Type: Application
    Filed: July 19, 2012
    Publication date: October 23, 2014
    Applicant: Nanjing Molecular Research, Inc.
    Inventors: Qiang Huang, Suping Zhou, Junbiao Chang
  • O-(SUBSTITUTED BENZYL) PHOSPHORAMIDATE COMPOUNDS AND THERAPEUTIC USE
    Publication number: 20140038916
    Abstract: This application discloses novel phosphoramidate and phosphonoamidate prodrugs of nucleosides, nucleotides, C-nucleosides, C-nucleotides, phosphonates, and other alcohol-containing drugs; use of these prodrugs for treatment of infectious diseases and cancers, in particular, liver infections and cancers; and methods of preparing these novel phosphoramidate and phosphonoamidate prodrugs.
    Type: Application
    Filed: December 30, 2011
    Publication date: February 6, 2014
    Applicant: Nanjing Molecular Research, Inc.
    Inventors: Zheng Wang, Suping Zhou