Abstract: A system, medium, and method including obtaining a plurality of positions for multiple components defined by a plan; obtaining a set of constraints that express limitations for the multiple components at the plurality of positions, the constraints being applicable to a plan where the multiple components synchronously change their positions with time to traverse a prescribed sequence of the plurality of positions, at least one of the multiple components being further constrained to change its position over time by staying within a predefined tolerance to a predefined smooth function of position over time between different positions; determining a trajectory of position and a minimum duration in which the multiple components completely synchronously traverse the prescribed sequence of positions while satisfying the constraints for the multiple components; and generating a record of the determined trajectory of position and the minimum duration for the plurality of components.

Abstract: A system includes determination of a first sub-matrix of a projection matrix which describes a geometrical relationship between points of a three-dimensional coordinate system of the imaging system and points of a two-dimensional coordinate system of an image detector, determination of a second sub-matrix of the projection matrix, where the first and second sub-matrixes comprise a decomposition of the projection matrix, conversion of a first point of the two-dimensional coordinate system to a first point of the three-dimensional coordinate system based on the first and second sub-matrixes, determination of an updated first sub-matrix of an updated projection matrix, where the updated projection matrix describes a second geometrical relationship between points of the three-dimensional coordinate system and points of the two-dimensional coordinate system, and conversion of a second point of the two-dimensional coordinate system to a second point of the three-dimensional coordinate system based on the updated fi

Abstract: A system includes determination of a first sub-matrix of a projection matrix which describes a geometrical relationship between points of a three-dimensional coordinate system of the imaging system and points of a two-dimensional coordinate system of an image detector, determination of a second sub-matrix of the projection matrix, where the first and second sub-matrixes comprise a decomposition of the projection matrix, conversion of a first point of the two-dimensional coordinate system to a first point of the three-dimensional coordinate system based on the first and second sub-matrixes, determination of an updated first sub-matrix of an updated projection matrix, where the updated projection matrix describes a second geometrical relationship between points of the three-dimensional coordinate system and points of the two-dimensional coordinate system, and conversion of a second point of the two-dimensional coordinate system to a second point of the three-dimensional coordinate system based on the updated fi

Abstract: A system includes determination of a first sub-matrix of a projection matrix which describes a geometrical relationship between points of a three-dimensional coordinate system of the imaging system and points of a two-dimensional coordinate system of an image detector, determination of a second sub-matrix of the projection matrix, where the first and second sub-matrixes comprise a decomposition of the projection matrix, conversion of a first point of the two-dimensional coordinate system to a first point of the three-dimensional coordinate system based on the first and second sub-matrixes, determination of an updated first sub-matrix of an updated projection matrix, where the updated projection matrix describes a second geometrical relationship between points of the three-dimensional coordinate system and points of the two-dimensional coordinate system, and conversion of a second point of the two-dimensional coordinate system to a second point of the three-dimensional coordinate system based on the updated fi

Abstract: A system includes acquisition of a three-dimensional computed tomography image of a patient volume at a computed tomography scanner, acquisition of projection images of the patient volume located at an isocenter of a linear accelerator, and determination of a transformation between a coordinate system of the linear accelerator and a coordinate system of the three-dimensional computed tomography image based on the projection images.

Abstract: A system includes obtaining of a reference projection image of a target volume at an isocenter of a computed tomography scanner; obtaining of a plurality of two-dimensional fluoroscopic images by the computed tomography scanner of at least a portion of the target volume at the isocenter of the computed tomography scanner; displaying the reference projection image and the plurality of two-dimensional fluoroscopic images in a combined view; measuring a two-dimensional contour of a projection of a movement of the target volume in the combined view; and determining a true contour of the movement in a plane containing a point-of-interest within the target volume based on the two-dimensional contour of the projection of the movement.

Abstract: Some embodiments include obtaining a projection image of a plurality of fiducials associated with a coordinate system irradiated by a radiotherapy radiation source at a plurality of discrete locations on a trajectory path model, determination of a projection matrix from projection images of the fiducials irradiated by the radiotherapy radiation source at each of the discrete locations, determination of the actual coordinate of the radiotherapy radiation source in the coordinate system associated with the fiducials at the plurality of discrete locations based on the determined projection matrices, and correlating the trajectory path model of the radiotherapy radiation source to the determined actual position of the radiotherapy radiation source at the discrete locations.

Abstract: A system includes acquisition of a three-dimensional computed tomography image of a patient volume at a computed tomography scanner, acquisition of projection images of the patient volume located at an isocenter of a linear accelerator, and determination of a transformation between a coordinate system of the linear accelerator and a coordinate system of the three-dimensional computed tomography image based on the projection images.

Abstract: Some embodiments include obtaining a projection image of a plurality of fiducials associated with a coordinate system irradiated by a radiotherapy radiation source at a plurality of discrete locations on a trajectory path model, determination of a projection matrix from projection images of the fiducials irradiated by the radiotherapy radiation source at each of the discrete locations, determination of the actual coordinate of the radiotherapy radiation source in the coordinate system associated with the fiducials at the plurality of discrete locations based on the determined projection matrices, and correlating the trajectory path model of the radiotherapy radiation source to the determined actual position of the radiotherapy radiation source at the discrete locations.

Abstract: Some embodiments include determination of a first projection image of a phantom based on first imaging geometry parameters associated with a first radiation-based imaging system and on a virtual model of the phantom, acquisition of a second projection image of the phantom based on radiation emitted from the first radiation-based imaging system, the phantom located at a first position and determination of a difference between the first projection image and the second projection image. Second imaging geometry parameters are determined based on the first imaging geometry parameters and the difference between the first projection image and the second projection image, a third projection image of the phantom is determined based on the second imaging geometry parameters and on the virtual model of the phantom, and a fourth projection image of the phantom located at the first position is acquired based on radiation emitted from the first radiation-based imaging system.

Abstract: Some embodiments include determination of a first projection image of a phantom based on first imaging geometry parameters associated with a first radiation-based imaging system and on a virtual model of the phantom, acquisition of a second projection image of the phantom based on radiation emitted from the first radiation-based imaging system, the phantom located at a first position, and determination of a difference between the first projection image and the second projection image. Second imaging geometry parameters are determined based on the first imaging geometry parameters and the difference between the first projection image and the second projection image, a third projection image of the phantom is determined based on the second imaging geometry parameters and on the virtual model of the phantom, and a fourth projection image of the phantom located at the first position is acquired based on radiation emitted from the first radiation-based imaging system.

Abstract: In some embodiments, a method includes receiving, in a processor, information indicative of (i) a treatment plan defining planned treatment beams, (ii) a patient volume relative to a reference, (iii) ideal intersections of the planned treatment beams with the patient volume at the time the patient is to be treated, (iv) any constraints that prevent achievement of the recommended repositioning using only the patient support, (v) an allowable change to a gantry position from a planned value and an allowable change to a collimator position from a planned value; defining, in the processor, a plurality of alternatives based at least in part on the information indicative of any constraints of the patient support and the information indicative of allowable movement of the gantry and collimator, each alternative defining a modified patient support position and modified beams, each modified beam being based at least in part on a respective one of the planned treatment beams, the change to the position of the gantry fo

Abstract: In some embodiments, a method includes receiving, in a processor, information indicative of (i) a treatment plan defining planned treatment beams, (ii) a patient volume relative to a reference, (iii) ideal intersections of the planned treatment beams with the patient volume at the time the patient is to be treated, (iv) any constraints that prevent achievement of the recommended repositioning using only the patient support, (v) an allowable change to a gantry position from a planned value and an allowable change to a collimator position from a planned value; defining, in the processor, a plurality of alternatives based at least in part on the information indicative of any constraints of the patient support and the information indicative of allowable movement of the gantry and collimator, each alternative defining a modified patient support position and modified beams, each modified beam being based at least in part on a respective one of the planned treatment beams, the change to the position of the gantry fo

Abstract: A method for reconstructing an object subject to cone beam passing through the object and generating projection images of the object using a graphic processing unit (GPU). The method applies a non-linear curvature-based smoothing filter to the projection images. The method applies a high-pass filter to the curvature-smoothed images. The method backprojects the projection images into an output volume using voxel driven backprojection. The method removes cupping artifacts from the output volume convolving every slice with a Butterworth kernel and adding the result to the slice weighted by a scaling factor.

Abstract: A method for operating a digital computer to provide a display for inputting values needed in a computation and displaying the results of the computation. The method starts by displaying a graphical element on a computer screen, said graphical element being capable of representing the magnitude of one of the input values. The magnitude is changed by using a pointing device to manipulate a specified region on the graphical element. The computer monitors the graphical element for any change therein. Upon detecting such a change, the computer displays the results of the computation in a first graphical display in response to the detected change in the input value represented by the graphical element. The computer then returns to monitoring the graphical element for another change. In one embodiment of the present invention, the graphical elements are arranged to form a second graphical display.