Patents by Inventor Supratim Datta

Supratim Datta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of hydrolyzing a cellulose using halophilic, thermostable and ionic liquids tolerant cellulases
    Patent number: 9862982
    Abstract: The present invention provides for an isolated or recombinant polypeptide comprising an amino acid sequence having at least 70% identity with the amino acid sequence of a Halorhabdus utahensis cellulase, such as Hu-CBH1, wherein said amino acid sequence has a halophilic thermostable and/or thermophilic cellobiohydrolase (CBH) activity. In some embodiments, the polypeptide has a CBH activity that is resistant to up to about 20% of ionic liquids. The present invention also provides for compositions comprising and methods using the isolated or recombinant polypeptide.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: January 9, 2018
    Assignees: The Regents of the University of California, Sandia Corporation
    Inventors: Tao Zhang, Supratim Datta, Blake A. Simmons, Edward M. Rubin
  • Thermophilic cellobiohydrolase
    Patent number: 9624482
    Abstract: The present invention provides for a composition comprising a polypeptide comprising a first amino acid sequence having at least 70% identity with the amino acid sequence of Csac GH5 wherein said first amino acid sequence has a thermostable or thermophilic cellobiohydrolase (CBH) or exoglucanase activity.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: April 18, 2017
    Assignee: Sandia Corporation
    Inventors: Rajat Sapra, Joshua I. Park, Supratim Datta, Blake A. Simmons
  • Useful halophilic, thermostable and ionic liquids tolerant cellulases
    Publication number: 20170029856
    Abstract: The present invention provides for an isolated or recombinant polypeptide comprising an amino acid sequence having at least 70% identity with the amino acid sequence of a Halorhabdus utahensis cellulase, such as Hu-CBH1, wherein said amino acid sequence has a halophilic thermostable and/or thermophilic cellobiohydrolase (CBH) activity. In some embodiments, the polypeptide has a CBH activity that is resistant to up to about 20% of ionic liquids. The present invention also provides for compositions comprising and methods using the isolated or recombinant polypeptide.
    Type: Application
    Filed: May 25, 2016
    Publication date: February 2, 2017
    Applicants: The Regents of the University of California, Sandia Corporation
    Inventors: Tao Zhang, Supratim Datta, Blake A. Simmons, Edward M. Rubin
  • Useful halophilic, thermostable and ionic liquids tolerant cellulases
    Patent number: 9376728
    Abstract: The present invention provides for an isolated or recombinant polypeptide comprising an amino acid sequence having at least 70% identity with the amino acid sequence of a Halorhabdus utahensis cellulase, such as Hu-CBH1, wherein said amino acid sequence has a halophilic thermostable and/or thermophilic cellobiohydrolase (CBH) activity. In some embodiments, the polypeptide has a CBH activity that is resistant to up to about 20% of ionic liquids. The present invention also provides for compositions comprising and methods using the isolated or recombinant polypeptide.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: June 28, 2016
    Assignees: The Regents of the University of California, Sandia Corporation
    Inventors: Tao Zhang, Supratim Datta, Blake A. Simmons, Edward M. Rubin
  • Thermostable cellulases, and mutants thereof, capable of hydrolyzing cellulose in ionic liquid
    Patent number: 9322042
    Abstract: The present invention provides for a composition comprising an ionic liquid and a thermostable cellulose, and a method of hydrolyzing a cellulose, comprising: (a) providing a composition comprising a solution comprising an ionic liquid and a cellulose, and (b) introducing a thermostable cellulase to the solution, such that the cellulose is hydrolyzed by the cellulase. The present invention also provides for a Thermatoga maritima thermostable cellulase mutant with increased cellulase activity.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: April 26, 2016
    Assignees: The Regents of the University of California, Sandia Corporation
    Inventors: Rajat Sapra, Supratim Datta, Zhiwei Chen, Bradley M. Holmes, Blake A. Simmons, Harvey W. Blanch
  • Useful halophilic, thermostable and ionic liquids tolerant cellulases
    Publication number: 20130023015
    Abstract: The present invention provides for an isolated or recombinant polypeptide comprising an amino acid sequence having at least 70% identity with the amino acid sequence of a Halorhabdus utahensis cellulase, such as Hu-CBH1, wherein said amino acid sequence has a halophilic thermostable and/or thermophilic cellobiohydrolase (CBH) activity. In some embodiments, the polypeptide has a CBH activity that is resistant to up to about 20% of ionic liquids. The present invention also provides for compositions comprising and methods using the isolated or recombinant polypeptide.
    Type: Application
    Filed: June 11, 2012
    Publication date: January 24, 2013
    Applicants: The Regents of the University of California, Sandia Corporation
    Inventors: Tao Zhang, Supratim Datta, Blake A. Simmons, Edward M. Rubin
  • THERMOSTABLE CELLULASES, AND MUTANTS THEREOF, CAPABLE OF HYDROLYZING CELLULOSE IN IONIC LIQUID
    Publication number: 20120129227
    Abstract: The present invention provides for a composition comprising an ionic liquid and a thermostable cellulose, and a method of hydrolyzing a cellulose, comprising: (a) providing a composition comprising a solution comprising an ionic liquid and a cellulose, and (b) introducing a thermostable cellulase to the solution, such that the cellulose is hydrolyzed by the cellulase. The present invention also provides for a Thermatoga maritima thermostable cellulase mutant with increased cellulase activity.
    Type: Application
    Filed: April 23, 2010
    Publication date: May 24, 2012
    Applicants: Sandia Corporation, The Regents of the University of California
    Inventors: Rajat Sapra, Supratim Datta, Zhiwei Chen, Bradley M. Holmes, Blake A. Simmons, Harvey W. Blanch
  • Novel thermophilic cellobiohydrolase
    Publication number: 20110207182
    Abstract: The present invention provides for a composition comprising a polypeptide comprising a first amino acid sequence having at least 70% identity with the amino acid sequence of Csac GH5 wherein said first amino acid sequence has a thermostable or thermophilic cellobiohydrolase (CBH) or exoglucanase activity.
    Type: Application
    Filed: September 28, 2010
    Publication date: August 25, 2011
    Applicant: SANDIA CORPORATION
    Inventors: Rajat Sapra, Joshua I. Park, Supratim Datta, Blake A. Simmons