Abstract: A sensor for selectively capturing a targeted cell type in a fluid includes an engineered surface. The engineered surface includes a substrate, a non-adhesive element disposed on at least a portion of a substrate, and an adhesive element disposed on the substrate. The sensor also includes a flow channel in operative contact with the engineered surface; and a detector configured to detect the targeted cell type captured on the engineered surface. Also described is a method for selectively capturing target cell types using the engineered surface.

Abstract: A sensor for selectively capturing a targeted cell type in a fluid includes an engineered surface. The engineered surface includes a substrate, a non-adhesive element disposed on at least a portion of a substrate, and an adhesive element disposed on the substrate. The sensor also includes a flow channel in operative contact with the engineered surface; and a detector configured to detect the targeted cell type captured on the engineered surface. Also described is a method for selectively capturing target cell types using the engineered surface.

Abstract: The invention is comprised, in part, of a surface that contains more than one component or construct. Such heterogenous surface compositions and configurations, related systems and methods for sensing particle or analyte interaction therewith can selectively and/or differentially interact with a range of particles/analytes, in lieu of specific molecular sensor-analyte interactions for each particle. These interactions of various analytes or particles can differ sufficiently in strength and range between multiple analyte types or particles to effect a separation of analytes or particles mixtures, in a way that requires no sensing or detection. With incorporation of a sensing mechanism, discrimination/detection of different compounds within an analyte mixture can be accomplished.

Abstract: The invention is comprised, in part, of a surface that contains more than one component or construct. Such heterogenous surface compositions and configurations, related systems and methods for sensing particle or analyte interaction therewith can selectively and/or differentially interact with a range of particles/analytes, in lieu of specific molecular sensor-analyte interactions for each particle. These interactions of various analytes or particles can differ sufficiently in strength and range between multiple analyte types or particles to effect a separation of analytes or particles mixtures, in a way that requires no sensing or detection. With incorporation of a sensing mechanism, discrimination/detection of different compounds within an analyte mixture can be accomplished.