Patents by Inventor SURAVI CHAKRABARTY

SURAVI CHAKRABARTY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL ANTHRANILIC AMIDES AND THE USE THEREOF
    Publication number: 20230100458
    Abstract: Disclosed are anthranilic amide derivatives having the formula: Compositions are disclosed that include the anthranilic amide derivatives and the use of the anthranilic amide derivatives for the manufacture of a medicament. Further disclosed are methods of inhibiting or treating cancer, inhibiting or reversing an epithelial to mesenchymal cellular transition, and/or inhibiting MEK1/2 and/or MEK 5 enzymatic activity in a subject by administering to the subject an effective amount of a disclosed anthranilic amide derivative.
    Type: Application
    Filed: August 26, 2022
    Publication date: March 30, 2023
    Inventors: Suravi CHAKRABARTY, Patrick T. FLAHERTY, Darlene MONLISH, Jane E. CAVANAUGH, Matthew E. BUROW, Steven ELLIOTT, Van T. HOANG
  • Anthranilic amides and the use thereof
    Patent number: 11465978
    Abstract: Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the anthranilic amide derivatives for the manufacture of a medicament. Further disclosed are methods of inhibiting or treating cancer, inhibiting or reversing an epithelial to mesenchymal cellular transition, and/or inhibiting MEK1/2 and/or MEK 5 enzymatic activity in a subject by administering to the subject an effective amount of a disclosed anthranilic amide derivative.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: October 11, 2022
    Assignees: THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, DUQUESNE UNIVERSITY OF THE HOLY GHOST
    Inventors: Suravi Chakrabarty, Patrick T. Flaherty, Darlene Monlish, Jane E. Cavanaugh, Matthew E. Burow, Steven Elliott, Van T. Hoang
  • Carboxylic acid ester prodrug inhibitors of MEK
    Patent number: 10654792
    Abstract: The invention generally relates to compounds having structure I: wherein x represents alkyl, aryl or het-aryl, each of y independently represents hydrogen or halogen and z represents hydrogen or alkyl. Further, said compounds are inhibitors of MEK 1, 2 and 5. Furthermore, the invention includes methods of making said compounds, compositions including said compounds and uses for inhibiting MEK 1, 2 and 5.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: May 19, 2020
    Assignee: DUQUESNE UNIVERSITY OF THE HOLY SPIRIT
    Inventors: Suravi Chakrabarty, Darlene Monlish, Patrick Flaherty, Jane E. Cavanaugh, Sneha Potdar
  • CARBOXYLIC ACID ESTER PRODRUG INHIBITORS OF MEK
    Publication number: 20170096388
    Abstract: The invention generally relates to compounds having structure I: wherein x represents alkyl, aryl or het-aryl, each of y independently represents hydrogen or halogen and z represents hydrogen or alkyl. Further, said compounds are inhibitors of MEK 1, 2 and 5. Furthermore, the invention includes methods of making said compounds, compositions including said compounds and uses for inhibiting MEK 1, 2 and 5.
    Type: Application
    Filed: December 19, 2016
    Publication date: April 6, 2017
    Applicant: DUQUESNE UNIVERSITY OF THE HOLY GHOST
    Inventors: SURAVI CHAKRABARTY, DARLENE MONLISH, PATRICK FLAHERTY, JANE E. CAVANAUGH, SNEHA POTDAR
  • Carboxylic acid ester prodrug inhibitors of MEK
    Patent number: 9556112
    Abstract: The invention generally relates to compounds having structure I: wherein x represents alkyl, aryl or het-aryl, each of y independently represents hydrogen or halogen and z represents hydrogen or alkyl. Further, said compounds are inhibitors of MEK 1, 2 and 5. Furthermore, the invention includes methods of making said compounds, compositions including said compounds and uses for inhibiting MEK 1, 2 and 5.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: January 31, 2017
    Assignee: Duquesne University of the Holy Ghost
    Inventors: Suravi Chakrabarty, Darlene Monlish, Patrick Flaherty, Jane E. Cavanaugh, Sneha Potdar
  • NOVEL ANTHRANILIC AMIDES AND THE USE THEREOF
    Publication number: 20160221975
    Abstract: Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the anthranilic amide derivatives for the manufacture of a medicament. Further disclosed are methods of inhibiting or treating cancer, inhibiting or reversing an epithelial to mesenchymal cellular transition, and/or inhibiting MEK1/2 and/or MEK 5 enzymatic activity in a subject by administering to the subject an effective amount of a disclosed anthranilic amide derivative.
    Type: Application
    Filed: September 11, 2014
    Publication date: August 4, 2016
    Inventors: Suravi CHAKRABARTY, Patrick T. FLAHERTY, Darlene MONLISH, Jane E. CAVANAUGH, Mattthew E. BUROW, Steven ELLIOTT, Van T. HOANG
  • CARBOXYLIC ACID ESTER PRODRUG INHIBITORS OF MEK
    Publication number: 20140135519
    Abstract: The invention generally relates to compounds having structure I: wherein x represents alkyl, aryl or het-aryl, each of y independently represents hydrogen or halogen and z represents hydrogen or alkyl. Further, said compounds are inhibitors of MEK 1, 2 and 5. Furthermore, the invention includes methods of making said compounds, compositions including said compounds and uses for inhibiting MEK 1, 2 and 5.
    Type: Application
    Filed: November 15, 2013
    Publication date: May 15, 2014
    Applicant: DUQUESNE UNIVERSITY OF THE HOLY GHOST
    Inventors: SURAVI CHAKRABARTY, Darlene Monlish, Patrick Flaherty, Jane E. Cavanaugh, Sneha Potdar