Abstract: The present disclosure is directed to solid and salt forms of inhibitors of the CBP/p300 family of bromodomains made up of salts and crystalline forms of Formula (I). The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains (e.g., certain forms of cancer), and methods of synthesis of these compounds.

Abstract: This disclosure relates to techniques for a wireless device to determine a radio access technology availability indicator to present. A wireless device may establish a wireless link with a cellular network via a cell that operates according to a first radio access technology. The wireless device may determine if access to the cellular network is also available via a cell that operates according to a second radio access technology, by configuration by the serving cell or from another standalone cell. The wireless device may select a radio access technology availability indicator to present based at least in part on determining if access to the cellular network is also available via a cell that operates according to the second radio access technology.

Abstract: Disclosed are quinoline and quinazoline compounds which modulate the activity of the gated ion channels. Compounds that modulate these gated ion channels are useful in the treatment of diseases and disorders related to pain, inflammation, the neurological system, the gastrointestinal system and genitourinary system. Preferred compounds include quinoline or quinazoline derivatives substituted at the 4-position via N(H), C(O) or O moieties.

Abstract: The present disclosure provides crystalline solid forms, spray-dried dispersions and pharmaceutical compositions, including solid oral dosage forms, of (S)-1-(5-[2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl]-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl)-3-hydroxy-2-phenylpropan-1-one (“Compound 1”), and preparation methods thereof.

Abstract: Certain aspects of the present disclosure provide techniques for committing log data in an application to a log data repository. An example method generally includes receiving, from an application, data to be committed to a remote storage location. A type of the received data is determined. The type of the received data is generally associated with a prioritization level and a compression mechanism to be used in committing the data to the remote storage location. An application execution context associated with the received data is determined. At a dispatch time associated with the prioritization level of the received data and the application execution context associated with the received data, a compressed data payload is generated and transmitted to the remote storage location. Generally, to compress the data payload, at least the received data is generally compressed based on the determined compression mechanism.

Abstract: Techniques are disclosed relating to handover of WLAN voice calls to one or more cellular networks. In some embodiments, a device is configured to perform voice communications over one or more wireless local area networks, communicate with a first network using a first cellular radio access technology (RAT), and communicate with a second network using a second cellular RAT. The device may store, based on communications via the first network, information indicating that the first network does not support voice communications for the apparatus. The device may handover a voice call from a wireless local network directly to the second cellular RAT, based on the stored information and without handover of the voice call to the first cellular RAT, based on call conditions on the wireless local area network.

Abstract: Systems and methods for displaying search item scores and related information for easier search result selection. In one aspect, the method includes receiving a search request for a software component, retrieving a programming language information of the software component, retrieving an ecosystem information of the software component, retrieving a licensing information of the software component, retrieving a quality score of the software component, retrieving a security score of the software component, retrieving details of sources and associated details of the software component, dynamically generating a results information widget including information associated with the software component, and searching, based on the retrieved information, internet sources to assimilate associated information of the software components.

Abstract: A method for distributed application distribution may include: (1) receiving, at a first decentralized marketplace instance in a distributed ledger network and from a first node of the plurality of nodes, the first node associated with a distributed application creator, a distributed application; (2) making available, by the first decentralized marketplace instance, the distributed application to decentralized marketplace instances, wherein the first node is configured to provide the distributed application to a second node, the second node associated with a distributed application collaborator; (3) receiving, at a second decentralized marketplace instance and from the second node, a modified version of the distributed application; and (4) making available, by the second decentralized marketplace instance, the modified version of the distributed application to the decentralized marketplace instances, wherein the second node is configured to provide the distributed application to a third node, the third node a

Abstract: Systems and methods are provided for recording video of a driver in a vehicle and a surrounding visual field of the driver. The system includes a detachable body coupled to a windshield of a vehicle. The system further includes three or more cameras coupled to the detachable body. The three or more cameras are configured to capture surrounding views from the detachable body. One of the three or more cameras faces a driver seat of the vehicle in response to the detachable body being coupled to the windshield of the vehicle. The video may be processed by the system, the cloud, or a combination of them.

Abstract: Systems, methods, and articles of manufacture for controlling a compression action of a trash receptacle of an aircraft lavatory. Generally, the systems, methods, and articles of manufacture disclosed and described herein facilitate controlled opening and closing actuations of a flap of a trash receptacle of an aircraft lavatory, and a compression action after detection of at least the closing actuation of trash deposits in the trash receptacle to increase the interior volume of the trash receptacle. By controlling the closing actuations of the flap and compression actions of trash deposits, hygiene and sanitation of the lavatory are improved, odors are prevented from dispersing throughout the lavatory and/or cabin of the aircraft, and fire hazards are reduced.

Abstract: Provided here are methods of using a mutated patatin-like phospholipase II? (“pPLAII?,” renamed here MATRILINEAL) to induce haploid induction in plants, cloning a pPLAII? to induce haploid induction in plants, and genetically engineering a plant to contain a mutated pPLAII?. Also provided are methods of applying topical and spray chemicals, lipids, and RNAi molecules to plants during pollination in order to induce haploid production. Further provided are methods of chemically treating plants during pollination to induce haploids while also reducing embryo abortion and increasing seed set.

Abstract: An engine component comprises one or more thermal barrier coatings applied to one or more areas of the engine component. The thermal barrier coatings reduce the temperature rate of change of the areas to which the thermal barrier coating is applied. Reducing the temperature rate of change can help reduce lattice structure damage caused by different temperatures in different areas of the engine component. The thermal barrier coating can be applied as a monolithic layer on a surface of the engine component or can be applied in different areas using patterns. The patterns allow for the tuning of the performance characteristics (temperature rate of change) of the areas of the engine component and can help reduce defect propagation, such as cracks, in the thermal barrier coating from one area of the thermal barrier coating to other areas of the thermal barrier coating.

Abstract: The present invention relates to nimbolide analogs useful as anti-cancer agents and preparation thereof. Particularly the present invention relates to nimbolide analogs of general formula I. wherein, ring M is any ring selected from the group consisting of substituted or unsubstituted aryl, heteroaryl, cycloalkyl and heterocyclic; A and B are selected from the group consisting of C, O, N, S and H; R1, R2, R3, R4, R5 and R6 are selected from the group consisting of C1-C6 alkyl, aryl, heteroaryl, C1-C7 cycloalkyl, heteroalkyl, hydrogen, hydroxy, alkoxy, nitro, halogen, amino, alkylamino, aryl amino and cyano; wherein each of these groups may be further substituted with one or more substituents selected from the group consisting of hydrogen, hydroxy, halogen, cyano, alkyl amino, aryl amino, alkoxy, amino, nitro, aldehyde, carboxylic acid and ester.

Abstract: Techniques for migrating live broadcast streams from one data center to another data center are described herein. A data center from a plurality of data centers may be determined to transfer live streaming video content from a first data center to the data center. A separate live streaming session for each live streaming session being broadcast by the first data center may be generated by communicating with an ingest service server that receives media content used to generate each separate live streaming session and the live streaming session. Each separate live streaming session may be routed to the candidate data center. A determination that each separate live streaming session of the candidate data center is synchronized with each live streaming session of the first data center may be made. An update to a mapping of IP addresses to redirect requests from the first data center to the candidate data center.

Abstract: A method for verifying an electronic circuit design includes detecting a first issue in a register transfer level description of the electronic circuit design and receiving a selection to waive the first issue. The method also includes capturing the selection to waive the first issue in a memory, detecting, by a processing device, a second issue while generating a netlist or gate level description of the electronic circuit design, and based on determining that the selection to waive the first issue indicated in the memory applies to the second issue, suppressing or ignoring the second issue.

Abstract: An actuator control system for an assembly including moveable components such as a passenger seat. The system includes a first motor having a first rotating shaft, a second motor having a second rotating shaft, and a plurality of gear assemblies including a gear disposed between the shafts. A controller operates to move each gear independently between a neutral position and a rotationally engaged position with one of the rotating shafts. Each gear is coupled to a flexible shaft rotationally coupled to an actuator for moving the moveable component. In use, a singular controller and the two motors control N number of actuators.

Abstract: Systems and methods are provided for recording video of a driver in a vehicle and a surrounding visual field of the driver. The system includes a detachable body coupled to a windshield of a vehicle. The system further includes three or more cameras coupled to the detachable body. The three or more cameras are configured to capture surrounding views from the detachable body. One of the three or more cameras faces a driver seat of the vehicle in response to the detachable body being coupled to the windshield of the vehicle. The video may be processed by the system, the cloud, or a combination of them.

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heterocyclic and heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

Abstract: An engine component comprises one or more thermal barrier coatings applied to one or more areas of the engine component. The thermal barrier coatings reduce the temperature rate of change of the areas to which the thermal barrier coating is applied. Reducing the temperature rate of change can help reduce lattice structure damage caused by different temperatures in different areas of the engine component. The thermal barrier coating can be applied as a monolithic layer on a surface of the engine component or can be applied in different areas using patterns. The patterns allow for the tuning of the performance characteristics (temperature rate of change) of the areas of the engine component and can help reduce defect propagation, such as cracks, in the thermal barrier coating from one area of the thermal barrier coating to other areas of the thermal barrier coating.

Abstract: Systems and methods are provided for recording video of a driver in a vehicle and a surrounding visual field of the driver. The system includes a detachable body coupled to a windshield of a vehicle. The system further includes three or more cameras coupled to the detachable body. The three or more cameras are configured to capture surrounding views from the detachable body. One of the three or more cameras faces a driver seat of the vehicle in response to the detachable body being coupled to the windshield of the vehicle. The video may be processed by the system, the cloud, or a combination of them.