Patents by Inventor Suresh Eknath Kurhade

Suresh Eknath Kurhade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kifunensine derivatives
    Patent number: 12024515
    Abstract: The present disclosure relates to compounds according to Formula I (I) or a pharmaceutically acceptable salt and/or solvate thereof, as well as compositions including such compounds and uses thereof, where R1 is an unsubstituted C1-C12 alkyl; and R2, R3, and R4 are each independently H or —C(O)—(unsubstituted C1-C12 alkyl). Among other things, the present disclosure evidences that the significant upregulation of CD20 by the inhibition of a-mannosidase enzymes by compounds of the present technology potentiates the activity of anti-CD20 mAbs and importantly sensitize cell lines that are resistant to the action of these antibodies.
    Type: Grant
    Filed: January 22, 2022
    Date of Patent: July 2, 2024
    Assignee: UNIVERSITY OF KANSAS
    Inventors: Mark Patrick Farrell, Suresh Eknath Kurhade, Patrick Andrew Ross, Jack Douglas Weiner, Fei Philip Gao
  • Glycoside derivatives and uses thereof
    Patent number: 9895389
    Abstract: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: February 20, 2018
    Assignee: Novartis AG
    Inventors: Gregory Raymond Bebernitz, Mark G. Bock, Dumbala Srinivas Reddy, Atul Kashinath Hajare, Vinod Vyavahare, Sandeep Bhausaheb Bhosale, Suresh Eknath Kurhade, Videsh Salunkhe, Nadim S. Shaikh, Debnath Bhuniya, P. Venkata Palle, Lili Feng, Jessica Liang
  • GLYCOSIDE DERIVATIVES AND USES THEREOF
    Publication number: 20170042925
    Abstract: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
    Type: Application
    Filed: April 20, 2016
    Publication date: February 16, 2017
    Inventors: Gregory Raymond Bebernitz, Mark G. Bock, Dumbala Srinivas Reddy, Atul Kashinath Hajare, Vinod Vyavahare, Sandeep Bhausaheb Bhosale, Suresh Eknath Kurhade, Videsh Salunkhe, Nadim S. Shaikh, Debnath Bhuniya, P. Venkata Palle, Lili Feng, Jessica Liang
  • Glycoside derivatives and uses thereof
    Patent number: 8828951
    Abstract: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: September 9, 2014
    Assignee: Novartis AG
    Inventors: Gregory Raymond Bebernitz, Mark G. Bock, Dumbala Srinivas Reddy, Atul Kashinath Hajare, Vinod Vyavahare, Sandeep Bhausaheb Bhosale, Suresh Eknath Kurhade, Videsh Salunkhe, Nadim S. Shaikh, Debnath Bhuniya, P. Venkata Palle, Lili Feng, Jessica Liang
  • Glycoside derivatives and uses thereof
    Patent number: 8466114
    Abstract: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: June 18, 2013
    Assignee: Novartis AG
    Inventors: Gregory Raymond Bebernitz, Mark G. Bock, Dumbala Srinivas Reddy, Atul Kashinath Hajare, Vinod Vyavahare, Sandeep Bhausaheb Bhosale, Suresh Eknath Kurhade, Videsh Salunkhe, Nadim S. Shaikh, Debnath Bhuniya, P. Venkata Palle, Lili Feng, Jessica Liang
  • Glycoside derivative and uses thereof
    Patent number: 8394772
    Abstract: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
    Type: Grant
    Filed: October 20, 2010
    Date of Patent: March 12, 2013
    Assignee: Novartis AG
    Inventors: Gregory Raymond Bebernitz, Mark Gary Bock, Debnath Bhuniya, Laxmikant Datrange, Suresh Eknath Kurhade, P. Venkata Palle, Dumbala Srinivas Reddy
  • GLYCOSIDE DERIVATIVE AND USES THEREOF
    Publication number: 20120196813
    Abstract: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
    Type: Application
    Filed: October 20, 2010
    Publication date: August 2, 2012
    Applicant: NOVARTIS AG
    Inventors: Gregory Raymond Bebernitz, Mark Gary Bock, Debnath Bhuniya, Laxmikant Datrange, Suresh Eknath Kurhade, P. Venkata Palle, Dumbala Srinivas Reddy
  • Glycoside derivatives and uses thereof
    Patent number: 8163704
    Abstract: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: April 24, 2012
    Assignee: Novartis AG
    Inventors: Gregory Raymond Bebernitz, Mark G. Bock, Dumbala Srinivas Reddy, Atul Kashinath Hajare, Vinod Vyavahare, Sandeep Bhausaheb Bhosale, Suresh Eknath Kurhade, Videsh Salunkhe, Nadim S. Shaikh, Debnath Bhuniya, P. Venkata Palle, Lili Feng, Jessica Liang
  • GLUCOSIDE DERIVATIVES AND USES THEREOF
    Publication number: 20110269700
    Abstract: The present invention relates to compounds of formula I and pharmaceutically acceptable salts thereof, and to formulations and uses of the compounds of formula (I) in the treatment of metabolic disorders.
    Type: Application
    Filed: September 17, 2009
    Publication date: November 3, 2011
    Inventors: P. Venkata Palle, Debnath Bhuniya, Dumbala Srinivas Reddy, Suresh Eknath Kurhade
  • GLYCOSIDE DERIVATIVES AND USES THEREOF
    Publication number: 20110230403
    Abstract: The present invention relates to compounds of formula I and pharmaceutically acceptable salts, to formulations and uses of the compounds of formula (I) in the treatment of metabolic disorders.
    Type: Application
    Filed: September 17, 2009
    Publication date: September 22, 2011
    Applicant: NOVARTIS AG
    Inventors: P. Venkata Palle, Dumbala Srinivas Reddy, Suresh Eknath Kurhade, Debnath Bhuniya
  • Glycoside derivatives and uses thereof
    Patent number: RE49080
    Abstract: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: May 24, 2022
    Assignee: Novartis AG
    Inventors: Gregory Raymond Bebernitz, Mark G. Bock, Dumbala Srinivas Reddy, Atul Kashinath Hajare, Vinod Vyavahare, Sandeep Bhausaheb Bhosale, Suresh Eknath Kurhade, Videsh Salunkhe, Nadim S. Shaikh, Debnath Bhuniya, P. Venkata Palle, Lili Feng, Jessica Liang