Patents by Inventor Suresh Hasbe

Suresh Hasbe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pure intermediate
    Patent number: 9150524
    Abstract: The present invention relates to an improved process for the preparation of Letrozole (I) and its synthetic intermediate 4-[(1-(1,2,4-triazoly)methyl]benzonitrile (III). In particular, it relates to a process to prepare Letrozole and its intermediate (III) substantially free from regioisomeric impurities. The present invention further relates to acid addition salts of 4-[(1-(1,2,4-triazoly)methyl]benzonitrile (III) such as the oxalate salt, and also to Letrozole (I), the intermediate (III) and salts thereof preparable by the processes of the present invention.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: October 6, 2015
    Assignee: Generics [UK] Limited
    Inventors: Vinayak Govind Gore, Vinay Kumar Shukla, Sandeep Mekde, Suresh Hasbe, Shreyas Bhandari, Dhananjay Shinde, Madhukar Shaligram Patil
  • Process for the preparation of lenalidomide
    Patent number: 8946265
    Abstract: The present invention relates to improved processes for preparing 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione (I) (lenalidomide) and its intermediate 3-(1-oxo-4-nitro-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione. The present invention further relates to improved processes for preparing lenalidomide crystalline form A, use of said crystalline form A as an active pharmaceutical ingredient or as an intermediate in the preparation of further crystalline or amorphous forms of lenalidomide, compositions comprising lenalidomide crystalline form A and their use in the treatment of disease.
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: February 3, 2015
    Assignee: Generics [UK] Limited
    Inventors: Vinayak Govind Gore, Vinay Kumar Shukla, Shreyas Shrikant Bhandari, Suresh Hasbe
  • Pure Intermediate
    Publication number: 20130203826
    Abstract: The present invention relates to an improved process for the preparation of Letrozole (I) and its synthetic intermediate 4-[(1-(1,2,4-triazoly)methyl]benzonitrile (III). In particular, it relates to a process to prepare Letrozole and its intermediate (III) substantially free from regioisomeric impurities. The present invention further relates to acid addition salts of 4-[(1-(1,2,4-triazoly)methyl]benzonitrile (III) such as the oxalate salt, and also to Letrozole (I), the intermediate (III) and salts thereof preparable by the processes of the present invention.
    Type: Application
    Filed: August 26, 2011
    Publication date: August 8, 2013
    Applicant: Generics [UK] Limited
    Inventors: Vinayak Govind Gore, Vinay Kumar Shukla, Sandeep Mekde, Suresh Hasbe, Shreyas Bhandari, Dhananjay Shinde, Madhukar Shaligram Patil
  • PROCESS
    Publication number: 20120071509
    Abstract: The present invention relates to improved processes for preparing 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione (I) (lenalidomide) and its intermediate 3-(1-oxo-4-nitro-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione. The present invention further relates to improved processes for preparing lenalidomide crystalline form A, use of said crystalline form A as an active pharmaceutical ingredient or as an intermediate in the preparation of further crystalline or amorphous forms of lenalidomide, compositions comprising lenalidomide crystalline form A and their use in the treatment of disease.
    Type: Application
    Filed: March 1, 2010
    Publication date: March 22, 2012
    Inventors: Vinayak Govind Gore, Vinay Kumar Shukla, Sheryas Bhandari, Suresh Hasbe