Patents by Inventor Suresh Kapadia

Suresh Kapadia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARING MACROCYCLIC COMPOUNDS
    Publication number: 20060205638
    Abstract: Disclosed is a process for preparing a macrocyclic compound of the formula (I) wherein a hydroxyl-substituted macrocyclic compound of formula (3) is reacted with a sulfonyl-substituted compound of formula QUIN: The compounds of formula (I) are potent active agents for the treatment of hepatitis C virus (HCV) infection.
    Type: Application
    Filed: March 6, 2006
    Publication date: September 14, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Carl Busacca, Fabrice Gallou, Nizar Haddad, Azad Hossain, Suresh Kapadia, Jianxiu Liu, Chris Senanayake, Xudong Wei, Nathan Yee
  • Process for preparing acyclic HCV protease inhibitors
    Publication number: 20050267151
    Abstract: Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection: The disclosed processes use SNAr-type coupling reactions between peptidic compounds having a hydroxyproline moiety of the following formula: and halogenated or sulfonated bromoquinoline compounds.
    Type: Application
    Filed: May 23, 2005
    Publication date: December 1, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Carl Busacca, Rogelio Frutos, Nizar Haddad, Suresh Kapadia, Jon Lorenz, Anjan Saha, Chris Senanayake, Xudong Wei
  • Dipeptide synthesis
    Publication number: 20050113572
    Abstract: Disclosed are processes of making dipeptide compounds of formula(I) as further described in the detailed description section:
    Type: Application
    Filed: October 27, 2004
    Publication date: May 26, 2005
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Carl Busacca, Nizar Haddad, Suresh Kapadia, Lana Smith Keenan, Jon Lorenz, Chris Senanayake, Xudong Wei
  • Synthesis of alpha-methyl, alpha-substituted amino acids
    Patent number: 6043376
    Abstract: An improved process for making chiral, .alpha.-methylated, .alpha.-substituted amino acids of the formula I ##STR1## wherein Y is a hydrogen atom and R.sub.2 is the residue of a natural or unnatural amino acid, in which process an oxazolidinone of the formula II ##STR2## is formed by reacting a protected amino acid of the formula IA ##STR3## wherein Y is a protecting group, with an aldehyde of the formula RCHO, or an equivalent thereof, in the presence of a chlorinating agent and a Lewis acid.The group R.sub.2 is introduced into the oxazolidinone intermediate of formula II in a conventional manner, and subsequent hydrolysis and deprotection, both carried out in a conventional manner, yield the chiral, .alpha.-methylated, .alpha.-substituted amino acid.
    Type: Grant
    Filed: June 29, 1999
    Date of Patent: March 28, 2000
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Denice M. Spero, Suresh Kapadia, Elio Napolitano
  • 5,6-Heteroaryl-dipyrido(2,3-B:3', 2'-F) azepines and their use in the prevention or treatment of HIV infection
    Patent number: 5919779
    Abstract: "There are disclosed compounds of the formula I, II or III ##STR1## wherein A and D are carbon or nitrogen and B is oxygen, sulfur or nitrogen which are useful in the prevention or treatment of HIV infection.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: July 6, 1999
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: John R. Proudfoot, Karl D. Hargrave, Suresh Kapadia
  • 2-heteroaryl-5,11-dihydro-6H-dipyrido?3,2-B:2',3'-E!?1,4!diazepines and their use in the prevention or treatment of HIV infection
    Patent number: 5837704
    Abstract: Novel compounds for the treatment of HIV-1 infection. These are 2-heteroary-5,11-dihydro-6H-dipyrido?3,2-b:2',3'-e!?1,4!diazepines of the formula ##STR1## wherein Z is oxygen, sulfur, .dbd.NCN or .dbd.NOR.sup.
    Type: Grant
    Filed: August 1, 1996
    Date of Patent: November 17, 1998
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Karl Hargrave, John Proudfoot, Usha Patel, Suresh Kapadia, Terence Kelly, Daniel McNeil, Mario Cardozo