Abstract: Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing.

Abstract: An object-based data storage service receives a request to store a data object in association with a smart data storage tier. Based at least in part on characteristics of the data object, the object-based data storage service identifies and stores the data object in a first location corresponding to a first data storage tier. The object-based data storage service monitors access to the data object to identify a second set of characteristics of the data object. This second set of characteristics is used to determine that the data object is to be transitioned to a second data storage tier. The object-based data storage service, based at least in part on this determination, stores the data object in a second location corresponding to the second data storage tier.

Abstract: A surgical stapling system includes a surgical stapling apparatus and a staple cartridge surgical buttress assembly. The surgical stapling apparatus includes a handle assembly, an elongate tubular body extending distally from the handle assembly, and an end effector extending distally from the elongate tubular body. The end effector includes an anvil assembly and a staple cartridge assembly. The staple cartridge surgical buttress assembly includes a surgical buttress and a leash. The surgical buttress includes a body having an annular configuration and legs extending from the body. The body is positioned against a tissue facing surface of the staple cartridge assembly and the legs are positioned against a housing of the staple cartridge assembly. The leash is threaded through at least one of the legs and extends proximally from the surgical buttress towards the handle assembly.

Abstract: An anvil buttress loading system includes an anvil assembly, an anvil buttress loading tool, and an anvil buttress. The anvil buttress is releasably retained on the anvil buttress loading tool with a body of the anvil buttress is positioned on a base of the anvil buttress loading tool, a proximal tab of the anvil buttress positioned over a loading ramp of the anvil buttress loading tool, and a distal tab of the anvil buttress positioned within a flange of the anvil buttress loading tool. The anvil buttress is transferrable from the anvil buttress loading tool to the anvil assembly such that the anvil buttress is releasably secured to the anvil assembly with the body positioned on a tissue facing surface of the anvil assembly, the proximal tab engaged with a pin assembly of the anvil assembly, and the distal tab engaged with an anvil tip of the anvil assembly.

Abstract: A surgical stapling device includes a tool assembly including an anvil and a cartridge assembly that are movable in relation to each other between open and clamped positions. The cartridge assembly includes a staple cartridge that can be replaced after each firing of the stapling device to facilitate reuse of the stapling device. The anvil includes a lockout mechanism that prevents operation of the stapling device when the staple cartridge has been previously fired. The lockout mechanism is adapted to move from a locked position to an unlocked position when the staple cartridge is replaced and the tool assembly is moved from the open position to the clamped position.

Abstract: A method of monitoring an event that is expected to progress along a planned event route includes receiving an indication of a current location of the event as the event progresses along the planned event route. Camera feeds that correspond to the current location of the event as the event progresses along the planned event route are automatically identified, selected and displayed on a situation awareness wall. Camera feeds that correspond to an expected future position of the event as the event progresses along the planned event route are automatically selected and displayed. Camera feeds that correspond to a previous position of the event as the event progresses along the planned event route are automatically removed from the situation awareness wall.

Abstract: A safety housing based implant/medicament injecting system. System includes a needle assembly prefilled implant/medicament for injection and an injecting needle/cannula, a housing for accommodating the needle assembly under usual bias inside said housing, a plunger means having a plunger rod configured for stage wise forward motion including an initial injecting plunger forward motion with the needle assembly within the housing to first engage the needle assembly with the housing and subsequent continuing injecting plunger forward motion independent of the needle assembly for injecting of the implant/medicament, and post injecting return of the needle assembly secured inside said housing blocking any subsequent use thereof.

Abstract: A system includes a remote computer. The remote computer includes a processor and a memory. The memory stores instructions executable by the processor to receive location data of a plurality of satellite terminals, select, based on the received location data, for each of the plurality of satellite terminals, a respective satellite beam for providing satellite communications, and broadcast a message to the plurality of satellite terminals including data specifying respective selected satellite beams for each of the plurality of satellite terminals.

Abstract: Systems and methods implementing prioritization of network resources in an aeronautical satellite network system, which determines network utilization of a beam of the aeronautical satellite system by a plurality of aircraft using network capacity of the beam, where network demand in the beam indicated by the network utilization is greater than capacity of the beam, share network bandwidth of the beam to the plurality of aircraft based on a service priority factor, where the service priority factor may depend on altitude of the plurality of aircraft in the beam.

Abstract: The present invention provides immunostimulatory nucleic acids that have an affinity to a specific target protein. The present invention also provides templates and methods for making and using the immunostimulatory nucleic acids. Further, methods for linking the immunostimulatory nucleic acids to antigens and using the resulting complexes to enhance an immune response are provided.

Abstract: A meter case used with a utility meter is disclosed. The meter shell includes a plurality of snap fit joints assembled on the meter case arranged to engage a module cover to mount the module cover to the meter shell. The module cover further includes wire housing formed along an inner periphery of the module cover that houses a wire having a first end and a second end therein. A metal shield placed behind the meter shell is electrically coupled to a first connector. A terminal electrically connected to the metal shield is arranged to discharge current to ground. An electrical contact electrically coupled to the second end of the wire is arranged to engage the first connector to establish an electrical connection to the metal shield for the discharge to ground of electrostatic currents sensed by wire.

Abstract: Methods of making ?-homoamino acids as intermediate for synthesis of peptide monmer and dimer ?4?7-antagonists are disclosed. The disclosed methods include solid phase and solution phase methods.

Abstract: A system enabling hands-free operation of controls for accessing a transportation vehicle is provided. The system comprises code readers associated with respective entry barriers for admitting passengers to a transportation vehicle. The code readers read a machine-readable passenger code generated by a mobile electronic device and actuate mechanisms allowing entry through the barriers responsive confirmation of the code. A signal receiver in communication with a Passenger Service Unit for passenger seat onboard the vehicle receives instructions from the mobile electronic device and instruct the PSU to actuate passenger cabin controls for the passenger seat. An application on the mobile electronic device determines a time-stamped temperature of a passenger and generates the passenger code, which includes passenger identification, authorization to pass through the entry barriers and board the vehicle, and a determination if the temperature of the passenger indicates an acceptable passenger health status.

Abstract: An end effector for use with a surgical stapler includes a staple cartridge assembly movable relative to an anvil assembly. The staple cartridge assembly defines a plurality of retention slots and a cavity. The staple cartridge assembly includes a plurality of staples, a plurality of pushers, an actuation sled, a surgical buttress material, a suture, and an anchoring button. The actuation sled is configured for movement along a length of the staple cartridge assembly to sequentially engage the plurality of pushers to eject the plurality of staples through the respective plurality of retention slots. The anchoring button is configured to be received in the cavity of the staple cartridge assembly such that a portion of the suture is supported in the cavity to be severed by a knife blade of the actuation sled when the actuation sled is advanced distally.

Abstract: Examples described herein relate to a packet processing device that includes a programmable packet processing pipeline that is configured using a virtual switch. In some examples, the programmable packet processing pipeline is to receive configurations from multiple control planes via the virtual switch to configure packet processing actions. In some examples, the virtual switch is to provide inter-virtual execution environment communications. In some examples, the programmable packet processing pipeline is configured using a programming language.

Abstract: Application security analysis including systems and methods for analyzing applications for risk is provided. In an example method, the applications reside on a mobile device configurable to access an enterprise system. The example method includes evaluating each of a plurality of applications variously for privacy, data leakage, and malicious behavior. The example method also includes calculating a risk score for each of the plurality of applications based on the evaluating; and automatically remediating (e.g., quarantining) the applications, of the plurality of applications, for which the risk score meets or exceeds a risk score threshold. The method may evaluate all of the applications residing on a mobile device. The method may include grouping application behaviors, for each of the applications, that indicate an increased risk into groups comprising two or more of privacy risk, a data leakage risk, an account takeover risk, a device takeover risk, and a malware risk.

Abstract: The present invention relates a novel process for preparing a compound of Formula I, wherein, R1, R2, R3a, R3b, R3c, R4, R5, R6, R7 and Z are as defined in the description. The process comprises a novel and inventive step of converting a dione of Formula II into an isatoic anhydride of Formula V in a single step. wherein, R2 is F, Cl, Br or I; R1, R3a, R3b, R3c, R4, R5, R6, R7 and Z are as defined in the description.

Abstract: A safety housing based implant/medicament injecting system. System includes a needle assembly prefilled implant/medicament for injection and an injecting needle/cannula, a housing for accommodating the needle assembly under usual bias inside said housing, a plunger means having a plunger rod configured for stage wise forward motion including an initial injecting plunger forward motion with the needle assembly within the housing to first engage the needle assembly with the housing and subsequent continuing injecting plunger forward motion independent of the needle assembly for injecting of the implant/medicament, and post injecting return of the needle assembly secured inside said housing blocking any subsequent use thereof.

Abstract: A safety housing based implant/medicament injecting system. System includes a needle assembly prefilled implant/medicament for injection and an injecting needle/cannula, a housing for accommodating the needle assembly under usual bias inside said housing, a plunger means having a plunger rod configured for stage wise forward motion including an initial injecting plunger forward motion with the needle assembly within the housing to first engage the needle assembly with the housing and subsequent continuing injecting plunger forward motion independent of the needle assembly for injecting of the implant/medicament, and post injecting return of the needle assembly secured inside said housing blocking any subsequent use thereof.

Abstract: Provided is a system and method for heating an item in a microwave oven. The method includes capturing, with at least one electromagnetic field sensor, at least one electromagnetic field measurement of a microwave chamber, each electromagnetic field measurement of the at least one electromagnetic field measurement corresponding to a region in the microwave chamber, generating an electromagnetic field map of the microwave chamber based on the at least one electromagnetic field measurement, capturing, with at least one sensor, a plurality of thermal measurements of the item being heated in the microwave chamber, each thermal measurement of the plurality of thermal measurements corresponding to a region on the item, and controlling at least one of a position of the item and the electromagnetic field while the item is being heated in the microwave chamber based on the electromagnetic field map and the plurality of thermal measurements.