Abstract: The invention relates to a one pot process for preparing a ‘grit-free’ solid cleansing composition. The composition has pH resembling to skin pH which comprises hydrogenated triglyceride oil/s, humectant, sodium O-acyl isethionate as anionic surfactant, polyglyceryl ester, N-acyl glycine/s, water and, skin benefit agents and/or hair benefit agents. This is accomplished by a unique process using sodium O-acyl isethionates of particle size less than 250 ?m.

Abstract: Personal care compositions with N-capryloyl glutamine and glyceryl monoundecylenate as preservative are disclosed. The personal care composition with a combination of N-capryloyl L-glutamine (Formula I) and glyceryl monoundecylenate (Formula II) preserve the composition at broad range of pH between 3.0 to 7.0. The components of the preservative composition are manufactured by ‘Green’ processes that use bio-renewable starting raw materials.

Abstract: The invention relates to a process for preparing soap free, sulphate free and grit free solid cleansing composition. The composition has pH resembling to skin pH which comprises ‘non-soap’, ‘non-sulphate’ anionic surfactants and hydrogenated triglyceride oil/s, and optionally, skin benefit agents and/or hair benefit agents. This is accomplished by a unique short and cost-effective process without using any emulsifier or plasticizer. The process entails synthesizing sodium O-acyl isethionates by reacting fatty acid chloride with dry sodium methyl isethionate and sodium isethionate in a sequential manner followed by addition of hydrogenated triglyceride oil. The hot homogeneous paste of sodium O-acyl isethionates and vegetable oils is then flaked. The flakes are then kneaded in a sigma blender where other optional ingredients are mixed. The mass thus obtained is then further refined on a triple roll mill and plodded/extruded into billets or noodles.

Abstract: The present invention relates to novel processes for the preparation of enantiomerically enriched ?-amino acid derivatives such as ?-amino esters useful for the synthesis of enantiomerically enriched biologically active molecules such as sitagliptin. The key step involves the resolution of the racemate with mandelic acid.

Abstract: The present invention relates to novel processes for the preparation of enantiomerically enriched ?-amino acid derivatives such as ?-amino esters useful for the synthesis of enantiomerically enriched biologically active molecules such as sitagliptin. The key step involves the resolution of the racemate with mandelic acid.