Patents by Inventor Surinder K. Batra

Surinder K. Batra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for detection and treatment of cancer
    Patent number: 9403911
    Abstract: Novel antibodies for the detection and/or treatment of a cancer (e.g., a pancreatic cancer or an ovarian cancer) are provided. In certain embodiments the antibodies bind a region of the MUC4 protein that does not comprise the central tandem repeat (TR) domain of MUC4. Certain antibodies bind to the MUC4 peptide fragment MUC4-?-N-Ter and/or to the MUC4 peptide fragment MUC4-?-C-Ter. Chimeric constructs comprising such antibodies are also provided.
    Type: Grant
    Filed: June 6, 2012
    Date of Patent: August 2, 2016
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Surinder K. Batra, Maneesh Jain, Moorthy P. Ponnusamy
  • Compositions and methods for the treatment of cancer
    Patent number: 9233121
    Abstract: Compositions and methods for treating, detecting, and diagnosing cancer are disclosed.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: January 12, 2016
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Surinder K. Batra, Moorthy P. Ponnusamy
  • COMPOSITIONS AND METHODS FOR DETECTION AND TREATMENT OF CANCER
    Publication number: 20140199242
    Abstract: Novel antibodies for the detection and/or treatment of a cancer (e.g., a pancreatic cancer or an ovarian cancer) are provided. In certain embodiments the antibodies bind a region of the MUC4 protein that does not comprise the central tandem repeat (TR) domain of MUC4. Certain antibodies bind to the MUC4 peptide fragment MUC4-?-N-Ter and/or to the MUC4 peptide fragment MUC4-?-C-Ter. Chimeric constructs comprising such antibodies are also provided.
    Type: Application
    Filed: June 6, 2012
    Publication date: July 17, 2014
    Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Surinder K. Batra, Maneesh Jain, Moorthy P. Ponnusamy
  • Compositions and Methods for the Treatment of Cancer
    Publication number: 20140057962
    Abstract: Compositions and methods for treating, detecting, and diagnosing cancer are disclosed.
    Type: Application
    Filed: March 12, 2012
    Publication date: February 27, 2014
    Inventors: Surinder K. Batra, Moorthy P. Ponnusamy
  • Antibodies immunologically specific for PD2, a protein that is amplified and overexpressed in pancreatic cancer
    Patent number: 7166704
    Abstract: A human nucleic acid, PD2, its encoded protein and antibodies immunologically specific thereto are disclosed herein. The expression of the disclosed PD2 gene plays a key role in the regulation of differentiation and in the maintenance of the neoplastic state. The PD2 gene and its encoded protein represent valuable therapeutic targets in the differential diagnosis and therapy of pancreatic adenocarcinomas.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: January 23, 2007
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Surinder K. Batra, Michael A. Hollingsworth
  • Compositions and methods for inhibiting pancreatic cancer metastasis
    Patent number: 7105657
    Abstract: Methods are provided for the inhibition of metastasis of cancer cells expressing MUC4, metastatic pancreatic cancer cells.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: September 12, 2006
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Surinder K. Batra, Ajay P. Singh, Nicolas Moniaux
  • MUCIN 4 expression as a marker for pancreatic cancer
    Patent number: 7052859
    Abstract: Methods are provided for the diagnosis of pancreatic cancer.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: May 30, 2006
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Surinder K. Batra, Randall E Brand, Jöerg Ringel, Grit Faulmann, Matthias Löhr, Grish C. Varshney
  • Compositions and methods for inhibiting pancreatic cancer metastasis
    Publication number: 20040091869
    Abstract: Methods are provided for the inhibition of metastasis of cancer cells expressing MUC4, metastatic pancreatic cancer cells.
    Type: Application
    Filed: November 8, 2002
    Publication date: May 13, 2004
    Inventors: Surinder K. Batra, Ajay P. Singh, Nicolas Moniaux
  • Gene that is amplified and overexpressed in cancer and methods of use thereof
    Patent number: 6680196
    Abstract: A human nucleic acid, PD2, its encoded protein and antibodies immunologically specific thereto are disclosed herein. The expression of the disclosed PD2 gene plays a key role in the regulation of differentiation and in the maintenance of the neoplastic state. The PD2 gene and its encoded protein represent valuable therapeutic targets in the differential diagnosis and therapy of pancreatic adenocarcinomas.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: January 20, 2004
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Surinder K. Batra, Michael A. Hollingsworth
  • Specific mucin expression as a marker for pancreatic cancer
    Publication number: 20030134343
    Abstract: Methods are provided for the diagnosis of pancreatic cancer.
    Type: Application
    Filed: October 24, 2002
    Publication date: July 17, 2003
    Inventors: Surinder K. Batra, Randall E. Brand, Joerg Ringel, Grit Faulmann, Matthias Lohr, Grish C. Varshney
  • Specific mucin expression as a marker for pancreatic cancer
    Patent number: 6576423
    Abstract: Methods are provided for the diagnosis of pancreatic cancer.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: June 10, 2003
    Assignee: The Board of Regents of The University of Nebraska
    Inventors: Surinder K. Batra, Randall E. Brand, Jöerg Ringel, Grit Faulmann, Matthias Löhr, Grish C. Varshney
  • Specific mucin expression as a marker for pancreatic cancer
    Publication number: 20020150894
    Abstract: Methods are provided for the diagnosis of pancreatic cancer.
    Type: Application
    Filed: December 8, 2000
    Publication date: October 17, 2002
    Inventors: Surinder K. Batra, Randall E. Brand, Joerg Ringel, Grit Faulmann, Matthias Lohr, Grish C. Varshney