Patents by Inventor Suryanarayana Sankuratri

Suryanarayana Sankuratri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONJUGATE OF AN ANTIBODY AGAINST CCR5 AND AN ANTIFUSOGENIC PEPTIDE
    Publication number: 20110165182
    Abstract: The current invention is related to a conjugate comprising one or more antifusogenic peptides and an anti-CCR5 antibody (mAb CCR5) characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of said anti-CCR5 antibody and to the pharmaceutical use of said conjugate.
    Type: Application
    Filed: March 17, 2011
    Publication date: July 7, 2011
    Inventors: Michael Brandt, Stephan Fischer, Erhard Kopetzki, Suryanarayana Sankuratri, Ralf Schumacher
  • Conjugate of an antibody against CCR5 and an antifusogenic peptide
    Patent number: 7951920
    Abstract: The current invention is related to a conjugate comprising one or more antifusogenic peptides and an anti-CCR5 antibody (mAb CCR5) characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of the anti-CCR5 antibody and to the pharmaceutical use of the conjugate.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: May 31, 2011
    Assignee: Roche Palo Alto LLC
    Inventors: Michael Brandt, Stephan Fischer, Erhard Kopetzki, Suryanarayana Sankuratri, Ralf Schumacher
  • Method for screening human intestinal Npt2B modulatory agents
    Patent number: 7803562
    Abstract: A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: September 28, 2010
    Assignee: Roche Palo Alto LLC
    Inventors: Paul David Cannon, Suryanarayana Sankuratri
  • Human intestinal NPT2B
    Publication number: 20090170122
    Abstract: A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.
    Type: Application
    Filed: December 18, 2007
    Publication date: July 2, 2009
    Inventors: Paul David Cannon, Suryanarayana Sankuratri
  • Conjugate of an antibody against CCR5 and an antifusogenic peptide
    Publication number: 20090028881
    Abstract: The current invention is related to a conjugate comprising one or more antifusogenic peptides and an anti-CCR5 antibody (mAb CCR5) characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of said anti-CCR5 antibody and to the pharmaceutical use of said conjugate.
    Type: Application
    Filed: August 17, 2007
    Publication date: January 29, 2009
    Inventors: Michael Brandt, Stephan Fischer, Erhard Kopetzki, Suryanarayana Sankuratri, Ralf Schumacher
  • Conjugate of an antibody against CD4 and antifusogenic peptides
    Publication number: 20090022720
    Abstract: The current invention is related to a conjugate comprising two or more antifusogenic peptides and an anti-CD4 antibody (mAb CD4) characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of said anti-CD4 antibody and to the pharmaceutical use of said conjugate.
    Type: Application
    Filed: July 17, 2008
    Publication date: January 22, 2009
    Inventors: Stephan Fischer, Erhard Kopetzki, Stefan Ries, Suryanarayana Sankuratri
  • Synergistic compositions for treating HIV-1
    Publication number: 20080299132
    Abstract: Synergistic pharmaceutical compositions for treating or preventing HIV-1 infections comprising anti-CCR5 monoclonal antibodies and CCR5 antagonists, viral fusion inhibitors or viral attachment inhibitors are disclosed. The compositions exhibit significant greater activity than is anticipated from the activity of either component alone. Also provided are methods for treating or preventing HIV-1 using the same.
    Type: Application
    Filed: January 30, 2007
    Publication date: December 4, 2008
    Inventors: Changhua Ji, Suryanarayana Sankuratri
  • Human intestinal Npt2B
    Patent number: 7368530
    Abstract: A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.
    Type: Grant
    Filed: January 17, 2002
    Date of Patent: May 6, 2008
    Assignee: Roche Palo Alto LLC
    Inventors: Paul David Cannon, Suryanarayana Sankuratri
  • Peptide-immunoglobulin-conjugate
    Publication number: 20070148180
    Abstract: The current invention is related to peptide-immunoglobulin-conjugates in which at least two of the termini of the immunoglobulin polypeptide chains are conjugated to a peptide, whereby the peptides can be different, similar or identical. The conjugation is effected on the nucleic acid level.
    Type: Application
    Filed: October 19, 2006
    Publication date: June 28, 2007
    Inventors: Stephan Fischer, Erhard Kopetzki, Suryanarayana Sankuratri, Ralf Schumacher
  • Human intestinal Npt2B
    Publication number: 20020156266
    Abstract: A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.
    Type: Application
    Filed: January 17, 2002
    Publication date: October 24, 2002
    Inventors: Paul David Cannon, Suryanarayana Sankuratri
  • Human intestinal Npt2B
    Patent number: 6380374
    Abstract: A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.
    Type: Grant
    Filed: February 8, 2000
    Date of Patent: April 30, 2002
    Assignee: Roche Bioscience
    Inventors: Paul David Cannon, Suryanarayana Sankuratri