Patents by Inventor Susan A. Lyons

Susan A. Lyons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIAGNOSIS AND TREATMENT OF NEUROECTODERMAL TUMORS
    Publication number: 20120183544
    Abstract: The present invention provides fusion proteins for the detection and treatment of neuroectodermal tumors. Previous work demonstrated that chlorotoxin is specific for glial-derived or meningioma-derived tumor cells. The current invention has extended the use of chlorotoxin-cytotoxin fusion proteins to treat the whole class neuroectodermal tumors such as gliomas, meningiomas, ependymonas, medulloblastomas, neuroblastomas, gangliomas, pheochromocytomas, melanomas, PPNET's, small cell carcinoma of the lung, Ewing's sarcoma, and metastatic tumors in the brain. Also, diagnostic methods are provided for screening neoplastic neuroectodermal tumors.
    Type: Application
    Filed: January 19, 2012
    Publication date: July 19, 2012
    Applicant: THE UAB RESEARCH FOUNDATION
    Inventors: Harald W. Sontheimer, Susan A. Lyons
  • DIAGNOSIS AND TREATMENT OF NEUROECTODERMAL TUMORS
    Publication number: 20100215576
    Abstract: The present invention provides fusion proteins for the detection and treatment of neuroectodermal tumors. Previous work demonstrated that chlorotoxin is specific for glial-derived or meningioma-derived tumor cells. The current invention has extended the use of chlorotoxin-cytotoxin fusion proteins to treat the whole class neuroectodermal tumors such as gliomas, meningiomas, ependymonas, medulloblastomas, neuroblastomas, gangliomas, pheochromocytomas, melanomas, PPNET's, small cell carcinoma of the lung, Ewing's sarcoma, and metastatic tumors in the brain. Also, diagnostic methods are provided for screening neoplastic neuroectodermal tumors.
    Type: Application
    Filed: February 16, 2010
    Publication date: August 26, 2010
    Applicant: The UAB Research Foundation
    Inventors: Harald W. Sontheimer, Susan A. Lyons
  • Diagnosis and treatment of neuroectodermal tumors
    Patent number: 7678759
    Abstract: The present invention provides fusion proteins for the detection and treatment of neuroectodermal tumors. Previous work demonstrated that chlorotoxin is specific for glial-derived or meningioma-derived tumor cells. The current invention has extended the use of chlorotoxin-cytotoxin fusion proteins to treat the whole class neuroectodermal tumors such as gliomas, meningiomas, ependymonas, medulloblastomas, neuroblastomas, gangliomas, pheochromocytomas, melanomas, PPNET's, small cell carcinoma of the lung, Ewing's sarcoma, and metastatic tumors in the brain. Also, diagnostic methods are provided for screening neoplastic neuroectodermal tumors.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: March 16, 2010
    Assignee: TransMolecular, Inc.
    Inventors: Harald W. Sontheimer, Susan A. Lyons
  • Diagnosis and treatment of neuroectodermal tumors
    Publication number: 20040141981
    Abstract: The present invention provides fusion proteins for the detection and treatment of neuroectodermal tumors. Previous work demonstrated that chlorotoxin is specific for glial-derived or meningioma-derived tumor cells. The current invention has extended the use of chlorotoxin-cytotoxin fusion proteins to treat the whole class neuroectodermal tumors such as gliomas, meningiomas, ependymonas, medulloblastomas, neuroblastomas, gangliomas, pheochromocytomas, melanomas, PPNET's, small cell carcinoma of the lung, Ewing's sarcoma, and metastatic tumors in the brain. Also, diagnostic methods are provided for screening neoplastic neuroectodermal tumors.
    Type: Application
    Filed: October 17, 2003
    Publication date: July 22, 2004
    Applicant: UAB Research Foundation
    Inventors: Harald W. Sontheimer, Susan A. Lyons
  • Diagnosis and treatment of neuroectodermal tumors
    Patent number: 6667156
    Abstract: The present invention provides fusion proteins for the detection and treatment of neuroectodermal tumors. Previous work demonstrated that chlorotoxin is specific for glial-derived or meningioma-derived tumor cells. The current invention has extended the use of chlorotoxin-cytotoxin fusion proteins to treat the whole class neuroectodermal tumors such as gliomas, meningiomas, ependymonas, medulloblastomas, neuroblastomas, gangliomas, pheochromocytomas, melanomas, PPNET's, small cell carcinoma of the lung, Ewing's sarcoma, and metastatic tumors in the brain. Also, diagnostic methods are provided for screening neoplastic neuroectodermal tumors.
    Type: Grant
    Filed: April 21, 1999
    Date of Patent: December 23, 2003
    Assignee: UAB Research Foundation
    Inventors: Susan A. Lyons, Harald W. Sontheimer