Patents by Inventor Susan A. Steitz-Abadi

Susan A. Steitz-Abadi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microencapsulation and sustained release of biologically active polypeptides
    Patent number: 8129339
    Abstract: The invention relates to compositions and methods for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein a biologically active polypeptide, and a corticosteroid to modify the release profile and provide increased bioavailability.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: March 6, 2012
    Assignee: Alkermes Pharma Ireland Limited
    Inventors: Henry R. Costantino, Joyce M. Hotz, James R. Dasch, M. Gary I. Riley, Paul A. Burke, Susan A. Steitz-Abadi, Stephen E. Zale
  • Microencapsulation and sustained release of biologically active polypeptides
    Publication number: 20090281034
    Abstract: The invention relates to compositions and methods for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein a biologically active polypeptide, and a corticosteroid to modify the release profile and provide increased bioavailability.
    Type: Application
    Filed: November 6, 2008
    Publication date: November 12, 2009
    Inventors: Henry R. Costantino, Joyce M. Hotz, James R. Dasch, M. Gary I. Riley, Paul A. Burke, Susan A. Steitz-Abadi, Stephen E. Zale
  • Method of modifying the release profile of sustained release compositions
    Publication number: 20080057131
    Abstract: The present invention relates to a method for the sustained release in vivo of a biologically active labile agent comprising administering to a subject in need of treatment an effective amount of a sustained release composition comprising a biocompatible polymer having the biologically active labile agent incorporated therein, and a corticosteroid wherein the labile is released for a period of at least about two weeks. It is understood that the corticosteroid is present in an amount sufficient to modify the release profile of the biologically active labile agent from the sustained release composition. Pharmaceutical compositions suitable for use in the method of the invention are also disclosed.
    Type: Application
    Filed: July 17, 2007
    Publication date: March 6, 2008
    Applicant: Alkermes Controlled Therapeutics, Inc.
    Inventors: James Dasch, M. Gary Riley, Paul Burke, Susan Steitz-Abadi, Stephen Zale
  • Method of modifying the release profile of sustained release compositions
    Publication number: 20040121009
    Abstract: The present invention relates to a method for the sustained release in vivo of a biologically active labile agent comprising administering to a subject in need of treatment an effective amount of a sustained release composition comprising a biocompatible polymer having the biologically active labile agent incorporated therein, and a corticosteroid wherein the labile is released for a period of at least about two weeks. It is understood that the corticosteroid is present in an amount sufficient to modify the release profile of the biologically active labile agent from the sustained release composition. Pharmaceutical compositions suitable for use in the method of the invention are also disclosed.
    Type: Application
    Filed: October 8, 2003
    Publication date: June 24, 2004
    Applicant: Alkermes Controlled Therapeutics, Inc.
    Inventors: James R. Dasch, M. Gary I. Riley, Paul A. Burke, Susan A. Steitz-Abadi, Stephen E. Zale